Results 11 to 20 of about 14,911 (165)

Nest-building behaviour in male rats from three inbred strains: BN/HsdCpb, BDIX/Or1Ico and LEW/Mol

Animal Welfare, 2005
AbstractThree inbred strains of male laboratory rat (BN/HsdCpb, BDIX/Or1Ico and LEW/Mol) were provided with nest boxes and nest materials, and were observed for nest-building activity. After 7 days, each cage and nest box was examined. Each nest was weighed and scored for complexity, and returned to the cage.
IM Jegstrup, R Vestergaard, W Vach, M Ritskes-Hoitinga   +3 more
openaire   +2 more sources

Genetic control of differential acetylation in diabetic rats.

PLoS ONE, 2014
Post-translational protein modifications such as acetylation have significant regulatory roles in metabolic processes, but their relationship to both variation in gene expression and DNA sequence is unclear. We address this question in the Goto-Kakizaki (
Pamela J Kaisaki, Georg W Otto, Joanna F McGouran, Amine Toubal, Karène Argoud, Helen Waller-Evans, Clare Finlay, Sophie Caldérari, Marie-Thérèse Bihoreau, Benedikt M Kessler, Dominique Gauguier, Richard Mott   +11 more
doaj   +1 more source

Genetic background specific hypoxia resistance in rat is correlated with balanced activation of a cross-chromosomal genetic network centering on physiological homeostasis

Frontiers in Genetics, 2012
Genetic background of an individual can drastically influence an organism’s response upon environmental stress and pathological stimulus. Previous studies in inbred rats showed that compared to Brown Norway (BN), Dahl salt-sensitive (SS) rat exerts ...
Lei eMao
doaj   +1 more source

Nociception and conditioned fear in rats: strains matter.

PLoS ONE, 2013
When using rats in pain research, strain-related differences in outcomes of tests for pain and nociception are acknowledged. However, very little is known about the specific characteristics of these strain differences. In this study four phylogenetically
Manon W H Schaap, Hugo van Oostrom, Arie Doornenbal, José van 't Klooster, Annemarie M Baars, Saskia S Arndt, Ludo J Hellebrekers   +6 more
doaj   +1 more source

Spontaneous Recurrent Absence Seizure-like Events in Wild-Caught Rats

Journal of Neuroscience, 2019
Absence epilepsy is a heritable human neurological disorder characterized by brief nonconvulsive seizures with behavioral arrest, moderate-to-severe loss of consciousness (absence), and distinct spike-wave discharges (SWDs) in the EEG and ...
Jeremy A. Taylor, Jon D. Reuter, Rebecca A. Kubiak, Toni T. Mufford, Carmen J. Booth, F. Dudek, Daniel S. Barth   +6 more
semanticscholar   +1 more source

Sex-specific nicotine sensitization and imprinting of self-administration in rats inform GWAS findings on human addiction phenotypes

Neuropsychopharmacology, 2021
Repeated nicotine exposure leads to sensitization (SST) and enhances self-administration (SA) in rodents. However, the molecular basis of nicotine SST and SA and their biological relevance to the mounting genome-wide association study (GWAS) loci of ...
A. Kozlova, R. Butler, Siwei Zhang, T. Ujas, Hanwen Zhang, S. Steidl, A. Sanders, Z. Pang, P. Vezina, J. Duan   +9 more
semanticscholar   +1 more source

Cerebellar output controls generalized spike-and-wave discharge occurence [PDF]

, 2015
© 2015 The Authors Annals of Neurology published by Wiley Periodicals, Inc. on behalf of American Neurological Association. This is an open access article under the terms of the Creative Commons Attribution-NonCommercial-NoDerivs License (CC BY-NC-ND 4.0)
Alva, Parimala, Davey, N., De Zeeuw, Chris I., Eelkman Rooda, Oscar, Hoebeek, Freek E., Karapatis, Athanasios, Kros, Lieke, Negrello, Mario, Serdijn, Wouter, Spanke, Jochen, Steuber, Volker, Strydis, Christos, Tolner, Else, van den Maagdenberg, Arn, van Dongen, Marijn, Winkelman, Beerend   +15 more
core   +7 more sources

Ribonuclease (RNase) Prolongs Survival of Grafts in Experimental Heart Transplantation

Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, 2016
BackgroundCell damage, tissue and vascular injury are associated with the exposure and release of intracellular components such as RNA, which promote inflammatory reactions and thrombosis. Based on the counteracting anti‐inflammatory and cardioprotective
Eike Kleinert, Martin C. Langenmayer, Bruno Reichart, Jana Kindermann, Barbara Griemert, Andreas Blutke, Kerstin Troidl, Tanja Mayr, Tobias Grantzow, Fatih Noyan, Jan‐Michael Abicht, Silvia Fischer, Klaus T. Preissner, Ruediger Wanke, Elisabeth Deindl, Sonja Guethoff   +15 more
doaj   +1 more source

Rat Strain Ontology: structured controlled vocabulary designed to facilitate access to strain data at RGD [PDF]

, 2013
BACKGROUND: The Rat Genome Database (RGD) ( http://rgd.mcw.edu/) is the premier site for comprehensive data on the different strains of the laboratory rat (Rattus norvegicus).
Diane H Munzenmaier, Elizabeth A Worthey, Howard J Jacob, Mary Shimoyama, Melinda R Dwinell, Rajni Nigam   +5 more
core   +2 more sources

Von Willebrand Factor Gene Variants Associate with Herpes simplex Encephalitis.

PLoS ONE, 2016
Herpes simplex encephalitis (HSE) is a rare complication of Herpes simplex virus type-1 infection. It results in severe parenchymal damage in the brain.
Nada Abdelmagid, Biborka Bereczky-Veress, Santosh Atanur, Alena Musilová, Václav Zídek, Laura Saba, Andreas Warnecke, Mohsen Khademi, Marie Studahl, Elisabeth Aurelius, Anders Hjalmarsson, Ana Garcia-Diaz, Cécile V Denis, Tomas Bergström, Birgit Sköldenberg, Ingrid Kockum, Timothy Aitman, Norbert Hübner, Tomas Olsson, Michal Pravenec, Margarita Diez   +20 more
doaj   +1 more source