Results 71 to 80 of about 47,038 (266)
Pure Science and Applied Science
Rambam Maimonides Medical Journal, 2011 (Excerpt) The name of my talk is Pure Science and Applied Science, and the idea I would like to sell to you today is that there is no such thing as “pure” or “applied” science.
Robert J. Aumann
doaj +1 more source
Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?
FEBS Letters, EarlyView.This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes +3 more
wiley +1 more source
FEBS Letters, EarlyView.We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee +3 more
wiley +1 more source
Public attitudes towards social media field experiments
Scientific ReportsThe growing use of social media field experiments demands a rethink of current research ethics in computational social science and psychological research.
Vincent J. Straub +3 more
doaj +1 more source
FEBS Letters, EarlyView.In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai +9 more
wiley +1 more source
Mediation Centrality in Adversarial Policy Networks
Complexity, 2019 Conflict resolution often involves mediators who understand the issues central to both sides of an argument. Mediators in complex networks represent key nodes that are connected to other key nodes in opposing subgraphs.
Stefan M. Herzog, Thomas T. Hills
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Are rational expectations really rational? [PDF]
Economics Letters, 1992 Abstract This article investigates whether ‘rational expectations’ are really rational, i.e. whether they maximize agents' utilities in some way. For that purpose we construct a model where each agent may have a whole array of expectations schemes, including the rational expectations one.
openaire +1 more source
Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
FEBS Letters, EarlyView.A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
wiley +1 more source
Humanities & Social Sciences CommunicationsDoes the internet facilitate everyday public deliberation? Previous research on this question has largely focused on specific aspects, such as online news media diets or political discussions on social media.
Lisa Oswald
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Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation
FEBS Letters, EarlyView.Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz +11 more
wiley +1 more source