Results 91 to 100 of about 1,773,167 (249)

RATIO AND DIVISION [PDF]

open access: yesSchool Science and Mathematics, 1908
n ...
openaire   +2 more sources

Prévention de la défaillance des entreprises

open access: yesRevue Marocaine de Recherche en Management et Marketing, 2016
La défaillance représente un évènement spécifique dans la vie de l’entreprise. Il s’agit d’un épisode où celle-ci souffre de dysfonctionnements graves qui compromettent sa continuité et sa survie.
Mohammed HASSAINATE
doaj  

Network divergence analysis identifies adaptive gene modules and two orthogonal vulnerability axes in pancreatic cancer

open access: yesMolecular Oncology, EarlyView.
Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson   +9 more
wiley   +1 more source

COMP–PMEPA1 axis promotes epithelial‐to‐mesenchymal transition in breast cancer cells

open access: yesMolecular Oncology, EarlyView.
This study reveals that cartilage oligomeric matrix protein (COMP) promotes epithelial‐to‐mesenchymal transition (EMT) in breast cancer. We identify PMEPA1 (protein TMEPAI) as a novel COMP‐binding partner that mediates EMT via binding to the TSP domains of COMP, establishing the COMP–PMEPA1 axis as a key EMT driver in breast cancer.
Konstantinos S. Papadakos   +6 more
wiley   +1 more source

Pre‐analytical optimization of cell‐free DNA and extracellular vesicle‐derived DNA for mutation detection in liquid biopsies

open access: yesMolecular Oncology, EarlyView.
Pre‐analytical handling critically determines liquid biopsy performance. This study defines practical best‐practice conditions for cell‐free DNA (cfDNA) and extracellular vesicle–derived DNA (evDNA), showing how processing time, storage conditions, tube type, and plasma input volume affect DNA integrity and mutation detection.
Jonas Dohmen   +11 more
wiley   +1 more source

EDNRB‐dependent endothelin signaling reduces proliferation and promotes proneural‐to‐mesenchymal transition in gliomas

open access: yesMolecular Oncology, EarlyView.
Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau   +36 more
wiley   +1 more source

Treat, follow-up, or discharge? An aid in sonographic decisions for the borderline centered neonatal/infantile hips

open access: yesJournal of Ultrasonography
To investigate whether linear measurements or ratios on the Graf’s “standard plane” ultrasound images of the neonatal/infantile hip, can support the clinically important differentiation between type I and type II hips.
Chlapoutakis Konstantinos   +6 more
doaj   +1 more source

Una introducción a la investigación webmétrica de empresas [PDF]

open access: yesGestión Joven, 2009
La Web ha experimentado un enorme desarrollo en los últimos 20 años. La Webmetría se presenta como una nueva disciplina que pretende estudiar desde un punto de vista cuantitativo este nuevo canal de comunicación mediante la adaptación y aplicación de ...
Romero Frías, Esteban
doaj  

Engineered extracellular vesicles enriched with the miR‐214/199a cluster enhance the efficacy of chemotherapy in ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang   +12 more
wiley   +1 more source

Comparison of the Isokinetic Torque Ratios and the Ratios of the Tensiomyographic Parameters of the Knee Muscles in Healthy Young Adults

open access: yesApplied Sciences
Isokinetic dynamometry is considered the gold standard for assessing muscle strength ratios, whereas tensiomyography (TMG) has emerged as a promising tool for rapid assessment of involuntary muscle contractility.
Daša Weber, Ajda Hrastnik, Alan Kacin
doaj   +1 more source

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