Results 31 to 40 of about 908,208 (245)

The neuroprotective effect of Sulindac after ischemia-reperfusion injury in rats [PDF]

Acta Cirúrgica Brasileira, 2014
PURPOSE: To investigate the neuroprotective effects of Sulindac on the hippocampal complex after global cerebral ischemia/reperfusion (I/R) injury in rats.METHODS: Thirty one Sprague-Dawley rats were used, distributed into group I (sham) n:7 were used as
Murat Cosar, Tuncay Kaner, Onder Sahin, Naci Topaloglu, Mustafa Guven, Adem Bozkurt Aras, Tarık Akman, Adile Ozkan, Halil Murat Sen, Gulsum Memi, Mustafa Deniz   +10 more
doaj   +1 more source

Lung transcriptome sequencing anlysis in Male Sprague-Dawley rats

, 2020
Lung transcriptome sequencing anlysis in LPS-induced ALI model rats (Male Sprague-Dawley rats) after treatment with Ma Xing Shi Gan ...
li, qianqian
core   +1 more source

Bioinspired Hydrogels with Broadly Programmable Mechanics for Soft‐Tissue Interfaces

Advanced Functional Materials, EarlyView.
Sea cucumber‐inspired gelatin hydrogels are formed by directional freezing and mechanically programmed through subsequent ionic treatment. Multiscale characterization and modeling link ion‐regulated chain interactions to directional load transfer within the aligned hierarchical architecture.
Youchao Teng, TzuChun Chung, Katpady Akhil Tantry, Siyu Wu, Jing Tian, Yunqi Cui, Lanyu Li, Yongzan Zhou, Zhilei Zhang, Zhe Su, Gaili Cao, Kun‐Wei Yeh, Ruipeng Li, Xianghui Xiao, Adam F. G. Leontowich, Yuan‐Yu Hsueh, Zhao Pan, Kam C. Tam, Badri Narayanan, Song Li, Yimin. A. Wu   +20 more
wiley   +1 more source

A New Bioactive Glass‐Based Hybrid Bioink With Enhanced Cell Viability and Antibacterial Properties

Advanced Healthcare Materials, EarlyView.
Graphical illustration of the production and characterization process, demonstrating the multiple functions of the new hybrid gelatin methacryloyl‐silver‐bioactive glass (GAB) material. Created in https://BioRender.com. ABSTRACT Recent advances in three‐dimensional bioprinting (3DBP) technology enable the production of customized bone substitutes ...
Adam C. Marsh, Ehsanul Hoque Apu, Theofania Kleisoura, Romila Manchanda, Valerie Johnson, Ginger Ross, Ioannis Tsamesidis, Eleana Kontonasaki, DeMarcus Bunn, Ahmet Erdem, Neal D. Hammer, Kurt D. Hankenson, Christopher H. Contag, Nureddin Ashammakhi, Xanthippi Chatzistavrou   +14 more
wiley   +1 more source

Safety evaluation of CuminUP60® – A novel curcumin complex

Toxicology Reports, 2022
Curcuma longa L. is one of the most recognized Curcuma species (Sharifi-Rad et al., 2020 [3]). Curcumin, the primary polyphenolic compound found in turmeric has been used for a variety of purposes for centuries.
Margitta Dziwenka, Xin Li, Wenyu Li, Jiancheng Zong, Lei Zong, Shanglong Wang, Li Li, Zimin Liu, Zengliang Zhang, Mengyue Wang   +9 more
doaj   +1 more source

Conjugated Porphyrin Polymer With Superior Charge Transfer for Photodynamic‐Immunomodulatory Prevention of CIED Infection in Diabetes

Advanced Healthcare Materials, EarlyView.
Under NIR irradiation, PTCPP generates ROS to eliminate MRSA biofilms and promote M1 macrophage polarization for phagocytosis. After bacterial clearance, the material is phagocytosed by macrophages, shifting their polarization to M2 phenotype via metabolic reprogramming, which synergistically enhances anti‐infection therapy and wound healing.
Honghao Ma, Jinguo Xu, Rongrong Gu, Chuanhui Dong, Te Chen, Yi Mu, Jing Zhu, Yating Wang, Wen Wang, Yingying Zhang, Hongyu Ma, Xiaochen Wang, Sheng Ye, Cheng Cheng   +13 more
wiley   +1 more source

Determination of Biological Activity of Gonadotrophins in Randombred and Sprague Dawley Rats. Part 2. Determination of Biological Activity of Luteinising Hormone

Регуляторные исследования и экспертиза лекарственных средств
INTRODUCTION. The tendency towards reducing the use of laboratory animals in pharmaceutical quality assessment, along with the development of new technologies for gonadotrophin production, necessitate the development of novel assays to determine the ...
T. A. Batuashvili, E. O. Chechetova, P. V. Shadrin, N. P. Neugodova   +3 more
doaj   +1 more source

Targeting CD300a Signaling With a Phosphatidylserine‐Presenting Hydrogel Rescues Macrophage Dysfunction and Accelerates Diabetic Wound Healing

Advanced Healthcare Materials, EarlyView.
Schematic illustration of the proposed mechanism: PEG/RGD‐PSLs mimic apoptotic cells to engage PS receptors (notably CD300a), transducing an inhibitory signal that suppresses the MyD88/NF‐κB pathway, leading to global anti‐inflammatory and pro‐reparative effects.
Lele Wu, Xuetong Hao, Yang Zou, Xinglin Chen, Junyan Kong, Chunning Gu, Wenjie Ma, Zhongjun Yang, Huifen Liu, Mengmeng Liu, Xin Tong   +10 more
wiley   +1 more source

Characterization of Diabetic Neuropathy in the Zucker Diabetic Sprague-Dawley Rat: A New Animal Model for Type 2 Diabetes

Journal of Diabetes Research, 2014
Recently a new rat model for type 2 diabetes the Zucker diabetic Sprague-Dawley (ZDSD/Pco) was created. In this study we sought to characterize the development of diabetic neuropathy in ZDSD rats using age-matched Sprague-Dawley rats as a control.
Eric P. Davidson, Lawrence J. Coppey, Amey Holmes, Sergey Lupachyk, Brian L. Dake, Christine L. Oltman, Richard G. Peterson, Mark A. Yorek   +7 more
doaj   +1 more source

Effect of Injection Botox in Masseter Muscle on Morphometric Measurements of The Mandible in Sprague Dawley Rats

Pakistan Armed Forces Medical Journal, 2022
Objective: To study the effects of injection botox in masseter muscle on the morphometric measurement of underlying mandible and total body weight change in Sprague Dawley rats. Study Design: Laboratory-based experimental study. Place and Duration of
Maria Iram, Muhammad Rizwan Bashir Kiani, Khadija Qamar, Saima Saleem, Muhammad Fahad Atta, Iram Zakria   +5 more
doaj   +1 more source