Results 61 to 70 of about 182,763 (268)
Pubertal testosterone correlates with adolescent impatience and dorsal striatal activity
Developmental Cognitive Neuroscience, 2020 Recent self-report and behavioral studies have demonstrated that pubertal testosterone is related to an increase in risky and impulsive behavior. Yet, the mechanisms underlying such a relationship are poorly understood.
Corinna Laube +2 more
doaj +1 more source
FEBS Letters, EarlyView.The process of internalization of the Shiga toxin A subunit via formation of a complex with the Shiga toxin B subunit, which specifically binds to the Gb3 receptor. The peptide is designed to act as a carrier of drugs into cancer cells. Here, we explored the potential of peptides derived from the catalytic A subunit of Shiga toxin (STxA) to be drug ...
Giulia Opassi +6 more
wiley +1 more source
openChe cosa è la razionalità? Sulla base di questa complessa domanda l'elaborato scritto si propone di fornire gli strumenti teorico concettuali grazie ai quali orientarsi attraverso il labirinto di un dibattito complesso e vasto.
PAGANI, RICCARDO
core
Investigating transcription factor dynamics in health and disease using FRAP
FEBS Letters, EarlyView.FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj +3 more
wiley +1 more source
Structural stability and robustness to bounded rationality [PDF]
The introduction of a small amount of bounded rationality into a model sometimes has little effect, and sometimes has a dramatic impact on predicted behavior.
Canning, David, Anderlini, Luca
core
Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions
FEBS Letters, EarlyView.The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang +4 more
wiley +1 more source
Testing Bounded Rationality Against Full Rationality in Job Changing Behavior [PDF]
In this paper I question the hypothesis of full rationality in the context of job changing behaviour, via simple econometric explorations on microdata drawn from WHIP (Worker Histories Italian Panel).
Bruno Contini
core
Deliberately ignoring inequality to avoid rejecting unfair offers
Communications PsychologyWhy do people punish experienced unfairness if it induces costs for both the punisher and punished person(s) without any direct material benefits for the punisher?
Konstantin Offer +3 more
doaj +1 more source
Structure‐forward targeting of claudins with synthetic binders
FEBS Letters, EarlyView.Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley +1 more source
Social Influence in Adolescent Decision-Making: A Formal Framework
Frontiers in Psychology, 2019 Adolescence is a period of life during which peers play a pivotal role in decision-making. The narrative of social influence during adolescence often revolves around risky and maladaptive decisions, like driving under the influence, and using illegal ...
Simon Ciranka +4 more
doaj +1 more source