Results 21 to 30 of about 3,551 (111)
Arquivos Brasileiros de Cardiologia, 2007 OBJETIVO: O objetivo deste estudo foi avaliar a reparação óssea em ratos espontaneamente hipertensos (SHR) e compará-la com a de ratos normotensos, avaliando machos e fêmeas.
Andresa Costa Pereira +4 more
doaj +1 more source
Disease Models & Mechanisms, 2016 The Wistar Kyoto (WKY) rat and the spontaneously hypertensive (SHR) rat inbred strains are well-established models for human crescentic glomerulonephritis (CRGN) and metabolic syndrome, respectively.
Ana Isabel Garcia Diaz +6 more
doaj +1 more source
Effects of early life trauma are dependent on genetic predisposition: a rat study
Behavioral and Brain Functions, 2011 Background Trauma experienced early in life increases the risk of developing a number of psychological and/or behavioural disorders. It is unclear, however, how genetic predisposition to a behavioural disorder, such as attention-deficit/hyperactivity ...
Russell Vivienne A +2 more
doaj +1 more source
The Journal of Physiology, EarlyView.Abstract figure legend Overview of cerebral small vessel disease (cSVD) pathophysiology and current modelling challenges. Left: clinical burden and key unresolved research questions. Right: neurovascular unit (NVU) architecture highlighting sites of cSVD pathology across arterioles, capillaries and venules, including interactions between endothelial ...
Sophie Beaumont +3 more
wiley +1 more source
Disease Models & Mechanisms, 2017 We previously mapped hypertension-related insulin resistance quantitative trait loci (QTLs) to rat chromosomes 4, 12 and 16 using adipocytes from F2 crosses between spontaneously hypertensive (SHR) and Wistar Kyoto (WKY) rats, and subsequently identified
Philip M. Coan +9 more
doaj +1 more source
Reduced Dietary Protein Induces Changes in the Dental Proteome
Journal of Experimental Zoology Part B: Molecular and Developmental Evolution, Volume 346, Issue 2, Page 107-127, March 2026.Low dietary protein (10%) from normal (20%) does change protein expression in tooth proteome and alter developmental pathways. Among the significant protein expressions changes are actin‐based myosins, tooth, and bone development proteins. Perplexingly tooth size is not altered, suggesting more nuanced phenotypic response to low dietary protein in ...
Robert W. Burroughs +2 more
wiley +1 more source
Von Willebrand Factor Gene Variants Associate with Herpes simplex Encephalitis.
PLoS ONE, 2016 Herpes simplex encephalitis (HSE) is a rare complication of Herpes simplex virus type-1 infection. It results in severe parenchymal damage in the brain.
Nada Abdelmagid +20 more
doaj +1 more source
Journal of Cellular and Molecular Medicine, Volume 29, Issue 23, December 2025.ABSTRACT Endoplasmic reticulum stress (ERS) emerges as a critical pathophysiological nexus in hypertension and related cardiovascular diseases. Chronic ERS activation via the IRE1α‐XBP1, ATF6, and PERK pathways drives vascular endothelial dysfunction (reduced NO bioavailability, increased ET‐1), renin‐angiotensin system (RAS) hyperactivation ...
Xin Ma +6 more
wiley +1 more source
Chemistry &Biodiversity, Volume 22, Issue 9, September 2025.ABSTRACT The subfamily Gomphrenoideae is composed of about 480 accepted species, many of which have been historically used as medicinal plants, reason why they have been studied in terms of chemical profile, biological activity, and safety. This review consolidates the advances in research on this subfamily over the past 47 years, emphasizing its ...
Dayanna Isabel Araque Gelves +3 more
wiley +1 more source