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Screening of inbred rat strains for electrophoretic protein polymorphisms
Biochemical Genetics, 1978Nineteen inbred strains of the laboratory rat (Rattus norvegicus) were investigated for genetic differences by starch and agarose gel electrophoretic techniques. For six out of 21 loci, interstrain differences were observed: Tf, 6PGD, Es-1, Es-4, Es-5, and Svp. The variants are briefly described and the allelic distributions are tabulated.
E. Günther, Klaus Bender
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Allotypic Specificity of Serum Protein in Inbred Strains of Rats
Nature, 1967SINCE Oudin's original discovery of allotypes in the rabbit1 a similar genetically determined intra-species differentiation of plasma proteins has been described in several species2. Although most interest was concentrated on immunoglobulins, allotypy is clearly a general biological phenomenon.
Barabas, A Z, Kelus, A S
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Strain differences in inbred rats: influence of strain and diet on haematological traits
Laboratory Animals, 19835 inbred strains of rats maintained on 3 commercial pelleted diets were investigated for differences in haematological traits on the 154th day of age. Number, size and haemoglobin content of the erythrocytes were shown to be strongly influenced by strain and diet.
Hansjoachim Hackbarth +2 more
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Efficient collection and cryopreservation of embryos in F344 strain inbred rats
Cryobiology, 2013In rats, it is now possible to produce genetically engineered strains, not only as transgenic animals but also using gene knockout techniques. Reproductive technologies have been used as indispensable tools to produce and maintain these novel valuable strains.
Takehito Kaneko, Hiroaki Taketsuru
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The response of three inbred strains of rat to the carcinogen 1,2-dimethylhydrazine
Pathology, 1981Rats of 3 inbred strains (DA, HS and AS2) were dosed with 1,2-dimethylhydrazine 2HCl (DMH) or saline by gavage weekly for 10 wk. DA and HS rats showed little overt toxic reaction but all AS2 rats died following DMH doses of 30 mg/kg. However, at 10 mg/kg 60% of AS2 rats survived the 30 wk experiment. All DA rats developed a high yield of adenocarcinoma
Clinton A. Teague +2 more
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Differences in Kindling Development in Seven Outbred and Inbred Rat Strains
Experimental Neurology, 1998The kindling phenomenon, i.e., the progressive development of focal and secondarily generalized seizures upon repeated electrical stimulation of a limbic brain region, occurs in various species, but with marked differences in kindling rate between species and also within the same species. In rats, differences in kindling rates have been reported within
Wolfgang Löscher +2 more
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Correlative Analysis of Ethanol‐Related Phenotypes in Rat Inbred Strains
Alcoholism: Clinical and Experimental Research, 1984As a summary presentation of the ethanol‐related traits in the rat inbred strains, the responses to ethanol for various traits of the eight strains were analyzed. The intercorrelations among the means of the strains were computed and the interrelationships among the strain con‐elations were determined further by partial correlation and factor analysis.
Richard A. Deitrich, Karen P. Spuhler
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Two Inbred Rat Strains That Differ Substantially in Hip Fragility
Calcified Tissue International, 2003One approach to identifying the genetic influences on skeletal phenotypes involves the creation and genetic mapping of a population of the second filial (F2) offspring derived from a cross of two inbred strains of rodents. The two inbred strains should be chosen based upon a large difference in the phenotype of interest, e.g., bone fragility.
Qiwei Sun, Charles H. Turner
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Alcoholism: Clinical and Experimental Research, 1987
M. Palmer +3 more
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M. Palmer +3 more
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