Results 41 to 50 of about 74,318 (299)

New Onset of Fibromyalgia After Exposure to a Combat Environment: A Longitudinal Cohort Study

open access: yesArthritis Care &Research, EarlyView.
Objective Traumatic life events are hypothesized to be triggers for the onset of fibromyalgia. Posttraumatic stress disorder (PTSD) is a common comorbidity of fibromyalgia. However, limited prospective data are available on the development of fibromyalgia after exposure to high‐magnitude stress.
Jay B. Higgs   +15 more
wiley   +1 more source

Characterization of Receptor Types for Neuropeptide Y and Related Peptides

open access: yes
The structurally related peptides neuropeptide Y (NPY), peptide YY (PYY), and pancreatic polypeptide (PP) are neuronal and/ or endocrine messengers that are involved in a variety of physiological processes. NPY and PYY are able to evoke potent biological
Sheikh, Sören P   +2 more
core   +2 more sources

Piezo2 Mediates a Vicious Cycle of “Mechanical Homeostasis Imbalance—Inflammation” in Sensory Nerves and the Cartilage Endplate

open access: yesAdvanced Science, EarlyView.
In a lumbar spine instability model, dorsal root ganglion cells mediate the perception of relevant mechanical stresses through Piezo2 and subsequently release CGRP. CGRP activates the NF‐κB signaling pathway in cartilage endplate cells through the receptor RAMP1.
Hanpeng Xu   +16 more
wiley   +1 more source

Functional Analysis of Ligand‐Gated Chloride Channels in a Cnidarian Sheds Light on the Evolution of Inhibitory Signaling

open access: yesAdvanced Science, EarlyView.
We uncover a large variety of putative inhibitory ligand‐gated ion channels (LGICs) in the phylum Cnidaria, the sister group to all bilaterian animals. Phylogenetic analysis suggests a complex evolutionary history of inhibitory LGICs with diverse neurotransmitter ligands.
Abhilasha Ojha   +13 more
wiley   +1 more source

Relationship between the Production Traits and three Candidate Genes in the Prolactin’s In/Del×In/Del Population of Silkie Fowl

open access: yesThe Journal of Poultry Science, 2014
Silkie fowl are very famous in China and Japan, however the egg production rate of the Silkie fowl is very low because of broodiness. Authors have examined the polymorphisms of the 5′-flanking region of the prolactin gene in Taihe Silkie fowl and ...
MD. Mijanur Rahman   +6 more
doaj   +1 more source

Regulation of neuropeptide Y in body microenvironments and its potential application in therapies: a review

open access: yesCell & Bioscience, 2021
Neuropeptide Y (NPY), one of the most abundant neuropeptides in the body, is widely expressed in the central and peripheral nervous systems and acts on the cardiovascular, digestive, endocrine, and nervous systems.
Yan Zhang   +6 more
doaj   +1 more source

Age-dependent patterns of somatostatinergic neurons in sympathetic paravertebral ganglia

open access: yesСеченовский вестник, 2023
Aim. We aimed to determine the content of neurons expressing somatostatin (SST) and their colocalization with  cells expressing tyrosine hydroxylase (TH) and neuropeptide Y (NPY) in the cranial cervical ganglion (CCG) and celiac  plexus in rats ...
A. I. Emanuilov   +3 more
doaj   +1 more source

Neuropeptide Y in sympathetic co-transmission: recent advances in the search for neuropeptide Y antagonists

open access: yes, 1994
Since the discovery of neuropeptide Y which is co-stored and co-operate with noradrenaline (NA) in sympathetic nerve fibers, several scientific groups have searched for structures with neuropeptide Y antagonistic properties.
Edvinsson, Lars   +7 more
core   +1 more source

A Brain‐Wide Atlas of Astrocytic Oxytocin Receptors Reveals a Glial Basis for Nucleus Accumbens Modulation of Affiliative Behavior

open access: yesAdvanced Science, EarlyView.
The cellular actors of oxytocin signaling are under intense scrutiny. A brain‐wide anatomical and functional analysis in mice and rats reveals widespread expression of oxytocin receptors in astrocytes. These receptors are functionally active and, in the nucleus accumbens, selectively regulate male social affiliation.
Clémence Denis   +32 more
wiley   +1 more source

Evolution of neuropeptide Y/RFamide-like receptors in nematodes

open access: yesHeliyon
The Neuropeptide Y/RFamide-like receptors belong to the Rhodopsin-like G protein-coupled receptors G protein-coupled receptors (GPCRs) and are involved in functions such as locomotion, feeding and reproduction.
Franziska Reinhardt   +3 more
doaj   +1 more source

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