Results 101 to 110 of about 1,523,647 (396)
The observation of the actual behavior by economic decision makers in the lab and in the field justifies that bounded rationality has been a generally accepted assumption in many socio-economic models.
Coralio Ballester, Penelope Hernandez
core
Inhibition of CDK9 enhances AML cell death induced by combined venetoclax and azacitidine
Molecular Oncology, EarlyView.The CDK9 inhibitor AZD4573 downregulates c‐MYC and MCL‐1 to induce death of cytarabine (AraC)‐resistant AML cells. This enhances VEN + AZA‐induced cell death significantly more than any combination of two of the three drugs in AraC‐resistant AML cells.
Shuangshuang Wu +18 more
wiley +1 more source
Chimpanzees adapt their exploration to key properties of the environment
Nature CommunicationsExploration is an important strategy for reducing the uncertainty that pervades daily life. Yet the evolutionary roots of adaptive exploration are poorly understood.
Lou M. Haux +3 more
doaj +1 more source
Pure Science and Applied Science
Rambam Maimonides Medical Journal, 2011 (Excerpt) The name of my talk is Pure Science and Applied Science, and the idea I would like to sell to you today is that there is no such thing as “pure” or “applied” science.
Robert J. Aumann
doaj +1 more source
Molecular Oncology, EarlyView.This study characterizes the responses of primary acute myeloid leukemia (AML) patient samples to the MCL‐1 inhibitor MIK665. The results revealed that monocytic differentiation is associated with MIK665 sensitivity. Conversely, elevated ABCB1 expression is a potential biomarker of resistance to the treatment, which can be overcome by the combination ...
Joseph Saad +17 more
wiley +1 more source
Rational Divisors in Rational Divisor Classes [PDF]
, 2004 We discuss the situation where a curve \(\mathcal{C}\), defined over a number field K, has a known K-rational divisor class of degree 1, and consider whether this class contains an actual K-rational divisor. When \(\mathcal{C}\) has points everywhere locally, the local to global principle of the Brauer group gives the existence of such a divisor.
Bruin, N, Flynn, E
openaire +3 more sources
Molecular Oncology, EarlyView.Detection of extrachromosomal circular DNA (eccDNA) in plasma samples from EGFR‐mutated non‐small cell lung cancer patients. Plasma was collected before and during treatment with the EGFR‐tyrosine kinase inhibitor osimertinib. Plasma eccDNA was detected in all cancer samples, and the presence of the EGFR gene on eccDNA serves as a potential biomarker ...
Simone Stensgaard +5 more
wiley +1 more source
Rationality, perception, and the all-seeing eye
Psychonomic Bulletin & Review, 2016 Seeing—perception and vision—is implicitly the fundamental building block of the literature on rationality and cognition. Herbert Simon and Daniel Kahneman’s arguments against the omniscience of economic agents—and the concept of bounded rationality ...
Teppo Felin, J. Koenderink, J. Krueger
semanticscholar +1 more source
Intein‐based modular chimeric antigen receptor platform for specific CD19/CD20 co‐targeting
Molecular Oncology, EarlyView.CARtein is a modular CAR platform that uses split inteins to splice antigen‐recognition modules onto a universal signaling backbone, enabling precise, scarless assembly without re‐engineering signaling domains. Deployed here against CD19 and CD20 in B‐cell malignancies, the design supports flexible multi‐antigen targeting to boost T‐cell activation and
Pablo Gonzalez‐Garcia +9 more
wiley +1 more source
Public attitudes towards social media field experiments
Scientific ReportsThe growing use of social media field experiments demands a rethink of current research ethics in computational social science and psychological research.
Vincent J. Straub +3 more
doaj +1 more source