Results 11 to 20 of about 3,038,279 (306)

Effect of ovariectomy on the progression of chronic kidney disease-mineral bone disorder (CKD-MBD) in female Cy/+ rats [PDF]

, 2019
Male Cy/+ rats have shown a relatively consistent pattern of progressive kidney disease development that displays multiple key features of late stage chronic kidney disease-mineral bone disorder (CKD-MBD), specifically the development of cortical bone ...
Allen, Matthew R., Chen, Neal X., Hill Gallant, Kathleen M., Lachcik, Pamela J., Metzger, Corinne E., Moe, Sharon M., Swallow, Elizabeth A., Vorland, Colby J.   +7 more
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Bazedoxifene, a selective estrogen receptor modulator, reduces cerebral aneurysm rupture in Ovariectomized rats. [PDF]

, 2017
BackgroundEstrogen deficiency is thought to be responsible for the higher frequency of aneurysmal subarachnoid hemorrhage in post- than premenopausal women.
Hashimoto, Tomoki, Kitazato, Keiko T, Korai, Masaaki, Maekawa, Hidetsugu, Miyamoto, Takeshi, Nagahiro, Shinji, Satomi, Junichiro, Tada, Yoshiteru, Yagi, Kenji   +8 more
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Burning the Rat [PDF]

Emerging Infectious Diseases, 2007
I find him lying by the door, legs outstretched as if he died in mid-leap. I pick him up by the tail. He feels loose, beyond the first stiffness of death. His molecules have realized the futility of hanging on; they know the party's over, it's time to head home. Suddenly, I want to burn this rat. I surprise myself at how much I want this.
openaire   +3 more sources

Wellbeing of Alcohol-preferring Rats Euthanized with Carbon Dioxide at Very Low and Low Volume Displacement Rates [PDF]

, 2019
The 2013 AVMA Guidelines on Euthanasia recommend the use of very-low or low flow rates of 100% carbon dioxide to euthanize small rodents. Although inhalation of high concentrations of carbon dioxide are generally recognized as painful in humans, whether ...
Hickman, Debra L.
core   +1 more source

Dysfunctional play and dopamine physiology in the Fischer 344 rat

, 2011
Juvenile Fischer 344 rats are known to be less playful than other inbred strains, although the neurobiological substrate(s) responsible for this phenotype is uncertain.
Akopian, Akopian, Akopian, Alcaro, Alessandri, Almeida, Baldwin, Bamford, Basar, Beatty, Beatty, Bell, Berridge, Breier, Broderick, Burgdorf, Burgdorf, Burghardt, Burghardt, Burghardt, Cadoni, Cadoni, Calabresi, Chambers, Cheng, Cordier, Crawford, Crawley, Cynthia A. Crawford, Davis, Depoortere, Fagen, Feifel, Field, Fleckenstein, Gainetdinov, Garnik Akopian, Garris, Geyer, Glowa, Gomez-Serrano, Gonon, Gordon, Guitart, Gulley, Guo, Gurden, Hariri, Harris, Helmeste, Huang, Huang, Hubbard, Humphries, Ikemoto, John P. Walsh, Kerr, Knutson, Kolomiets, Kosten, Leblois, Leipold, McGraw La, Meaney, Miles, Niesink, Panksepp, Panksepp, Panksepp, Panksepp, Panksepp, Patel, Patel, Pellegrini, Pellis, Pellis, Pellis, Pellis, Pellis, Pellis, Pellis, Pellis, Pellis, Petzinger, Pliszka, Reif, Robinson, Romeo, Sagvolden, Schulte, Sills, Siviy, Siviy, Siviy, Siviy, Siviy, Siviy, Skuse, Smith, Smith, Spear, Spinka, Stamford, Stephen M. Siviy, Stohr, Sulzer, Surmeier, Swerdlow, Swerdlow, Swerdlow, Tang, Terranova, Trezza, Trezza, Trezza, Trezza, Tripp, Van den Berg, Vanderschuren, Vanderschuren, Vanderschuren, Varty, Villar, Volkow, Voorn, Walker, Young   +126 more
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Direct and long-lasting effects elicited by repeated drug administration on 50-kHz ultrasonic vocalizations are regulated differently: Implications for the study of the affective properties of drugs of abuse [PDF]

, 2013
Several studies suggest that 50-kHz ultrasonic vocalizations (USVs) may indicate a positive affective state in rats, and these vocalizations are increasingly being used to investigate the properties of psychoactive drugs.
FRAU L, MORELLI M, PLUMITALLO A, SIMOLA N   +3 more
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Adrenarche in the rat [PDF]

Journal of Endocrinology, 2006
Normal pubertal development in humans involves two distinct processes: maturation of adrenal androgen secretion (adrenarche) and activation of the hypothalamic–pituitary–gonadal axis (gonadarche). One factor thought to contribute to the adrenarche in man is increased adrenal 17-hydroxylase (CYP17) activity.
Duarte Pignatelli, Gavin P. Vinson, Fang Xiao, Alexandra Gouveia, Jorge G Ferreira   +4 more
openaire   +2 more sources

Effects of Amphetamine on Striatal Dopamine Release, Open-Field Activity, and Play in Fischer 344 and Sprague–Dawley Rats

, 2015
Previous work from our laboratories has shown that juvenile Fischer 344 (F344) rats are less playful than other strains and also appear to be compromised in dopamine (DA) functioning.
Akopian, Garnik, Eck, Samantha R., McDowell, Lana S., Siviy, Stephen M., Turano, Alexandra, Walsh, John P.   +5 more
core   +1 more source

Pulmonary effects of inhalation of spark-generated silver nanoparticles in Brown-Norway and Sprague-Dawley rats [PDF]

, 2016
The increasing use of silver nanoparticles (AgNPs) in consumer products is concerning. We examined the potential toxic effects when inhaled in Brown-Norway (BN) rats with a pre-inflammatory state compared to Sprague-Dawley (SD) rats.We determined the ...
Buckley, A, Chung, KF, Dai, R, Gong, J, Gow, A, Guo, C, Hodgson, A, Hussain, F, Leo, B, Martin, NG, Porter, A, Ryan, M, Seiffert, J, Smith, R, Tetley, T, Warren, J, Zhang, J, Zhu, J   +17 more
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Abnormal hippocampal melatoninergic system: a potential link between absence epilepsy and depression-like behavior in WAG/Rij rats? [PDF]

, 2018
Absence epilepsy and depression are comorbid disorders, but the molecular link between the two disorders is unknown. Here, we examined the role of the melatoninergic system in the pathophysiology of spike and wave discharges (SWDs) and depression-like ...
Battaglia, Giuseppe, Bucci, Domenico, Celli, Roberta, De Fusco, Antonio, Mastroiacovo, Federica, Moyanova, Slavianka, Nicoletti, Ferdinando, Santolini, Ines, Tchekalarova, Jane   +8 more
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