Results 91 to 100 of about 182,763 (268)

More than news! Mapping the deliberative potential of a political online ecosystem with digital trace data

open access: yesHumanities & Social Sciences Communications
Does the internet facilitate everyday public deliberation? Previous research on this question has largely focused on specific aspects, such as online news media diets or political discussions on social media.
Lisa Oswald
doaj   +1 more source

The heterodimeric amino acid transporters (HAT) of the SLC7/SLC3 family: A structure−function relationships and relevance to human pathology

open access: yesFEBS Letters, EarlyView.
Heterodimeric amino acid transporters consist of SLC7 and SLC3 family proteins arranged in a conserved structural organization. They regulate nutrient transport across cell membranes, supporting essential cellular functions. These transporters also contribute to xenobiotic/drug uptake and distribution.
Mariafrancesca Scalise   +5 more
wiley   +1 more source

Extending the Bounded Rationality Model: The Distributed Cognition Approach [PDF]

open access: yes
The way Simon, and the major part of the scholars, presented and used bounded rationality directly refers to human computational capabilities (or “brute-force”).
Secchi Davide, Bardone Emanuele
core  

A context‐dependent modulatory role for eIF6 in acquired resistance to vemurafenib in melanoma

open access: yesFEBS Letters, EarlyView.
Acquired resistance to vemurafenib upregulates the translation factor eIF6 in melanoma cells. Silencing eIF6 in resistant cells reduces proliferation and partially restores drug sensitivity, whereas its overexpression increases sensitivity across melanoma lines regardless of BRAF status, via modulation of mTOR, S6K, and MAPK signaling.
George Kyriakopoulos   +9 more
wiley   +1 more source

From Bounded Rationality to Behavioral Economics [PDF]

open access: yes
The paper provides an brief overview of the “state of the art” in the theory of rational decision making since the 1950’s, and focuses specially on the evolutionary justification of rationality.
Massimo Egidi
core  

The normativity and reasonability of human rationality [PDF]

open access: yes, 2009
textIn my dissertation, I argue that rationality, for real humans, is best understood as a strategy for communication and interacting in a social environment.
Williams, Fred Madison
core  

Mapping Mental Representations With Free Associations: A Tutorial Using the R Package associatoR

open access: yesJournal of Cognition
People’s understanding of topics and concepts such as risk, sustainability, and intelligence can be important for psychological researchers and policymakers alike.
Samuel Aeschbach   +2 more
doaj   +1 more source

Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer

open access: yesMolecular Oncology, EarlyView.
Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley   +1 more source

Transcriptional profiling of circulating extracellular vesicles from prebiopsy prostate cancer patients

open access: yesMolecular Oncology, EarlyView.
RNA profiling of circulating extracellular vesicles (EVs) from blood samples of men undergoing prostate biopsy identifies transcripts associated with clinically significant prostate cancer. Integrative analysis with public tumor datasets links EV‐derived gene signatures to tumor stage and progression‐free survival, highlighting CASP3, XRCC2, and RIT1 ...
Stefan Werner   +14 more
wiley   +1 more source

Bounding Rationality by Discounting Time [PDF]

open access: yes
Consider a game where Alice generates an integer and Bob wins if he can factor that integer. Traditional game theory tells us that Bob will always win this game even though in practice Alice will win given our usual assumptions about the hardness of ...
Rahul Santhanam, Lance Fortnow
core  

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