Results 51 to 60 of about 86,558 (263)
Molecular Oncology, EarlyView.In the present work, we have identified a transcriptional signature based on the differential expression of six genes (BCL2&MAST4, HSH2D&LAT2, METRN&PITPNM2) that would facilitate the early detection of T‐cell acute lymphoblastic leukemia (T‐ALL) patients prone to a poor treatment response and could be implemented at diagnosis, along with other risk ...
Antonio Lahera +11 more
wiley +1 more source
Weakly Coupled B-Type Kadomtsev-Petviashvili Equation: Lump and Rational Solutions
Advances in Mathematical Physics, 2020 Through the method of ZN-KP hierarchy, we propose a new (3+1)-dimensional weakly coupled B-KP equation. Based on the bilinear form, we obtain the lump and rational solutions to the dimensionally reduced cases by constructing a symmetric positive ...
Na Xiong, Wen-Tao Li, Biao Li
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Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer
Molecular Oncology, EarlyView.Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley +1 more source
Solutions Of The Rational Difference Equations
MANAS: Journal of Engineering, 2018 In this paper the solutions of the following difference equation is examined, (1)where the initial conditions are positive real numbers.
D. Şimşek, B. Oğul
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Solution and Attractivity for a Rational Recursive Sequence [PDF]
Discrete Dynamics in Nature and Society, 2011 This paper is concerned with the behavior of solution of the nonlinear difference equationxn+1=axn−1+bxnxn−1/(cxn+dxn−2),n= 0, 1, …, where the initial conditionsx−2,x−1,x0are arbitrary positive real numbers anda,b,c,dare positive constants. Also, we give specific form of the solution of four special cases of this equation.
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Loss of IGF‐1R impairs DNA‐PKcs recruitment to chromatin leading to defective end‐joining
Molecular Oncology, EarlyView.IGF‐1R promotes radioresistance by facilitating DNA‐PKcs recruitment to chromatin, enabling non‐homologous end‐joining (NHEJ) repair of double‐strand breaks. Inhibition or loss of IGF‐1R disrupts this recruitment to damage sites, driving compensatory reliance on microhomology‐mediated end‐joining (MMEJ) repair.
Matthew O. Ellis +3 more
wiley +1 more source
MITF maintains genome stability in nonmelanocyte lineages
Molecular Oncology, EarlyView.MITF is essential for melanocyte survival and acts as an oncogene in 10%–20% of melanomas. We show that MITF depletion causes genome instability in nonmelanocytic cells, leading to LATS2‐mediated P53 activation, cell cycle arrest, and apoptosis. This study highlights the role of MITF as a genome maintenance factor beyond the melanocyte lineage. Created
Drifa H. Gudmundsdottir +13 more
wiley +1 more source
Rationality and solutions to nonconvex bargaining problems: Rationalizability and Nash solutions [PDF]
Mathematical Social Sciences, 2013 zbMATH Open Web Interface contents unavailable due to conflicting licenses.
Yongsheng Xu 0003, Naoki Yoshihara
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Molecular Oncology, EarlyView.Single‐cell multi‐omics reveals epigenetic heterogeneity across therapy‐adaptive tumor states, including quiescent/dormant, drug‐tolerant persister, and EMT‐like phenotypes. By linking regulatory features with state‐associated biomarkers, these approaches inform biomarker‐guided therapeutic strategies for evolving tumors.
Hee Jung Kim +3 more
wiley +1 more source
Exact solutions of (3 + 1)-dimensional generalized KP equation arising in physics
Results in Physics, 2017 In this work, we have obtained some exact solutions to (3 + 1)-dimensional generalized KP Equation. The improved tanϕ(ξ)2-expansion method has been introduced to construct the exact solutions of nonlinear evolution equations.
Syed Tauseef Mohyud-Din +3 more
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