Results 1 to 10 of about 246,656 (307)

Polysorbate 20 increases oral absorption of digoxin in wild-type Sprague Dawley rats, but not in mdr1a(-/-) Sprague Dawley rats

International Journal of Pharmaceutics, 2016
The aim was to investigate the ability of polysorbate 20 to alter oral digoxin absorption in vitro and drug exposure in vivo via modulation of transporter mediated efflux. Transport studies were performed in MDCKII-MDR1 and Caco-2 cells using 3H-digoxin.
Carsten Uhd Nielsen, René Holm
exaly   +2 more sources

Immunolocalization of Ghrelin in the Stomach of Sprague‐Dawley Rat

Anatomia, Histologia, Embryologia, 2010
With 3 figures and 1 tableSummaryTo investigate the distribution of ghrelin in different regions of stomach in Sprague‐Dawley rat, and attempt to compare with those of humans and other mammalian species in this study, the stomach of rats was divided into five sections, cardia, fundus, greater curvature, lesser curvature and pylorus ...
J, Li, S-Q, Yi, H-X, Wang, N, Yi, Y, Ogawa, N, Ozaki, M, Itoh   +6 more
openaire   +2 more sources

Carcinogenic Effects of Diisopropanolnitrosamine in Sprague-Dawley Rats

JNCI: Journal of the National Cancer Institute, 1977
The carcinogenic effects of diisopropanolinitrosamine (DIPN) were tested in Sprague-Dawley rats and were then compared with results produced earlier by the same substance in Syrian hamsters. In addition to the similarities, several differences were noted; for example, DIPN caused pancreatic tumors in all the hamsters, but only 1 pancreatic tumor was ...
U, Mohr, G, Reznik, P, Pour
openaire   +2 more sources

Normal colon of Sprague-Dawley rats

Anatomy and Embryology, 1992
The patterns of expression of the human-tumor-associated antigens, CO17-1A, GA73-3, BR55-2, GICA19-9, CA50 and carcino-embryonic antigen (CEA) were studied in the normal colonic mucosa (the last three also in the serum) of Sprague-Dawley rats. Four immunohistochemically different segments were identified: caecum, ascending colon, transverse colon and ...
J D, Shetye, C A, Rubio, H T, Mellstedt
openaire   +2 more sources

Lactational transfer of bisphenol A in Sprague–Dawley rats

Toxicology Letters, 2010
Bisphenol A (BPA), an important industrial chemical to which humans are exposed on a daily basis, has long been associated with endocrine disruption in experimental animal models. Such exposures are of concern, particularly during fetal and early neonatal periods, because of greater vulnerability of developing organs to aberrant endocrine signaling ...
Daniel R, Doerge, Michelle, Vanlandingham, Nathan C, Twaddle, K Barry, Delclos   +3 more
openaire   +2 more sources

Exosomes from dysfunctional chondrocytes affect osteoarthritis in Sprague-Dawley rats through FTO-dependent regulation of PIK3R5 mRNA stability

Bone and Joint Research, 2022
Guohua Lv, Haoyu He, Lei Kuang
exaly  

Incidences and Range of Spontaneous Microscopic Lesions in the Eye of Sprague-Dawley Rats and Han Wistar Rats Used in Toxicity Studies

Toxicologic Pathology, 2021
Emilie Cloup, Vasanthi Mowat
exaly  

Maternal toxicity of methacrylonitrile in Sprague-Dawley rats

Bulletin of Environmental Contamination and Toxicology, 1992
M Y, Farooqui, M I, Villarreal
openaire   +2 more sources

Spontaneous Neoplastic Lesions in Aged Sprague-Dawley Rats.

Experimental Animals, 2001
K Iwakura, N Sumi
exaly  

Age-related Changes in Thyroid Structure and Function in Sprague-Dawley Rats

Veterinary Pathology, 1992
R Heywood
exaly