Results 51 to 60 of about 3,076 (133)

Validação farmacológica de um novo modelo comportamental integrado de ansiedade/emocionalidade em ratos [PDF]

open access: yes, 2012
Dissertação (mestrado) - Universidade Federal de Santa Catarina, Centro de Ciências Biológicas, Programa de Pós-Graduação em Farmacologia, Florianópolis, 2010Vários testes existem para medir comportamentos relacionados à ansiedade em roedores de ...
Wehrmeister, Thaize Debatin
core  

Experimental autoimmune glomerulonephritis (EAG) induced by homologous and heterologous glomerular basement membrane in two substrains of Wistar-Kyoto rat

open access: yes, 1998
Background, Goodpasture's, or antiglomerular basement membrane (GBM), disease presents with rapidly progressive glomerulonephritis, and is caused by autoimmunity to the NC1 domain of the α3 chain of type IV collagen.
Cashman, Stephen J.   +4 more
core   +1 more source

Strain differences in self-administration of methylphenidate and sucrose pellets in a rat model of attention-deficit hyperactivity disorder

open access: yes, 2011
Despite its abuse potential, methylphenidate (MPH) is widely prescribed for treatment of attention-deficit hyperactivity disorder (ADHD). The purpose of the present study was to examine MPH self-administration in a rat model of ADHD.
Cassandra D. Gipson   +9 more
core   +1 more source

Heterogeneous stock rat: a unique animal model for mapping genes influencing bone fragility.

open access: yes, 2011
Previously, we demonstrated that skeletal mass, structure and biomechanical properties vary considerably among 11 different inbred rat strains. Subsequently, we performed quantitative trait loci (QTL) analysis in four inbred rat strains (F344, LEW, COP ...
Turner, Charles H.   +62 more
core   +1 more source

Genotype-dependent responsivity to inflammatory pain: the role of TRPV1 in the periaqueductal grey

open access: yes, 2016
The ability to experience pain is essential for survival, and to prevent potential tissue damage upon exposure to noxious stimuli. The periaqueductal grey - rostral ventromedial medulla – dorsal horn of the spinal cord (PAG-RVM-DH) pathway plays a ...
Madasu, Manish Kumar
core   +1 more source

The role of the endocannabinoid system in the affective modulation of pain

open access: yes, 2015
Pain represents a major unmet clinical need and affects a large number of individuals worldwide. Numerous studies indicate a very high prevalence of chronic pain comorbid with psychiatric disorders such as anxiety and depression.
Jennings, Elaine
core   +1 more source

Efeito ansiogênico da substância P :: envolvimento do óxido nítrico / [PDF]

open access: yes, 1998
Dissertação (Mestrado) - Universidade Federal de Santa Catarina, Centro de Ciências ...
Baretta, Irinéia Paulina
core  

Identification of genetic loci involved in diabetes using a rat model of depression.

open access: yes, 2009
While diabetic patients often present with comorbid depression, the underlying mechanisms linking diabetes and depression are unknown. The Wistar Kyoto (WKY) rat is a well-known animal model of depression and stress hyperreactivity.
Kazuhiro Shimomura   +19 more
core   +1 more source

Genetic map of seven polymorphic markers comprising a single linkage group on rat Chromosome 5

open access: yes, 1993
Seven polymorphic markers comprising a single linkage group were assigned to rat Chromosome (Chr) 5 by linkage analysis of the progeny of an F2 intercross of Fischer (F344/N) and Lewis (LEW/N) inbred rats.
Zha, Hongbin   +13 more
core   +1 more source

Lineage is an epigenetic modifier of QTL influencing behavioral coping with stress.

open access: yes, 2005
A genome-wide scan was carried out on a segregating F2 population of rats derived from reciprocal intercrosses between two inbred strains of rats, Fisher 344 (F344) and Wistar Kyoto (WKY) that differ significantly in their behavioral coping responses ...
Baum, A E   +6 more
core  

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