Results 91 to 100 of about 615,488 (306)
Pure Science and Applied Science
Rambam Maimonides Medical Journal, 2011 (Excerpt) The name of my talk is Pure Science and Applied Science, and the idea I would like to sell to you today is that there is no such thing as “pure” or “applied” science.
Robert J. Aumann
doaj +1 more source
Structural stability and robustness to bounded rationality [PDF]
The introduction of a small amount of bounded rationality into a model sometimes has little effect, and sometimes has a dramatic impact on predicted behavior.
Anderlini, Luca, Canning, David
core
Rational Divisors in Rational Divisor Classes [PDF]
, 2004 We discuss the situation where a curve \(\mathcal{C}\), defined over a number field K, has a known K-rational divisor class of degree 1, and consider whether this class contains an actual K-rational divisor. When \(\mathcal{C}\) has points everywhere locally, the local to global principle of the Brauer group gives the existence of such a divisor.
Bruin, N, Flynn, E
openaire +3 more sources
Potential therapeutic targeting of BKCa channels in glioblastoma treatment
Molecular Oncology, EarlyView.This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak +4 more
wiley +1 more source
Weakest Collective Rationality and the Nash Bargaining Solution [PDF]
We propose a new axiom, Weakest Collective Rationality (WCR) which is weaker than both Weak Pareto Optimality (WPO) in Nash (1950)’s original characterization and Strong Individual Rationality (SIR) in Roth (1977)’s characterization of the Nash ...
Ching-jen Sun, Nejat Anbarci
core
Rationality of some tetragonal loci
, 2014 We prove that the moduli space of tetragonal curves of genus g>6 is rational when g is congruent to 1, 2, 5, 6, 9, 10 modulo 12 and not equal to 9, 45.Comment: to appear in Algebraic ...
Ma, Shouhei
core +1 more source
Exploiting metabolic adaptations to overcome dabrafenib treatment resistance in melanoma cells
Molecular Oncology, EarlyView.We show that dabrafenib‐resistant melanoma cells undergo mitochondrial remodeling, leading to elevated respiration and ROS production balanced by stronger antioxidant defenses. This altered redox state promotes survival despite mitochondrial damage but renders resistant cells highly vulnerable to ROS‐inducing compounds such as PEITC, highlighting redox
Silvia Eller +17 more
wiley +1 more source
Public attitudes towards social media field experiments
Scientific ReportsThe growing use of social media field experiments demands a rethink of current research ethics in computational social science and psychological research.
Vincent J. Straub +3 more
doaj +1 more source
Molecular Oncology, EarlyView.Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon +13 more
wiley +1 more source
Humanities & Social Sciences CommunicationsDoes the internet facilitate everyday public deliberation? Previous research on this question has largely focused on specific aspects, such as online news media diets or political discussions on social media.
Lisa Oswald
doaj +1 more source