Results 111 to 120 of about 3,665,294 (312)

Subtype‐specific enhancer RNAs define transcriptional regulators and prognosis in breast cancers

open access: yesMolecular Oncology, EarlyView.
This study employed machine learning methodologies to perform the subtype‐specific classification of RNA‐seq data sets, which are mapped on enhancers from TCGA‐derived breast cancer patients. Their integration with gene expression (referred to as ProxCReAM eRNAs) and chromatin accessibility profiles has the potential to identify lineage‐specific and ...
Aamena Y. Patel   +6 more
wiley   +1 more source

An IR-UWB photonic distribution system [PDF]

open access: yes, 2008
Experimental results are presented for a novel distribution system for an impulse radio ultra-wideband (UWB) radio signals employing a gain-switched laser.
Barry, Liam P.   +7 more
core   +1 more source

Stable Carbon Isotope Ratio (δ13C) Measurement of Graphite Using EA-IRMS System

open access: yesMedžiagotyra, 2015
δ13C values in non-irradiated natural graphite were measured. The measurements were carried out using an elemental analyzer combined with stable isotope ratio mass spectrometer (EA-IRMS). The samples were prepared with ground and non-ground graphite, the
Andrius Garbaras   +2 more
doaj   +1 more source

Network divergence analysis identifies adaptive gene modules and two orthogonal vulnerability axes in pancreatic cancer

open access: yesMolecular Oncology, EarlyView.
Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson   +9 more
wiley   +1 more source

Compressibility of biological systems: the viscoelastic Poisson’s ratio [PDF]

open access: yesAdvances in Physics: X
Soft tissues carry out their vital biological functions within a dynamic mechanical framework that can be extended or compressed. Externally or internally applied uni-axial or biaxial changes induce longitudinal strains that can be of either sign. The complex interrelationship between applied strain and induced strain is quantified by a time-space ...
Pajic-Lijakovic, Ivana   +2 more
openaire   +3 more sources

COMP–PMEPA1 axis promotes epithelial‐to‐mesenchymal transition in breast cancer cells

open access: yesMolecular Oncology, EarlyView.
This study reveals that cartilage oligomeric matrix protein (COMP) promotes epithelial‐to‐mesenchymal transition (EMT) in breast cancer. We identify PMEPA1 (protein TMEPAI) as a novel COMP‐binding partner that mediates EMT via binding to the TSP domains of COMP, establishing the COMP–PMEPA1 axis as a key EMT driver in breast cancer.
Konstantinos S. Papadakos   +6 more
wiley   +1 more source

Kernel-based nonlinear beamforming construction using orthogonal forward selection with Fisher ratio class separability measure

open access: yes, 2004
This letter shows that the wireless communication system capacity is greatly enhanced by employing nonlinear beamforming and the optimal Bayesian beamformer outperforms the standard linear beamformer significantly in terms of a reduced bit error rate, at
Wolfgang, A., Hanzo, L., Chen, S.
core  

Recovery Strategies for Combined Optical Storage Systems Based on System Short-Circuit Ratio (SCR) Thresholds

open access: yes
The penetration rate of variable energy sources in the current power grid is increasing, with the aim being to expand the use of these energy sources and to replace the traditional black start power supply.
Baohong Li   +3 more
core   +1 more source

Pre‐analytical optimization of cell‐free DNA and extracellular vesicle‐derived DNA for mutation detection in liquid biopsies

open access: yesMolecular Oncology, EarlyView.
Pre‐analytical handling critically determines liquid biopsy performance. This study defines practical best‐practice conditions for cell‐free DNA (cfDNA) and extracellular vesicle–derived DNA (evDNA), showing how processing time, storage conditions, tube type, and plasma input volume affect DNA integrity and mutation detection.
Jonas Dohmen   +11 more
wiley   +1 more source

A Residue Number System Based Parallel Communication Scheme using Orthogonal Signaling: Part I-System Outline

open access: yes, 2002
A novel signaling scheme is presented, where a set of orthogonal signals is transmitted in parallel. The signals are selected according to the so-called residue number system (RNS).
Yang, L-L., Hanzo, L.
core  

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