Results 41 to 50 of about 1,545,547 (221)
Background: The conflicting roles of quercetin against tissue pathologies associated with oxidative stress are known. Objective: To evaluate the effect of quercetin at doses of 5 mg/kg (Q5) or 10 mg/kg (Q10) against atrazine (120 mg/kg, ATZ)-induced ...
S. Abarikwu
semanticscholar +1 more source
Pulmonary fibrosis (PF) is promoted by NETs that induce fibroblast activation. PEG‐PIm, a polymeric artificial DNase is reported that efficiently degrades NET‐DNA via phosphodiester bond hydrolysis. Inhalation of PEG‐PIm in a mouse PF model prevents fibroblast activation and fibrosis progression, offering a promising therapeutic strategy for NET ...
Yibo Du+7 more
wiley +1 more source
Biochemical Evaluation of Silver Nanoparticles in Wistar Rats
Background. Silver nanoparticles have found wider and increasing biomedical applications due to their broad antimicrobial characteristics. However, toxicity of nanoparticles is a subject of continued controversy, thus necessitating further studies in ...
O. Adeyemi, I. Adewumi
semanticscholar +1 more source
Shear‐activated nanoparticles carrying nitroglycerin selectively target high‐shear stress collateral vessels during ischaemic stroke, enhancing blood flow to at‐risk brain without systemic side effects. This novel approach significantly improves outcomes in animal models, outperforming conventional nitroglycerin delivery.
Magdalena Litman+21 more
wiley +1 more source
An injectable, photocrosslinkable hydrogel sealant—comprising GelMAG, DMA, and pDDA—demonstrated strong underwater adhesion, elasticity, biocompatibility, and broad‐spectrum antibacterial activity. This material rapidly sealed dynamic internal organ injuries and significantly reduced blood loss in vivo. Its superior performance over commercial products
Saumya Jain+6 more
wiley +1 more source
Wistar rats: a forgotten model of age-related hearing loss
Age-related hearing loss (ARHL) is one of the most frequent sensory impairments in senescence and is a source of important socio-economic consequences.
J. Alvarado+4 more
semanticscholar +1 more source
Influence of nifedipine on gingiva of Wistar rats
Noninflammatory hyperplastic growth of gingiva induced by calcium channel blockers, mostly nifedipine, is often seen in everyday dental practice. In order to establish an association of nifedipine and gingival hyperplasia, experimental model was used. Wistar rats were given water solution of nifedipine in different daily doses, using specially designed
openaire +4 more sources
Atrial Fibroblasts‐Derived Extracellular Vesicles Exacerbate Atrial Arrhythmogenesis
Exosome miR‐224‐5p derived from angiotensin II‐treated atrial fibroblasts creates a substrate for AF by promoting atrial electrical remodeling. Increased exosome miR‐224‐5p enhances AF susceptibility by inhibiting CACNA1c expression and decreasing ICa current of atrial cardiomyocytes.
Yue Yuan+13 more
wiley +1 more source
This work found that early‐stage insulin sensitization but late‐stage insulin resistance in prenatal caffeine exposure (PCE)‐ induced intrauterine growth restriction (IUGR) offspring may be related to the hepatic AGEs accumulation via intrauterine GR/miR‐1224 programming by glucocorticoids.
Yongguo Dai+5 more
wiley +1 more source
Cydonia oblonga Miller (quince) is regarded as a potent libido invigorator in Tib-e-Nabvi and Unani System of Medicine. This study was carried out to evaluate the aphrodisiac activity of the hydroalcoholic extract of the fruits of Cydonia oblonga Miller (
M. Aslam, Ali Akbar Sial
semanticscholar +1 more source