BioMed Research International, Volume 2024, Issue 1, 2024.Aim: This systematic review was aimed at addressing the focused question: What is the protective potential of biological agents against alveolar bone resorption during the progression of experimental periodontitis (EP)? Material and Methods: The study protocol was registered in the Open Science Framework database (doi:10.17605/OSF.IO/3P2HY).
Gabriela Ezequiel Oliveira +9 more
wiley +1 more source
Stability of small non-coding RNA reference gene expression in the rat retina during exposure to cyclic hyperoxia [PDF]
, 2013 Purpose: Oxygen-induced retinopathy (OIR) is a robust animal model of human retinopathy of prematurity that readily allows changes in retinal gene and microRNA (miRNA) expression in response to fluctuations in oxygen levels to be studied.
Brereton, Helen Mary +3 more
core
Macrophages and Galectin 3 Control Bacterial Burden in Acute and Subacute Murine Leptospirosis That Determines Chronic Kidney Fibrosis [PDF]
, 2018 Previous studies have suggested that macrophages may contribute to acute Leptospira dissemination, as well as having a major role in kidney fibrosis. Our aim was to characterize the role of macrophages and galectin 3 (Gal-3) on the survival, clinical ...
Carrera Silva, Eugenio Antonio +10 more
core +3 more sources
Cerebellar output controls generalized spike-and-wave discharge occurence [PDF]
, 2015 © 2015 The Authors Annals of Neurology published by Wiley Periodicals, Inc. on behalf of American Neurological Association. This is an open access article under the terms of the Creative Commons Attribution-NonCommercial-NoDerivs License (CC BY-NC-ND 4.0)
Alva, Parimala +15 more
core +5 more sources
Genomic and non-genomic regulation of PGC1 isoforms by estrogen to increase cerebral vascular mitochondrial biogenesis and reactive oxygen species protection [PDF]
, 2014 We previously found that estrogen exerts a novel protective effect on mitochondria in brain vasculature. Here we demonstrate in rat cerebral blood vessels that 17beta-estradiol (estrogen), both in vivo and ex vivo, affects key transcriptional ...
C. Stirone +4 more
core +4 more sources
How age, sex and genotype shape the stress response [PDF]
, 2016 Exposure to chronic stress is a leading pre-disposing factor for several neuropsychiatric disorders as it often leads to maladaptive responses. The response to stressful events is heterogeneous, underpinning a wide spectrum of distinct changes amongst ...
Aisa +201 more
core +2 more sources
Enhanced hippocampal long-term potentiation and spatial learning in aged 11ß-hydroxysteroid dehydrogenase type 1 knock-out mice [PDF]
, 2007 Glucocorticoids are pivotal in the maintenance of memory and cognitive functions as well as other essential physiological processes including energy metabolism, stress responses, and cell proliferation.
Brownstein, D. +9 more
core +2 more sources
Effect of Gsk3 inhibitor CHIR99021 on aneuploidy levels in rat embryonic stem cells [PDF]
, 2014 Germline competent embryonic stem (ES) cells can serve as a tool to create genetically engineered rat strains used to elucidate gene function or provide disease models.
Anagha S. Bock +2 more
core +1 more source
Positional identification and functional analysis of genes regulating autoimmune arthritis [PDF]
, 2016 The major histocompatibility complex (MHC) is the most gene-dense and polymorphic region in the human genome with strong associations to many autoimmune disorders, including rheumatoid arthritis (RA).
Yau, Anthony Chun Yeung
core +1 more source