Results 31 to 40 of about 1,545,547 (221)

UV Laser‐Induced Carbon Microelectrode Arrays for Neuronal Recordings

Advanced Healthcare Materials, EarlyView.
Thin‐film electrodes are flexible devices of high conformability and minimal dimensions with attractive properties for in vivo and in vitro bioelectronics. Here, electrodes are developed from parylene films via ultraviolet laser‐induced carbonization.
Fulvia Del Duca, Koji Sakai, Beatrice De Chiara, Toichiro Goto, Defne Tüzün, Lukas Hiendlmeier, George Al Boustani, Hu Peng, Tetsuhiko F. Teshima, Simon N. Jacob, Bernhard Wolfrum   +10 more
wiley   +1 more source

Biocompatible PVDF Nanofibers with Embedded Magnetite Nanodiscs Enable Wireless Magnetoelectric Stimulation in Premotor Cortex

Advanced Healthcare Materials, EarlyView.
Flexible, biocompatible PVDF nanofibers embedded with magnetite nanodiscs enable wireless magnetoelectric neuromodulation. Shape anisotropy of the nanodiscs facilitates magnetostrictive strain transfer under alternating magnetic fields, allowing activation of neurons in vitro and behavioral modulation in vivo, without requiring rigid implants or ...
Lorenzo Signorelli, Anouk Wolters, Vicente Durán Toro, Jonas Englhard, Mahdieh Shojaei Baghini, Elif Koçar, Franziska Wasner, Nadine I. Goldenstein, Hadi Heidari, Julien Bachmann, Sarah Hescham, Danijela Gregurec   +11 more
wiley   +1 more source

Advancements in Dissolving Microneedles for Effective Transdermal Delivery in Rheumatoid Arthritis Treatment

Advanced Materials Interfaces, EarlyView.
Rheumatoid arthritis, a chronic inflammatory joint disease, faces limitations with conventional therapies. Dissolving microneedles (DMNs) enable biocompatible, high‐capacity transdermal drug delivery. However, skin elasticity challenges their strength, limiting drug release depth.
Wangrui Peng, MeeiChyn Goh, Jie Lan, Meng Du, Zhiyi Chen   +4 more
wiley   +1 more source

A Hydrophilic Hollow Microneedle Platform for Sampling Interstitial Fluid and On‐Site Biomarker Detection

Advanced Materials Technologies, EarlyView.
This study presents a superhydrophilic 3D‐printed hollow microneedle patch for continuous interstitial fluid (ISF) extraction and on‐patch biomarker sensing. Combining projection micro‐stereolithography and chemical vapor deposition, high‐resolution microneedles with enhanced wettability are fabricated, enabling passive ISF uptake without external ...
Taher Abbasiasl, Sevgi Sarıca, Umut Can Yener, Emel Yilgor, Iskender Yilgor, Hatice Ceylan Koydemir, Ece Öztürk, Levent Beker   +7 more
wiley   +1 more source

Microneedles From Shape‐Preserving Crosslinked Poly(Vinyl Alcohol) Hydrogels: Minimising Interference in Transdermal Proteomics

Advanced Materials Technologies, EarlyView.
Hydrogel‐forming microneedle patches are developed using shape‐preserving PVA‐PVP hydrogels, with and without chitosan, for minimally invasive transdermal protein biomarker sampling. The optimised patches enable efficient interstitial fluid uptake and proteomic analysis, while minimising interference.
Achmad Himawan, Robert Graham, Fabiana Volpe‐Zanutto, Huanhuan Li, Anjali K. Pandya, Andi Nur Aisyah, Rina Agustina, Juan L. Paris, Juan Dominguez‐Robles, Lalitkumar K. Vora, Andi D. Permana, Christopher J. Scott, Ryan F. Donnelly   +12 more
wiley   +1 more source

Parathyroid Gland Carcinoma in a Wistar Rat [PDF]

Veterinary Pathology, 2003
An anaplastic carcinoma was found in one of the two parathyroids of a 2-year-old male Wistar rat, which was sacrificed at the end of a carcinogenicity study. Morphologically, it was characterized by the presence of nodular areas of pleomorphic and dense cells with numerous atypical mitoses and large regions of smaller and dark monomorphic cells devoid
E. Perentes, V. Pace, S. Scarsella
openaire   +3 more sources

When Cellulose Moves: Smart Sensors and Actuators

Advanced Materials Technologies, EarlyView.
This review highlights cellulose‐derived soft actuators alongside with cellulose‐based sensors. Emphasis is placed on their integration into multifunctional devices that couple sensing and actuation to mimic natural motion and adaptability. We also discuss the challenges of achieving robust, reversible, and multi‐stimuli‐responsive motion, and outline ...
Francisco Sousa, José F. Malta, Ana P. C. Almeida   +2 more
wiley   +1 more source

Chronic Psychological Stress Induces Cardiomyocyte Hypertrophy Through Corticosterone‐Glucocorticoid Receptor‐LAMA5 Axis

Advanced Science, EarlyView.
In vivo experiments suggest that cardiomyocyte hypertrophy is an early manifestation of cardiac pathological changes induced by chronic psychological stress. In vivo and in vitro experiments suggest that the corticosterone‐glucocorticoid receptor‐LAMA5 axis mediates cardiomyocyte hypertrophy induced by chronic psychological stress. The clinical results
Chuanjing Zhang, Yongfei Song, Xiaojun Jin, Qingbo Xu, Honghua Ye, Zhuonan Wu, Hui Lin, Jiale Hu, Chen Huang, Jianqing Zhou, Jiangfang Lian   +10 more
wiley   +1 more source

The Establishment of Metabolic Syndrome Model by Induction of Fructose Drinking Water in Male Wistar Rats

BioMed Research International, 2014
Background. Metabolic syndrome can be caused by modification of diet by means of consumption of high carbohydrate and high fat diet such as fructose. Aims.
Norshalizah Mamikutty, Z. C. Thent, S. R. Sapri, N. N. Sahruddin, Mohd Rafizul Mohd Yusof, F. Haji Suhaimi   +5 more
semanticscholar   +1 more source

Deficiency of SCAMP5 Triggers Pancreatic β‐Cell Secretory Dysfunction and Apoptosis

Advanced Science, EarlyView.
This study demonstrates that hyperglycemia in diabetes activates ChREBP, which epigenetically represses SCAMP5 expression in pancreatic β‐cells. This SCAMP5 deficiency impairs insulin secretion by downregulating the calcium channel CaV1.2. Furthermore, reduced SCAMP5 triggers β‐cell apoptosis by stabilizing VDAC1 and enhancing its interaction with Bax,
Yingqi Zhang, Donglan Tang, Chenxi Yang, Chao Lin, Yingyue Yuan, Meiying He, Yiying Chen, Zhuo Mao, Ying Ying, Xiaosong Ma, Xiangchen Kong   +10 more
wiley   +1 more source