Results 31 to 40 of about 3,551 (111)
In the current research, an optimized ultrasound‐assisted extraction method was developed for extracting anthocyanin from Berberis kaschgarica Rupr. fruits. The extract was purified and its effects were evaluated against hypertension in the rat model. The developed UAE method was found suitable for high‐yield anthocyanin extraction.
Nawaz Khan +10 more
wiley +1 more source
Re‐evaluation of saccharin and its sodium, potassium and calcium salts (E 954) as food additives
Abstract This opinion deals with the re‐evaluation of saccharin and its sodium, potassium and calcium salts (E 954) as food additives. Saccharin is the chemically manufactured compound 1,2‐benzisothiazol‐3(2H)‐one‐1,1‐dioxide. Along with its sodium (Na), potassium (K) and calcium (Ca) salts, they are authorised as sweeteners (E 954).
EFSA Panel on Food Additives and Flavourings (FAF) +42 more
wiley +1 more source
We aimed at assessing anxiety‐ and depressive‐like behaviors in Wistar‐Kyoto (WKY) rats and determining whether these were associated to changes in levels of neuroinflammatory markers (Iba‐1, CD86, Ym1, GFAP, S100A10) and mediators (interleukins IL‐1β, IL‐6, TNF‐α) in the prefrontal cortex (PFC), hippocampus, and amygdala.
Miguel Farinha‐Ferreira +5 more
wiley +1 more source
Spontaneous vascular dysfunction in Dahl salt‐sensitive male rats raised without a high‐salt diet
Abstract Dahl salt‐sensitive (SS) rats fed a high‐salt diet, but not low‐salt, exhibit vascular dysfunction. Several substrains of SS rats exist that differ in their blood pressure phenotypes and salt sensitivity. The goal of this study was to investigate whether the John‐Rapp‐derived SS rat (SS/Jr), which exhibits spontaneous hypertension on a low ...
Arturo Grano de Oro +5 more
wiley +1 more source
Abstract Taking into account homeostatic disorders resulting from arterial hypertension and the key importance of CacyBP/SIP, β‐catenin and endocannabinoids in the functioning of many organs, it was decided to assess the presence and distribution of CacyBP/SIP, β‐catenin, CB1 and CB2 in the adrenal glands of hypertensive rats of various aetiology.
Magdalena Smereczańska +3 more
wiley +1 more source
Abstract The spontaneously hypertensive rat (SHR) is a selectively bred animal strain that is frequently used to model attention‐deficit hyperactivity disorder (ADHD) because of certain genetically determined behavioural characteristics. To test the hypothesis that the characteristically altered response to positive reinforcement in SHRs may be due to ...
Yu‐Ting Li +4 more
wiley +1 more source
British Journal of Haematology, Volume 207, Issue 2, Page 631-635, August 2025.
Thomas Altmann +11 more
wiley +1 more source
Using the Hybrid Rat Diversity Panel, we demonstrated that sex and genetic background confer differences in mechanical sensitivity, thermal sensitivity, and oxycodone‐induced analgesia. Created with BioRender.com. Abstract Opioid use disorder (OUD) is an ongoing public health concern in the United States, and relatively little work has addressed how ...
Eamonn P. Duffy +7 more
wiley +1 more source

