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Performance of cryptogenic new onset refractory status epilepticus score in a Brazilian cohort after testing for antineuronal antibodies with tissue‐based and cell‐based assays
Epilepsia, Volume 66, Issue 7, Page 2285-2294, July 2025.Abstract Objective
This study was undertaken to describe a case series of Brazilian new onset refractory status epilepticus (NORSE) patients and evaluate the sensitivity and specificity of a clinical score to predict cryptogenic etiology (c‐NORSE score) after autoimmune encephalitis (AE) testing.João Henrique Fregadolli Ferreira, Anna Maria Gomes, Ana Carolina Zetehaku, Taissa Ferrari Marinho, Fabio Fieni Toso, Caio César Diniz Disserol, Mariana Braatz Krueger, Mara Lúcia Schmitz Ferreira Santos, Aline Freire Borges Juliano, Tércio Luz Barbosa, Letícia Januzi de Almeida Rocha, Fernando Tenório Gameleira, Renata Barbosa Paolilo, Vanessa Daccach, João Pedro Izidoro Gomes, Katia Lin, Adaucto Wanderley da Nóbrega Jr., Emily Lima Marmentini, Eduardo Ferracioli Fusão, Anderson de Cuffa, Georgia Lelis Aranha Tavares, Ronaldo Maciel Dias, Sabrina Stephanie Lana Diniz, Fábio Siquineli, Pedro Braga‐Neto, Paulo Ribeiro Nobrega, Lorena Pitombeira Sanders, Fernanda Martins Maia Carvalho, Renata Brasileiro Reis Pereira, Eduardo Sousa de Melo, Adélia Maria de Miranda Henriques‐Souza, Clecio de Oliveira Godeiro Jr., Omar Gurrola Arambula, Filipe Nolasco de Souza e Silva, Karla Oliveira Couto, Dayane Danieli, Katia Werneck Seitz, Alessandra Dellavance, Verena Endmayr, Romana Höftberger, Luis Eduardo Coelho Andrade, Luis Otavio Caboclo, Livia Almeida Dutra +42 morewiley +1 more sourceTopological Analysis of Metabolic Networks Integrating Co-Segregating Transcriptomes and Metabolomes in Type 2 Diabetic Rat Congenic Series [PDF]
, 2016 Background: The genetic regulation of metabolic phenotypes (i.e., metabotypes) in type 2 diabetes mellitus is caused by complex organ-specific cellular mechanisms contributing to impaired insulin secretion and insulin resistance.Argoud, K, Ayala, R, Calderari, S, Cazier, JB, Collins, S, Domange, C, Dumas, ME, Gauguier, D, Gu, Q, Holmes, E, Hue, C, Lindon, JC, Mitchell, S, Navratil, V, Nicholson, JK, Otto, GW, Rodriguez Martinez, A, Suárez-Zamorano, N, Wallis, R, Wang, Y, Wilder, S +20 morecore +6 more sourcesPositional identification of variants of Adamts16 linked to inherited hypertension [PDF]
, 2017 A previously reported blood pressure (BP) quantitative trait locus on rat Chromosome 1 was isolated in a short congenic segment spanning 804.6 kb. The 804.6 kb region contained only two genes, LOC306664 and LOC306665.Achinike, Ovokeraye H., Apte, Suneel S., Bouchard, Claude, Chakravarti, Aravinda, Coe, David, Cooper, Richard S., Ehret, Georg B., Farms, Phyllis, Frank, Bryan C., Ganesh, Santhi K., Garrett, Michael R., Gopalakrishnan, Kathirvel, Joe, Bina, Lee, Norman H., Luu, Truong V., Manickavasagam, Ezhilarasi, O'Connor, Ashley, Pérusse, Louis, Rankinen, Tuomo, Rao, Dabeeru C., Rapp, John P., Rice, Treva, Saad, Yasser, Toland, Edward J., Weder, Alan B., Yerga-Woolwine, Shane +25 morecore Genomes and phenomes of a population of outbred rats and its progenitors [PDF]
, 2014 Finding genetic variants that contribute to phenotypic variation is one of the main challenges of modern genetics. We used an outbred population of rats (Heterogeneous Stock, HS) in a combined sequence-based and genetic mapping analysis to identify ..., Baud, Amelie, Flint, Jonathan, Guryev, Victor, Hummel, Oliver, Johannesson, Martina +5 morecore +3 more sourcesNociceptin attenuates the escalation of oxycodone self-administration by normalizing CeA-GABA transmission in highly addicted rats. [PDF]
, 2020 Approximately 25% of patients who are prescribed opioids for chronic pain misuse them, and 5 to 10% develop an opioid use disorder. Although the neurobiological target of opioids is well known, the molecular mechanisms that are responsible for the ...Carrette, Lieselot LG, de Guglielmo, Giordano, George, Olivier, Kallupi, Marsida, Kononoff, Jenni, Palmer, Abraham A, Schweitzer, Paul, Solberg Woods, Leah C +7 morecore Molecular targets of alcohol action: translational research for pharmacotherapy development and screening. [PDF]
, 2011 Alcohol abuse and dependence are multifaceted disorders with neurobiological, psychological, and environmental components. Research on other complex neuropsychiatric diseases suggests that genetically influenced intermediate characteristics affect the ...Addolorato, Alexander-Kaufman, Alte, American Psychiatric Association, Anni, Anton, Anton, Anton, Arkin, Arlinde, Aschner, Atz, Barr, Beck, Beck, Belknap, Bell, Bell, Bell, Bemeur, Bendroth, Bennett, Bennett, Bergeson, Bertsch, Bhardwaj, Bhave, Bierut, Blalock, Blednov, Blizard, Borucki, Bosch-Morell, Brodin, Buck, Bueno, Bull, Butterworth, Butterworth, Caberlotto, Caspi, Chatterjee, Chester, Chi, Ciccocioppo, Cloninger, Colantuoni, Colombo, Colombo, Cotton, Cozzoli, Crabbe, Crabbe, Crabbe, Crabbe, Crabbe, Crabbe, Crabbe, Crabbe, D'Souza, Daniels, Davies, Davis, Deken, Demarest, Dev, Dick, Dick, Dick, Dick, Duranceaux, Dutta, Edenberg, Edenberg, Edenberg, Edenberg, Ehlers, Erblich, Eriksson, Eriksson, Etheridge, Evans, Fehr, Fehr, Flatscher-Bader, Foroud, Franke, Freeman, Freeman, Fukuda, Garbutt, Garbutt, Garner, Gelernter, Geschwind, Godefroy, Goldman, Golka, Gorini, Gottesman, Griffiths-Jones, Hariri, Haroutunian, Harper, Harper, Hashimoto, Hassan, Heilig, Heilig, Helander, Higuchi, Hillemacher, Hinckers, Hirano, Hock, Hodge, Hoffman, Hoiseth, Hollander, Hommer, Hood, Hu, Huntley, Husi, Iwamoto, Iwamoto, Jackson, Johnson, Johnson, Johnson, Jones, Kashem, Kashem, Kasinathan, Kaur, Kawahara, Kemming, Kendler, Kerns, Kim, Kimpel, Kissack, Koch, Konkimalla, Koob, Koob, Koob, Kril, Kril, Kurose, Landgraf, Lappalainen, Lavoie, Le, Lea, Lee, Leeman, Leggio, Leggio, Leggio, Leggio, Leggio, Lewohl, Lewohl, Li, Li, Litten, Liu, Liu, Liu, Lock, Loring, Lu, Ludvig, Luthar, Mackay, MacLaren, Maiya, Maiya, Mane, Mann, Marcotte, Mardones, Matsuda-Matsumoto, Matsumoto, Matsumoto, Maycox, Mayfield, Mayfield, Mayfield, McBride, McBride, McBride, McClearn, McClearn, Melo, Merikangas, Merikangas, Miller, Milner, Miranda, Mirin, Mirnics, Mirnics, Mirnics, Mitchell, Mochly-Rosen, Montoliu, Moore, Mor, Morin, Morozova, Mortazavi, Mulligan, Murphy, Murphy, Muth, Nagy, Nestler, Neuhold, Niemela, Noble, Norenberg, Obara, Okutsu, Papagiannakopoulos, Petkov, Pfefferbaum, Phillips, Pietrzykowski, Pongrac, Pragst, Purcell, Quintanilla, Rahman, Ramani, Ratti, Rausch, Reynaud, Rhodes, Richter, Rimondini, Risinger, Roberts, Rodd, Rodd, Rodgers, Rogers, Rounsaville, Saba, Saito, Saito, Sakai, Sathyan, Scheiffele, Schuckit, Schuckit, Schuckit, Schuckit, Schuckit, Schuckit, Shen, Sher, Slutske, Smith, Sokolov, Sommer, Spanagel, Spanagel, Staub, Stephens, Sullivan, Sung, Swift, Swift, Szumlinski, Szumlinski, Tabakoff, Tabakoff, Tabakoff, Tang, Tang, Taracha, Tarantino, Taxman, Thibault, Thiele, Tkachev, Tomita, Treadwell, Vergne, Vetulani, Volavka, Volkow, Wahlsten, Wall, Walter, Wand, Weinshenker, Whitfield, Williams, Winokur, Worst, Wu, Wurst, Wurst, Xu, Yao, Yoneyama, Zembutsu +309 morecore +1 more sourceGenetic Influences on Brain Gene Expression in Rats Selected for
Tameness and Aggression
, 2014 Inter-individual differences in many behaviors are partly due to genetic
differences, but the identification of the genes and variants that influence
behavior remains challenging.Alexander Cagan, Belyaev, Darvasi, Enrico Petretto, Frank W. Albert, François Besnier, Henrike O. Heyne, Irina Z. Plyusnina, Leonid Kruglyak, Lyudmila Trut, Maxime Rotival, Rimma Kozhemyakina, Ronald Nelson, Susann Lautenschläger, Svante Pääbo, Torsten Schöneberg, Örjan Carlborg +16 morecore +1 more sourceReduced Levels of mGlu2 Receptors within the Prelimbic Cortex Are Not Associated with Elevated Glutamate Transmission or High Alcohol Drinking [PDF]
, 2017 Background
A Grm2 cys407* stop codon mutation, which results in a loss of the metabotropic glutamate 2 (mGlu2) receptor protein, was identified as being associated with high alcohol drinking by alcohol-preferring (P) rats.Bell, Richard L., Ding, Zheng-Ming, Hauser, Sheketha R., Ingraham, Cynthia M., Lasek, Amy W., McBride, William J. +5 morecore +1 more source
