Mortality and Neurodevelopmental Outcome in an Italian Cohort of Very Low Birth Weight Infants
ABSTRACT Aim Preterm infants face high risks of mortality and neurodevelopmental impairment. We aimed to evaluate the outcomes in an Italian cohort of very low birth weight infants. Methods This multicenter prospective study included very low birth weight infants born in Italy between 2016 and 2020. Severe functional disability was defined as cognitive
Licia Lugli +28 more
wiley +1 more source
The calcilytic agent NPS 2143 rectifies hypocalcemia in a mouse model with an activating calcium-sensing-receptor (CaSR) mutation:relevance to autosomal dominant hypocalcemia type 1 (ADH1) [PDF]
Autosomal dominant hypocalcemia type 1 (ADH1) is caused by germline gain-of-function mutations of the calcium-sensing receptor (CaSR) and may lead to symptomatic hypocalcemia, inappropriately low serum parathyroid hormone (PTH) concentrations and ...
Allen M. Spiegel +44 more
core +1 more source
The Concise Guide to PHARMACOLOGY 2025/26: Enzymes
The Concise Guide to Pharmacology 2025/26 marks the seventh edition in this series of biennial publications in the British Journal of Pharmacology. Presented in landscape format, the guide provides a comparative overview of the pharmacology of drug target families. The concise nature of the Concise Guide refers to the style of presentation, being clear,
Stephen P. H. Alexander +31 more
wiley +1 more source
Sex differences in primary hypertension [PDF]
Men have higher blood pressure than women through much of life regardless of race and ethnicity. This is a robust and highly conserved sex difference that it is also observed across species including dogs, rats, mice and chickens and it is found in ...
Kathryn Sandberg, Hong Ji
core +1 more source
Fine mapping of bone structure and strength QTLs in heterogeneous stock rat [PDF]
We previously demonstrated that skeletal structure and strength phenotypes vary considerably in heterogeneous stock (HS) rats. These phenotypes were found to be strongly heritable, suggesting that the HS rat model represents a unique genetic resource for
Alam, Imranul +16 more
core +1 more source
Genetic Influences on Brain Gene Expression in Rats Selected for Tameness and Aggression
Inter-individual differences in many behaviors are partly due to genetic differences, but the identification of the genes and variants that influence behavior remains challenging.
Alexander Cagan +16 more
core +1 more source
FK506 suppression of heart and liver allograft rejection: II: The induction of graft acceptance in rats [PDF]
Lewis recipients of orthotopic ACI livers had permanent graft acceptance induced with 3 doses of i.m. FK506 in the early postoperative period. They were studied 100 and 300 days posttransplantation.
Cramer, DV +5 more
core +1 more source
Nociceptin attenuates the escalation of oxycodone self-administration by normalizing CeA-GABA transmission in highly addicted rats. [PDF]
Approximately 25% of patients who are prescribed opioids for chronic pain misuse them, and 5 to 10% develop an opioid use disorder. Although the neurobiological target of opioids is well known, the molecular mechanisms that are responsible for the ...
Carrette, Lieselot LG +7 more
core
The role of the tachykinin NK1 receptor in airway changes in a mouse model of allergic asthma [PDF]
A
De Swert, Katelijne +3 more
core +2 more sources
Identification of HMCES as the Core Genetic Determinant Underlying the <i>xhs1</i> Radiosensitivity Locus in LEA/LEC Rats. [PDF]
Hishida E +7 more
europepmc +1 more source

