Results 71 to 80 of about 86,558 (263)

Somatostatin receptor 4 (SSTR4) is a tumor suppressor in cutaneous and head & neck squamous cell carcinomas

Molecular Oncology, EarlyView.
This study identifies somatostatin receptor 4 (Sstr4) as a critical tumor suppressor against skin and head/neck cancers (HNSCC, cSCC, and BCC). The loss of Sstr4 removes a check on cell growth, causing hyperactivation of the MAPK‐ERK signaling pathway (↑).
Ali Taqvi, Tuan Khang Huynh, Adway Kadam, Zahra Kardan, Yue Yan, Amina Jamal Laham, Sampath Kumar Loganathan   +6 more
wiley   +1 more source

Differential Relations for the Solutions to the NLS Equation and Their Different Representations

Communications in Advanced Mathematical Sciences, 2019
Solutions to the focusing nonlinear Schr\"odinger equation (NLS) of order $N$ depending on $2N-2$ real parameters in terms of wronskians and Fredholm determinants are given.
Pierre Gaillard
doaj   +1 more source

Castration‐resistant prostate cancer cells are addicted to the high activity of cyclin‐dependent kinase 2

Molecular Oncology, EarlyView.
We show that emergence of castration‐resistant prostate (CRPC) is associated with significant upregulation of cyclins that positively regulate cyclin‐dependent kinase 2 (CDK2) and concomitant downregulation of CDK4 cyclins. This renders CRPC cells dependent on the high activity of CDK2, and CDK2 inhibitors synergistically sensitize CRPC cells to both ...
Joyeeta Chatterjee, Alessia Marin, Shivani Yalala, Harri M. Itkonen   +3 more
wiley   +1 more source

Investigation of the new optical soliton solutions to the (2+1)-dimensional calogero-bogoyavlenskii schiff model

Scientific Reports
In this work, we use the ansatz transformation functions to investigate different analytical rational solutions by symbolic computation. For the (2+1)-dimensional Calogero-Bogoyavlenskii Schiff (CBS) model, we derive a variety of rational solutions, such
Sajawal Abbas Baloch, Muhammad Abbas, Muhammad Kashif Iqbal, Asnake Birhanu, M. R. Alharthi   +4 more
doaj   +1 more source

On a class of linear ordinary differential equations having ∑k=0∞xkδ(k)(t) and ∑k=0mxkδ(k)(t) as solutions

International Journal of Mathematics and Mathematical Sciences, 1996
We introduced some linear homogeneous ordinary differential equations which have both formal and finite distributional solutions at the same time, where the finite solution is a partial sum of the formal one.
Ahmed D. Alawneh, Ahmed Y. Farah
doaj   +1 more source

Partial FAK suppression promotes tumor growth, an effect reversed by macrophage p110δ PI3K inactivation

Molecular Oncology, EarlyView.
Partial inhibition of focal adhesion kinase (FAK) can paradoxically promote tumor growth, rather than simply producing a weaker antitumor effect than that observed with strong FAK suppression. In breast cancer and melanoma models, targeting p110δ PI3K, particularly in macrophages, counteracted these tumor‐promoting effects, highlighting the importance ...
Lydia Xenou, Niki Tzenaki, Anna Tsapara, Maria Tzardi, Evangelia A. Papakonstanti   +4 more
wiley   +1 more source

On the solutions of systems of rational difference equations

Mathematical and Computer Modelling, 2012
zbMATH Open Web Interface contents unavailable due to conflicting licenses.
Nouressadat Touafek, E. M. Elsayed
openaire   +1 more source

UiO‐66 metal–organic frameworks in biomedicine: From structural tunability to bioimaging, photodiagnostics, and photodynamic cancer therapy

FEBS Open Bio, EarlyView.
UiO‐66(Zr) metal–organic frameworks are chemically stable, biocompatible, and highly tunable nanomaterials. Their modular structure enables controlled drug delivery, multimodal bioimaging, and light‐activated photodynamic therapy, supporting integrated diagnostic and therapeutic (theranostic) applications in cancer and biomedical research.
Veronika Huntošová, Grigorii Rakhalskii, Miroslav Almáši   +2 more
wiley   +1 more source

M-shaped rational, homoclinic breather, kink-cross rational, multi-wave and interactional soliton solutions to the fifth-order Sawada-Kotera equation

Partial Differential Equations in Applied Mathematics
In this work, we develop multi-wave, homoclinic breathers, M-shaped rational, 1-kink interactions with M-shaped, periodic-cross rational and kink-cross rational solutions for the fifth-order Sawada-Kotera equation, which represents the motion of long ...
Sajawal Abbas Baloch, Muhammad Abbas, Farah Aini Abdullah, Mawahib Elamin, Mona Elmahi   +4 more
doaj   +1 more source

Complex optical solutions and modulation instability of hyperbolic Schrödinger dynamical equation

Results in Physics, 2019
Complex hyperbolic Schrödinger equation describes ultra-short pulse propagation in nonlinear media fiber optics. In this paper, new complex solutions for the complex hyperbolic Schrödinger equation are constructed using generalized elliptic equation ...
Wilson Osafo Apeanti, Aly R. Seadawy, Dianchen Lu   +2 more
doaj   +1 more source