Results 81 to 90 of about 7,063 (108)

Benefits of sacubitril/valsartan alone and in combination with dapagliflozin in a preclinical female model of cardiometabolic and age-related cardiac dysfunction. [PDF]

Cardiovasc Diabetol
Mele E, Riemma MA, Donniacuo M, Telesca M, Sorrentino G, D'Amario D, Scialò F, Cianflone E, Cappetta D, Torella D, Castaldo G, Rossi F, Berrino L, Urbanek K, De Angelis A.   +14 more
europepmc   +1 more source

Adolescent intermittent ethanol exacerbates amyloid-β with age in the dorsal hippocampus of female TgF344-AD rats. [PDF]

J Alzheimers Dis
Day SM, Reitz NL, Savage LM.
europepmc   +1 more source

Fibrotic pulmonary dust foci is an advanced pneumoconiosis lesion in rats induced by titanium dioxide nanoparticles in a 2-year inhalation study. [PDF]

Part Fibre Toxicol
Yamano S, Umeda Y.
europepmc   +1 more source

Aberrant Medial Prefrontal Cortex Activity and Flexible Behavior in the TgF344-AD Rat Model of Alzheimer's Disease. [PDF]

J Neurosci
Sloand TJ, Dunham BP, Niedringhaus M, West EA.   +3 more
europepmc   +1 more source

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Efficient collection and cryopreservation of embryos in F344 strain inbred rats

Cryobiology, 2013
In rats, it is now possible to produce genetically engineered strains, not only as transgenic animals but also using gene knockout techniques. Reproductive technologies have been used as indispensable tools to produce and maintain these novel valuable strains.
Takehito Kaneko
exaly   +3 more sources

The LEXF: A new set of rat recombinant inbred strains between LE/Stm and F344

Mammalian Genome, 1997
A new set of rat RI strains consisting of 11 independent strains and 13 of their substrains was established by inbreeding F2 rats between F344/DuCrj and LE/Stm. The strain distribution pattern was examined for 66 microsatellite loci, 8 biochemical genetic markers, 2 histocompatibility loci, and 2 coat color genes.
Jun-Ichi Tanuma, Hiroshi Hiai, Hideki Katoh   +2 more
exaly   +3 more sources

Comparison of energy balance in two inbred strains of rats: Fischer F344 prone to obesity and Lou rats resistant to obesity

Physiology and Behavior, 2006
This study aimed to compare energy balance, metabolic profiles and body composition between two inbred strains of rats (F344 and Lou) submitted to a self-selecting macronutrient. During the 3 weeks of experiment, the two strains did not differ significantly for their total energy intake; males: F344 = 5875.4 +/- 171.4 kJ, Lou = 5619.2 +/- 349.4 kJ; and
Marc Goubern, Christiane Larue-Achagiotis   +1 more
exaly   +5 more sources

Cocaine self-administration and locomotor activity are altered in Lewis and F344 inbred rats by RTI 336, a 3-phenyltropane analog that binds to the dopamine transporter

Brain Research, 2005
Lewis and Fischer 344 (F344) rats differ in responses to cocaine and characteristics of the mesolimbic dopamine system. Compared to F344 rats, Lewis rats have lower D2 receptor and dopamine transporter (DAT) levels in nucleus accumbens (NAc). We showed previously that altering D1 and D2 receptor levels pharmacologically had strain-dependent effects on ...
Colin N. Haile, Frank Ivy Carroll, Therese A Kosten   +2 more
exaly   +3 more sources

Genetic and Cellular Factors in the Immune Response. III. The Cellular Response to Poly(Glu52Lys33Tyr15) in the Highly Responding ACI and Poorly Responding F344 Strains of Inbred Rats

Journal of Immunology, 1971
Abstract The antibody response in the inbred rat is controlled by at least two autosomal genes; in addition, there is a sex influence which may include both additional genetic factors and environmental influences (1–3). We postulate that one of the major genes controlling the antibody response influences the size of the cell population ...
Ronald N. Germain, T J Gill, Thomas J Gill   +2 more
exaly   +2 more sources