Results 1 to 10 of about 64,708 (159)

Role of plasma neuropeptide Y in acute myocardial infarction: a case-control study [PDF]

BMC Cardiovascular Disorders
Background As neuropeptide Y is associated with endothelial dysfunction, this study explored the relationship between neuropeptide Y and acute myocardial infarction. Methods We included 128 acute myocardial infarction cases and 62 controls.
Yan-li Zheng, Hui-li Lin, Yue-ting Li, Mei-mei Li, Jing-ru Du, Wan-da Wang, Yao-guo Wang, Yin-lian Cai   +7 more
doaj   +2 more sources

Regulation of Feeding and Metabolism by Neuropeptide F and Short Neuropeptide F in Invertebrates

Frontiers in Endocrinology, 2019
Numerous neuropeptide systems have been implicated to coordinately control energy homeostasis, both centrally and peripherally. However, the vertebrate neuropeptide Y (NPY) system has emerged as the best described one regarding this biological process ...
Liesbet Temmerman, Isabel Beets, Sven Zels   +2 more
exaly   +3 more sources

Neuropeptide Y in first-episode schizophrenia: is there any sex differences in the pathogeneses of schizophrenia? [PDF]

Frontiers in Psychiatry
ObjectiveThis study investigated relationships between Neuropeptide Y levels and severity of psychiatric symptoms in first-episode schizophrenia patients, and explore the sexual heterogeneity in them.MethodsWe recruited 115 first-episode schizophrenia ...
Jia-Qi Song, Wen Xin, Jian-Jin Yu, Qing Zhao, Hong-Na Li, Da-Chun Chen   +5 more
doaj   +2 more sources

Overexpression of neuropeptide Y decreases responsiveness to neuropeptide Y [PDF]

Neuropeptides, 2020
Neuropeptide Y (NPY) is an endogenous neuropeptide that is abundantly expressed in the central nervous system. NPY is involved in various neurological processes and neuropsychiatric disorders, including fear learning and anxiety disorders. Reduced levels of NPY are reported in Post-Traumatic Stress Disorder (PTSD) patients, and NPY has been proposed as
Katelynn M, Corder, Qin, Li, Mariana A, Cortes, Aundrea F, Bartley, Taylor R, Davis, Lynn E, Dobrunz   +5 more
openaire   +2 more sources

Neuropeptide Y/Y5 Receptor Pathway Stimulates Neuroblastoma Cell Motility Through RhoA Activation

Frontiers in Cell and Developmental Biology, 2021
Neuropeptide Y (NPY) has been implicated in the regulation of cellular motility under various physiological and pathological conditions, including cancer dissemination. Yet, the exact signaling pathways leading to these effects remain unknown.
Nouran Abualsaud, Nouran Abualsaud, Nouran Abualsaud, Lindsay Caprio, Susana Galli, Ewa Krawczyk, Lamia Alamri, Shiya Zhu, G. Ian Gallicano, Joanna Kitlinska   +9 more
doaj   +1 more source

The Bidirectional Relationship of NPY and Mitochondria in Energy Balance Regulation

Biomedicines, 2023
Energy balance is regulated by several hormones and peptides, and neuropeptide Y is one of the most crucial in feeding and energy expenditure control. NPY is regulated by a series of peripheral nervous and humoral signals that are responsive to nutrient ...
Diana Sousa, Eduardo Lopes, Daniela Rosendo-Silva, Paulo Matafome   +3 more
doaj   +1 more source

Neuropeptide Y regulates proliferation and apoptosis in granulosa cells in a follicular stage-dependent manner

Journal of Ovarian Research, 2020
Background The complex regulatory mechanism involved in ovarian follicular development is not completely understood. Neuronal neuropeptide Y (NPY) is involved in the regulation of feeding behavior, energy homeostasis, and reproduction behavior, while its
Yoko Urata, Reza Salehi, Patricia D. A. Lima, Yutaka Osuga, Benjamin K. Tsang   +4 more
doaj   +1 more source

Unusually persistent Gαi-signaling of the neuropeptide Y2 receptor depletes cellular Gi/o pools and leads to a Gi-refractory state

Cell Communication and Signaling, 2020
Background A sensitive balance between receptor activation and desensitization is crucial for cellular homeostasis. Like many other GPCR, the human neuropeptide Y2 receptor (hY2R) undergoes ligand dependent activation and internalization into ...
Isabelle Ziffert, Anette Kaiser, Stefanie Babilon, Karin Mörl, Annette G. Beck-Sickinger   +4 more
doaj   +1 more source

Neuropeptide Y directly reduced apoptosis of granulosa cells, and the expression of NPY and its receptors in PCOS subjects

Journal of Ovarian Research, 2023
Background Most women with anovulatory infertility show polycystic ovarian syndrome (PCOS), and androgen excess is known as a key factor involved in pathogenicity of PCOS.
Yoko Urata, Reza Salehi, Brandon A. Wyse, Sahar Jahangiri, Clifford L. Librach, Chii-Ruey Tzeng, Yutaka Osuga, Benjamin Tsang   +7 more
doaj   +1 more source

The effect of human wharton’s jelly-derived mesenchymal stem cells on MC4R, NPY, and LEPR gene expression levels in rats with streptozotocin-induced diabetes [PDF]

Iranian Journal of Basic Medical Sciences, 2020
Objective(s): Type 1 diabetes (T1D) is an autoimmune disease resulting from inflammatory destruction of islets β-cells. Nowadays, progress in cell therapy, especially mesenchymal stem cells (MSCs) proposes numerous potential remedies for T1D. We aimed to
Fatemeh Sabet Sarvestani, Mohammad Ali Zare, Forough saki, Farhad Koohpeyma, Ismail H. al-Abdullah, Negar Azarpira   +5 more
doaj   +1 more source