Results 71 to 80 of about 615,488 (306)

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

open access: yesFEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee   +3 more
wiley   +1 more source

Adaptive mechanisms of social and asocial learning in immersive collective foraging

open access: yesNature Communications
Human cognition is distinguished by our ability to adapt to different environments and circumstances. Yet the mechanisms driving adaptive behavior have predominantly been studied in separate asocial and social contexts, with an integrated framework ...
Charley M. Wu   +5 more
doaj   +1 more source

Law for the Common Man: An Individual-Level Theory of Values, Expanded Rationality, and the Law [PDF]

open access: yes, 2011
This article makes an admittedly bold attempt at outlining an analytical framework for addressing this question. Instead of looking at the legal implications of bounded rationality -- an exercise highly worthy in its own right -- this article advances a ...
Licht, Amir N.
core   +1 more source

Epistemic Akrasia and Epistemic Reasons [PDF]

open access: yes, 2018
It seems that epistemically rational agents should avoid incoherent combinations of beliefs and should respond correctly to their epistemic reasons. However, some situations seem to indicate that such requirements cannot be simultaneously satisfied.
Daoust, Marc-Kevin
core   +1 more source

It’s time for rational rationing [PDF]

open access: yesBritish Journal of General Practice, 2013
> ‘Ask me my three main priorities for the NHS, and I tell you: efficiency, efficiency, efficiency.’ No government minister said this, at least not yet. Of course, the government wants quality too, but its war is on spending, and efficiency is its weapon. NHS spending power is set to remain stable at best for the foreseeable future.
openaire   +2 more sources

Structural biology of ferritin nanocages

open access: yesFEBS Letters, EarlyView.
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley   +1 more source

Reasons, Coherence, and Group Rationality [PDF]

open access: yes, 2019
Philosophy and Phenomenological Research ...
Arrow K.   +19 more
core   +2 more sources

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

open access: yesFEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai   +9 more
wiley   +1 more source

Practical Reasoning and Rationality [PDF]

open access: yes, 2013
Proceedings of the DRUMS II Workshop 9 - 11 February 1996, Windsor, UK (Funded by Esprit III BRA ...
Bell, John, Huang, Zhisheng
core  

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

open access: yesFEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa   +5 more
wiley   +1 more source

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