Results 201 to 210 of about 1,985,228 (317)

Genetic attenuation of ALDH1A1 increases metastatic potential and aggressiveness in colorectal cancer

Molecular Oncology, EarlyView.
Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova, Zuzana Kozovska, Ondrej Pos, Kristina Pavlov, Sachin Gulati, Peter Makovicky, Kristina Jakic, Monika Burikova, Eva Sedlackova, Barbora Svitkova, Silvia Tyciakova, Vojtech Bystry, Nicolas Blavet, Boris Tichy, Matej Hrnciar, Jaroslav Budis, Miroslav Tomas, Peter Dubovan, Georgina Kolnikova, Veronika Repaska, Nikoleta Mojzesova, Eva Zomborska, Daniel Pindak, Michal Mego, Tomas Szemes, Miroslava Matuskova   +25 more
wiley   +1 more source

Correction to "Sang-qi Granula Reduces Blood Pressure and Myocardial Fibrosis by Suppressing Inflammatory Responses Associated with the Peroxisome Proliferator-Activated Receptors and Nuclear Factor κB Protein in Spontaneously Hypertensive Rats". [PDF]

Evid Based Complement Alternat Med
europepmc   +1 more source

Norisoboldine Induces Endothelium-Dependent Vasorelaxation and Attenuates Hypertension by Modulating Ca²⁺-eNOS Signaling, Oxidative Stress, and Inflammation. [PDF]

Antioxidants (Basel)
Li J, Wang S, Jin E, Zhao Z, Liang J, Lee YJ, Cao L.   +6 more
europepmc   +1 more source

Ratlarda; düşük, orta ve yüksek derecede gürültünün stres parametreleri ve sperm kalitesindeki değişiklikler üzerine etkisi / Effect of low, medium and high degree noise on stress parameters and changes in sperm quality in rats

, 2017
Osman Sedat Tanyeri
openalex   +1 more source

Targeted modulation of IGFL2‐AS1 reveals its translational potential in cervical adenocarcinoma

Molecular Oncology, EarlyView.
Cervical adenocarcinoma patients face worse outcomes than squamous cell carcinoma counterparts despite similar treatment. The identification of IGFL2‐AS1's differential expression provides a molecular basis for distinguishing these histotypes, paving the way for personalized therapies and improved survival in vulnerable populations globally.
Ricardo Cesar Cintra, Lucca Paolo Hsu Helmich, Daniel Rodrigues de Bastos, Laura Sichero, Patrícia Savio de Araujo‐Souza, Fabio Passetti, Luisa Lina Villa   +6 more
wiley   +1 more source

<p>Echinacoside alleviates asthenozoospermia by upregulating Sox5‑mediated transcriptional activation of the CatSper gene</p>. [PDF]

Mol Med Rep
Jin ZR, Huo YW, Liu BH, Tian H, Yuan S, Tian Y, Xi K, Cai J, Jiang H, Jiang Y, Xing GG.   +10 more
europepmc   +1 more source

Rethinking plastic waste: innovations in enzymatic breakdown of oil‐based polyesters and bioplastics

FEBS Open Bio, EarlyView.
Plastic pollution remains a critical environmental challenge, and current mechanical and chemical recycling methods are insufficient to achieve a fully circular economy. This review highlights recent breakthroughs in the enzymatic depolymerization of both oil‐derived polyesters and bioplastics, including high‐throughput protein engineering, de novo ...
Elena Rosini, Nicolò Antonelli, Gianluca Molla   +2 more
wiley   +1 more source

Inhibitory effects of water chestnut (<i>Trapa bispinosa</i> Roxb.) extract plus lutein on the progression of cataract and their impact on the retina and aorta in diabetic rats. [PDF]

J Diabetes Metab Disord
Mizuno H, Ishigooka G, Jin D, Takai S, Kida T.   +4 more
europepmc   +1 more source

Effects of Camellia sinensis (L.) Kuntze infusion on cardiac and renal morphophysiological parameters of Wistar rats with type 1 diabetes

, 2021
Luiz Carlos Maia Ladeira
openalex   +1 more source