Results 11 to 20 of about 246,656 (307)
Sex Differences in Intestinal P-Glycoprotein Expression in Wistar versus Sprague Dawley Rats [PDF]
Pharmaceutics, 2022 Wistar and Sprague Dawley are the most common strains of rat used in pharmaceutical research and are used interchangeably in pre-clinical drug development.
Christine M. Madla +8 more
doaj +2 more sources
Sex-specific reference intervals of hematologic and biochemical analytes in Sprague-Dawley rats using the nonparametric rank percentile method. [PDF]
PLoS ONE, 2017 Hematologic and biochemical analytes of Sprague-Dawley rats are commonly used to determine effects that were induced by treatment and to evaluate organ dysfunction in toxicological safety assessments, but reference intervals have not been well ...
Qili He +9 more
doaj +3 more sources
Study on chronic toxicity of rhubarb extract in Sprague-Dawley rats
Heliyon, 2022 Objective: The purpose of this study was to evaluate the safety of rhubarb extract. Methods: SD rats were treated with rhubarb extract at 0, 101, 405 and 1620 mg/kg/day for 52 weeks. food consumption and body weights were recorded.
Wenxiang Yang +7 more
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High dietary salt does not significantly affect plasma 25-hydroxyvitamin D concentrations of Sprague Dawley rats [PDF]
BMC Research Notes, 2010 Background The Dahl salt-sensitive rat, but not the Dahl salt-resistant rat, develops hypertension and hypovitaminosis D when fed a high salt diet. Since the salt-sensitive rat and salt-resistant rat were bred from the Sprague Dawley rat, the aim of this
Bayorh Mohamed A +3 more
doaj +2 more sources
Pharmacokinetic data of synthetic cathinones in female Sprague-Dawley rats
Data in Brief, 2018 The synthetic cathinones methylone, butylone, and pentylone differ from each other through the one carbon lengthening of the α-alkyl chain: methylone (-CH3), butylone (-CH2CH3), and pentylone (-CH2CH2CH3) while 3,4-methylenedioxymethamphetamine (MDMA ...
Gregory G. Grecco +2 more
doaj +2 more sources
Biometric Data Comparison Between Lewis and Sprague Dawley Rats
Frontiers in Veterinary Science, 2019 Introduction: Pressure mapping systems are often used for indirect assessment of kinematic gait parameter differences after repair of critical peripheral nerve defects in small animal models.
Richard Steiner +6 more
doaj +3 more sources
Subacute oral toxicity of ayurvedic anti-diabetic preparation Jambadyarista in Sprague-Dawley rats [PDF]
Toxicology Reports, 2020 Background: Jambadyarista is an Ayurvedic polyherbal formulation widely prescribed by Ayurvedic practitioners for the management of diabetes and its associated complications.
Mahedi Hasan +9 more
doaj +3 more sources
Oman Medical Journal, 2022 Objectives: We sought to investigate the healing efficacy of thermosensitive in situ gelling formulation containing metronidazole and diclofenac potassium on ligature-induced periodontitis (LIP) in rats. Methods: We used 30 adult male Sprague-Dawley rats;
Nida M. A. Wadi +2 more
doaj +1 more source
Hermaphroditism in a Sprague-Dawley Rat [PDF]
Veterinary Pathology, 2007 A spontaneous case of unilateral true hermaphroditism was observed during the routine necropsy of a 9–week-old presumed female Sprague-Dawley rat on a repeat-dose toxicity study. There were no drug-related effects observed. True hermaphroditism is rare in rats, and despite the large numbers of rats examined annually, few cases are reported in the ...
R W, Diters +4 more
openaire +2 more sources
Physiological Reports, 2021 Background Local ischemic preconditioning (IPC) and remote ischemic conditioning (RIC) induced by brief periods of ischemia and reperfusion protect against ischemia‐reperfusion injury.
Thomas Ravn Lassen +6 more
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