Results 61 to 70 of about 74,318 (299)
Lesion Site‐Targeted Microspheres Modulate Nav1.7‐Related Signaling for Osteoarthritis Treatment
Advanced Science, EarlyView.Cartilage‐targeted carbamazepine‐loaded WYRGRL‐modified composite microspheres (CBZ/WCOM) anchor to exposed type II collagen in osteoarthritic lesions and release carbamazepine under acidic conditions. This bind‐then‐release platform modulates Nav1.7‐related sodium signaling, Na⁺/Ca²⁺ exchanger‐associated Ca2+ dynamics, and heat shock protein 70 ...
Cheng Chen +15 more
wiley +1 more source
Regulation of Energy Balance in Birds by the Neuroendocrine Hypothalamus
The Journal of Poultry Science, 2005 The physiological regulation of energy homeostasis is critical to an animal’s long-term survival and is relevant to the poultry industry in relation to animal production and welfare. In mammals, rapid progress has been made over the past decade in
Tim Boswell
doaj +1 more source
Role of Zip1 in the regulation of NPY expression by MLT to promote fracture healing in rats
European Journal of Histochemistry, 2020 Our previous study documented that melatonin (MLT) induced the osteogenic differentiation of mesenchymal stem cells (MSCs) and promoted the healing of femoral fractures in rats via the neuropeptide Y (NPY)/neuropeptide Y1 receptor (NPY1R) signaling ...
Junjun Shang +6 more
doaj +1 more source
Advanced Science, EarlyView.A gap‐free genome assembly and multi‐omics comparison of the terrestrial slug Laevichaulis alte with an aquatic relative reveal that expansion of the VEGF family orchestrates mucus production, lipid metabolism, and immune defense—highlighting key molecular innovations for conquering life on land.
Gang Wang +19 more
wiley +1 more source
Origin and Actions of Neuropeptide Y in the Cardiovascular System
The cardiovascular system is richly innervated by sympathetic nerves containing norepinephrine (NE) and neuropeptide Y (NPY). Although NE is considered a major sympathetic neurotransmitter and a primary mediator of cardiovascular functions, the role of ...
Zukowska-Grojec, Zofia +1 more
core +2 more sources
Upregulation of Kiss-1 and Gpr54 Genes Expression in Pituitary of Male Rats Following the Central Administration of Neuropeptide Y [PDF]
International Journal of Basic Science in Medicine, 2019 Introduction: The neuropeptide Y (NPY) in the neural circuits of the hypothalamus has a stimulating effect on reproductive activities in mammals. Kisspeptin (KiSS1) is a quintessential neurotransmitter in the reproductive axis which directly stimulates ...
Vahid Azizi +3 more
doaj +1 more source
Advanced Intelligent Discovery, EarlyView.scTIGER2.0 is a deep‐learning framework that infers gene regulatory networks from single‐cell RNA sequencing data. By integrating correlation, pseudotime ordering, deep learning and bootstrap‐based significance testing, it reduces false positives and reveals directional gene interactions.
Nishi Gupta +3 more
wiley +1 more source
Nitric oxide mediates the neuroproliferative effect of Neuropeptide Y
, 2012 Neuropeptide Y (NPY) is widely expressed in both the central and peripheral nervous system and has an important role in the regulation of adult hippocampal neurogenesis by mediating the proliferation of neural precursor cells in both health and disease ...
Cheung, Angela
core
Animal Research and One Health, EarlyView.Our paper systematically reviews the intestinal structure, function, and microbiota of ostriches, along with strategies for improving their gut health. We analyze how these factors collectively influence intestinal homeostasis and ostrich welfare, emphasizing probiotics as a promising intervention to enhance gut health, boost population well‐being, and
Zi‐Qun Zhang +6 more
wiley +1 more source
Inhibitory Interneurons of The Human Neocortex after Clinical Death
Общая реаниматология, 2016 Objective: to analyze the human neocortex interneurons (areas 4, 10, 17 and 21 by Brodmann) after cardiac arrest (clinical death).Materials and methods.
V. A. Akulinin +4 more
doaj +1 more source