Results 281 to 290 of about 448,712 (333)

Recent advances in animal models for pathological scar research: A comprehensive review of experimental approaches and translational relevance

open access: yesAnimal Models and Experimental Medicine, EarlyView.
Animal models remain indispensable in the study of pathological scars, each offering unique advantages and constraints. Their integration with in vitro and ex vivo systems is key to developing personalized, clinically translatable antifibrotic therapies. Abstract Pathological scarring, manifested in the form of hypertrophic scars (HTS) and keloid scars
Diana‐Larisa Ancuța   +3 more
wiley   +1 more source

Behavioral heterogeneity in Sprague-Dawley rats

Physiology & Behavior, 1992
Because of consistent individual differences in animal behavior, it is often difficult to interpret experimental data. We therefore attempted to rank Sprague Dawley rats by a hierarchical ascendant clustering technique using data from avoidance conditioning and open-field testing (scores of exploratory activity before, during, and after an ...
M, Curé, J P, Rolinat
openaire   +2 more sources

Spontaneous Hibernomas in Sprague-Dawley Rats

Toxicologic Pathology, 2009
Hibernomas are rare neoplasms originating in brown adipose tissue of humans and other animal species, including laboratory animals. Background incidence values for these tumors in all common strains of laboratory rats are generally accepted as being <0.1%.
Richard H, Bruner   +10 more
openaire   +2 more sources

Postirradiation Sarcomas in Sprague-Dawley Rats

Radiation Research, 1998
A series of radiation-induced neoplasms occurred in Sprague-Dawley rats 4-8 months after irradiation of a single hind leg with 60Co gamma rays. The rats were exposed to fractionated cumulative doses that ranged from 0 to 106 Gy. Osteosarcomas, malignant fibrous histiocytomas and fibrosarcomas developed in the radiation fields of a number of the rats in
P T, Tinkey   +5 more
openaire   +2 more sources

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