Results 121 to 130 of about 596,163 (283)

Research in Further Education: Why we must make a fuss about it [PDF]

open access: yes, 2019
If FE wants a powerful voice in deciding its purpose and place in society and education, a policy to build research capacity in the sector is needed, say Dr Gary Husband and Sam Jones.Unabridged version available at: https://set.et-foundation.co.uk ...
Jones, Sam, Husband, Gary
core  

Integration of Reconfigurable p‐Bit and 1R Crossbar Array for Memristive Probabilistic Computing

open access: yesAdvanced Science, EarlyView.
A memristive probabilistic computing system is demonstrated by integrating stochastic p‐bits based on volatile memristors with a 1R crossbar array encoding interaction weights. The system performs weighted‐sum operations across the array and updates p‐bits iteratively.
Keunho Soh   +7 more
wiley   +1 more source

Intuition in software development revisited [PDF]

open access: yes, 2008
The role of intuition in software development was discussed in a most original fashion by Peter Naur in 1984. Yet there has been little subsequent interest in elaborating on Naur's ideas.
Boyatt, Russell   +2 more
core  

Engineering‐Modulated Molybdenum Enzymes Strategy for Tumor‐Specific Metabolic‐Immunotherapy

open access: yesAdvanced Science, EarlyView.
Biodegradable molybdenum sulfide nanoparticles were synthesized via a one‐pot strategy to increase molybdenum enzyme activity and thus effectively potentiate anti‐tumor immunity by integrating molybdenum‐based metalloimmunotherapy with hydrogen sulfide gas therapy.
Xiaoxiao Pan   +14 more
wiley   +1 more source

Computation and Structure‐Guided Arginine Scanning Engineers a Hyperactive AP Endonuclease for Multiplex Viral RNA Sensing

open access: yesAdvanced Science, EarlyView.
Computational and structure‐guided arginine scanning rewires the DNA‐binding interface of APE1 to create APE1‐Evo, a hyperactive yet specific AP endonuclease. Integrated into the NAPTUNE‐V2.0 cascade, APE1‐Evo enables amplification‐free, multiplex viral RNA sensing for dengue virus and influenza A/B, highlighting a general strategy for engineering ...
Junlan Wang   +20 more
wiley   +1 more source

Pensar y sentir, dos modos no antagónicos de la razón en Descartes

open access: yesRevista de Filosofia, 2008
The concept of reason that Descartes offers is not restricted alone to the intuition and deduction of clear, evident contents, which form understanding.
Leticia Rocha
doaj  

Review of Gastrointestinal Capsule Robots: Materials, Actuation, Diagnostics, and Therapeutics

open access: yesAdvanced Science, EarlyView.
This review examines gastrointestinal capsule robots through a systems engineering lens, covering shell materials, actuation and localization strategies, diagnostic modalities, therapeutic interventions, and commercialization status. By mapping the complete technological chain from fabrication to clinical deployment, this work identifies critical gaps ...
Zengsheng Li   +8 more
wiley   +1 more source

Philosophers, Autistics & Three Year Olds - Semantics & Intuition. [PDF]

open access: yes, 2013
Externalist theories in natural language semantics have become the orthodoxy since Kripke is widely thought to have refuted descriptive theories involving internal cognitive representation of meaning.
Slezak, Peter
core  

Unveiling Mechanisms of SEI Formation and Sodium Loss in Sodium Batteries via Interface Reactor Sampling

open access: yesAdvanced Science, EarlyView.
An “Interface Reactor” strategy boosts simulation stability by 2–3 orders of magnitude, enabling stable 100 ns molecular dynamics of electrode‐electrolyte interfaces. Distinct SEI formation mechanisms are revealed: mixed co‐formation in carbonates versus surface‐energy‐controlled NaF crystallization in ethers. Metadynamics simulations further elucidate
Zhoulin Liu   +6 more
wiley   +1 more source

UFL1‐Mediated UFMylation of ENO1 Restrains Aerobic Glycolysis and Colorectal Cancer Progression

open access: yesAdvanced Science, EarlyView.
UFMylation restrains aerobic glycolysis and colorectal cancer progression by modifying the glycolytic enzyme ENO1. Pharmacological enhancement of the UFL1–ENO1 interaction by the FDA‐approved antibiotic torezolid promotes ENO1 UFMylation, suppresses tumor metabolism, and sensitizes colorectal cancer to chemotherapy, revealing an actionable metabolic ...
Xiuqing Ma   +14 more
wiley   +1 more source

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