Results 91 to 100 of about 19,243,848 (252)

Campatibility of solitons within the frame work of Estevez-Mansfield-Clarkson equation

Partial Differential Equations in Applied Mathematics
This work suggests single-wave solutions for the Estevez-Mansfield-Clarkson (EMC) and linked sine-Gordon equations. The shape generation process in droplet form is studied using these model equations.
Nauman Ahmed, Sidra Ghazanfar, Zunaira, Muhammad Z. Baber, Ilyas Khan, Osama Oqilat, Wei Sin Kohh   +6 more
doaj   +1 more source

Importin 7 mediates the nuclear import of HIV‐1 integrase via a specific interacting interface

FEBS Open Bio, EarlyView.
HIV‐1 integrase enables viral DNA integration into the host genome. By binding to the core domain of the host protein Importin 7 via its C‐terminal domain, the integrase is transported across the nuclear membrane into the nucleus, where integration of the viral genome into host DNA takes place. This translocation is a critical step for subsequent viral
Juana Bana, Avigail Yariv, Tal Oppenheim, Hadar Amartely, Dana Reichmann, Oded Livnah   +5 more
wiley   +1 more source

Policy evaluation and design in the light of rational expectations [PDF]

This thesis examines certain key problems that the existence of forward rational expectations poses for policy analysis. The separate stages of estimating, testing and solving an econometric model are dealt with in turn. The main body of original work is
Snell, Andrew John
core  

A Novel Approach for Modeling Strain Hardening in Plasticity and Its Material Parameter Identification by Bayesian Optimization for Automotive Structural Steels Application

AppliedMath
Constitutive modeling in plasticity is a critical topic in solid mechanics. However, modeling nonlinear plasticity remains a challenge due to the theoretical complexity in representing realistic material behavior.
Teng Long, Leyu Wang, Cing-Dao Kan, James D. Lee   +3 more
doaj   +1 more source

In silico and in vitro exploration of a tyrosinase for biocatalytic production of catechols

FEBS Open Bio, EarlyView.
Tyrosinase from Ralstonia pseudosolanacearum is a promising biocatalyst for producing valuable catechols from monophenol substrates. This tyrosinase is uniquely suited to this due to its high monophenolase : diphenolase ratio. We combined in silico docking and in vivo kinetic characterisation of this tyrosinase with 11 industrially relevant monophenols,
James Britton, Fang Zhao, Reeta Davis, Meg Walsh, Kevin E O'Connor, David O'Connell, Tanja Narancic   +6 more
wiley   +1 more source

Exact Solitary Wave Solutions in Nonlinear Carbon Nanotube Composite Beams on Viscoelastic Foundations Under M-Truncated Derivative

Journal of Mathematics
In this study, the nonlinear partial differential equation that governs the free vibration of a carbon nanotube composite beam is analytically investigated using the truncated M-fractional derivative.
Nadia Javed, Nauman Ahmed, Muhammad Zafarullah Baber, Tukur Abdulkadir Sulaiman, Taha Radwan, Abeer S. Khalifa, Karim K. Ahmed   +6 more
doaj   +1 more source

From patient advocacy to patient‐driven research: Building active partnerships beginning at the bench to reach the bedside

FEBS Open Bio, EarlyView.
Research is strongest when conducted alongside patients, not just about them. Patient research organizations help integrate patient perspectives into research priorities, study design, and scientific meetings, leading to meaningful patient outcomes and development of relevant therapies.
Jenica H. Kakadia, Rachel Heilmann, Maximiliano Barrientos, Laura MacNeill, Ingrid Vallee, Sarah K. Schultz, Patrick O'Donoghue, Angelica A. Moresco, Victoria M. Siu, Ilka U. Heinemann   +9 more
wiley   +1 more source

The C‐terminal truncated splicing variant of NK1R negatively modulates substance P‐stimulated NK1R signaling

FEBS Open Bio, EarlyView.
The neurokinin 1 receptor exists as full‐length (NK1L) and C‐terminally truncated (NK1S) splice variants. We show that NK1S heterodimerizes with NK1L, impairing Gαq coupling and Ca2+ mobilization while enhancing β‐arrestin1 recruitment. NK1S suppresses substance P‐driven gene expression and cell migration, revealing NK1S as an endogenous biased ...
Lan Phuong Nguyen, Duc Trung Nguyen, Minyoung Cho, Jihun Kim, Soyeon In, Thai Uy Nguyen, Sunghoon Hurh, Beom Jin Park, Jong‐Ik Hwang   +8 more
wiley   +1 more source

Rational expectations business cycle models: a survey [PDF]

Development of rational expectations models of the business cycle has been the central issue in macroeconomics over the last 15 years. The postulate that expectations are rational imposes considerable discipline on business cycle analysis.
Robert G. King, Michael Dotsey
core  

Type I interferons modulate autophagy to shape gemcitabine response in pancreatic cancer cells

FEBS Open Bio, EarlyView.
Type I interferons differentially modulate autophagy and the response of pancreatic cancer cells to gemcitabine. IFNα2b stimulates autophagic flux and protects cells from gemcitabine‐induced cell death, contributing to chemoresistance. In contrast, IFNβ1a inhibits autophagosome formation and enhances gemcitabine‐induced cell death, resulting in ...
Lucy E. Bonilla, Martín M. Ledesma, Santiago A. Behr, Matías A. Pibuel, María L. Palanek, Daniel H. Grasso, Maria N. Garcia, Juan Garona, Silvina L. Lompardía, Elida Álvarez, Daniela L. Papademetrio   +10 more
wiley   +1 more source