Results 21 to 30 of about 13,927 (161)

Hydroxylation of CMP-NeuAc controls the expression of N-glycolylneuraminic acid in GM3 ganglioside of the small intestine of inbred rats.

Journal of Biological Chemistry, 1989
An enzymatic activity responsible for the hydroxylation of CMP-NeuAc into CMP-N-glycolylneuraminic acid (CMP-NeuGc) was found in the cytosolic fraction after cellular fractionation of the mucosa of rat small intestine.
J. Bouhours, D. Bouhours
semanticscholar   +1 more source

Glucocorticoid negative feedback on the HPA axis in five inbred rat strains

, 1998
The aim of the present work was to study the influence of altering glucocorticoid negative feedback on both basal activity of the hypothalamic-pituitary-adrenal (HPA) axis and its response to acute stress (tail shock) in five inbred rat strains known to
E. Ronald De Kloet, Antonio Armario, Francisca Gómez   +2 more
core   +1 more source

Characteristics of the aortic elastic network and related phenotypes in seven inbred rat strains.

, 2005
Extracellular matrix (ECM) molecules such as elastin and collagen provide mechanical support to the vessel wall and are essential for vascular function.
Jacob, MP, Gauguier, Dominique, Osborne-Pellegrin, M, Behmoaras, J   +3 more
core   +1 more source

Tissue-specific expression of GM3(NeuGc) and GD3(NeuGc) in epithelial cells of the small intestine of strains of inbred rats. Absence of NeuGc in intestine and presence in kidney gangliosides of brown Norway and spontaneously hypertensive rats.

Journal of Biological Chemistry, 1988
The ganglioside composition of the epithelial cells of the small intestine was investigated in 15 strains of inbred rats. Most of these strains had GM3 as the only detectable ganglioside.
D. Bouhours, J. Bouhours
semanticscholar   +1 more source

Genetic influences on survival time after severe hemorrhage in inbred rat strains

, 2011
To find a genetic basis for differential ability to survive severe hemorrhage, we previously showed eightfold differences in survival times among inbred rat strains. We assumed that rat strains had similar normalized blood volumes (NBV; ml/100 g body wt).
Harold G. Klemcke, Mariam L. Calderon, Rajiv Rose, James Aden, Thomas Oh, Kathy L. Ryan, Bina Joe   +6 more
core   +1 more source

Genetic variation influences immune responses in sensitive rats following exposure to TiO2 nanoparticles

, 2014
This study examines the immunological responses in rats following inhalation to titanium dioxide nanoparticles (TiO2 NPs), in naïve rats and in rats with induced allergic airway disease.
Gustafsson, A, Bucht, A, Lorentzen, JC, Jonasson, Sofia,, Gustafsson, Åsa,, Bucht, Anders,, Sandström, Thomas,, Lorentzen, Johnny,, Jonasson, S, Sandstrom, T   +9 more
core   +1 more source

A novel rodent model of pregnancy complications associated with genetically determined angiotensin-converting enzyme (ACE) activity

, 2018
Brown Norway (BN) and Lewis (LW) inbred rat strains harbor different angiotensin-converting enzyme ( Ace) polymorphisms that result in higher ACE activity in BN than LW rats.
Shannon L. Bragg, LeeAnna D. Sands, Arlin B. Blood, Daliao Xiao, Lubo Zhang, Eugenia Mata-Greenwood   +5 more
core   +1 more source

Angiotensin I-Converting Enzyme Genotype Influences Arterial Response to Injury in Normotensive Rats

, 1998
—Two normotensive strains of rat, the Lou and Brown Norway (BN) strains, have contrasting levels of plasma angiotensin-converting enzyme (ACE). To investigate the degree of genetic determination of ACE expression, a polymorphic marker of the ACE gene was
Jean-Paul Vilaine, Florent Soubrier, Eric Villard, Monique Philippe, Bruno Giraudeau, Philip Janiak, Jean-Baptiste Michel, Mireille Challah, Antoine Ribadeau-Dumas   +8 more
core   +1 more source

An Animal Model of Cutaneous Cyst Development Enables the Identification of Three Quantitative Trait Loci, Including the Homologue of a Human Locus (TRICY1) [PDF]

, 2019
Using inbred BN and LE/Stm rats susceptible and resistant, respectively, to chemically induced cutaneous cyst development we were able to further unveil the genetic architecture of inherited multiple cyst formation.
Cosgarea, I, van den Berg, L, Kutritz, A, Kindler-Röhrborn, A, Kindler-Röhrborn, Andrea, Koelsch, B, Griewank, K G, Schadendorf, D, Koelsch, B., Cosgarea, Ioana, van den Berg, L., Kutritz, Anja, Griewank, Klaus G., Fischer, Christine, Schadendorf, Dirk, Fischer, C   +15 more
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Proliferative autoimmune glomerulonephritis in rats: A model for autoimmune glomerulonephritis in humans

, 1993
Proliferative autoimmune glomerulonephritis: A model for autoimmune glomerulonephritis in humans. Some forms of glomerulonephritis (GN) in humans appear consequent to autoimmunity.
Sturgill, Benjamin C., Bolton, W. Kline, May, Walter J.   +2 more
core   +1 more source