Results 201 to 210 of about 4,021,770 (291)

Possible role of human ribonuclease dicer in the regulation of R loops

FEBS Open Bio, EarlyView.
R loops play an important role in regulating key cellular processes such as replication, transcription, centromere stabilization, or control of telomere length. However, the unscheduled accumulation of R loops can cause many diseases, including cancer, and neurodegenerative or inflammatory disorders. Interestingly, accumulating data indicate a possible
Klaudia Wojcik, Paulina Krzeminska, Anna Kurzynska‐Kokorniak   +2 more
wiley   +1 more source

Chronic ethanol exposure produces sex-dependent impairments in value computations in the striatum. [PDF]

Sci Adv
Cheng Y, Magnard R, Langdon AJ, Lee D, Janak PH.   +4 more
europepmc   +1 more source

A Study of Rats on a Normal Diet Irradiated daily by the Mercury Vapour Quartz Lamp or kept in Darkness [PDF]

, 1923
Harry Goldblatt, Katharine Marjorie Soames   +1 more
openalex   +1 more source

Soman induces endoplasmic reticulum stress and apoptosis of cerebral organoids via the GRP78‐ATF6‐CHOP signaling pathway

FEBS Open Bio, EarlyView.
Cerebral organoids were employed as a novel model to explore the neurotoxicity of soman. Soman inhibited acetylcholinesterase activity, increased cell apoptosis and upregulated endoplasmic reticulum (ER) stress markers glucose‐regulated protein 78 (GRP78), activating transcription factor 6 (ATF6) and C/EBP homologous protein (CHOP).
Yue Wei, Zhanbiao Liu, Jingjing Shi, Qian Jin, Wenqian Chen, Xuejun Chen, Liqin Li, Hui Chen   +7 more
wiley   +1 more source

Cognitive impairment following maternal separation in rats mediated by the NAD⁺/SIRT3 axis via modulation of hippocampal synaptic plasticity. [PDF]

Transl Psychiatry
Hao K, Chen F, Xu S, Xiong Y, Xu R, Huang H, Shu C, Lv Y, Wang G, Wang H.   +9 more
europepmc   +1 more source

THE EFFECT OF POTASSIUM IN NEPHRECTOMIZED RATS WITH HYPOKALEMIC ALKALOSIS [PDF]

, 1953
Jack Orloff, Thomas J. Kennedy, Robert W. Berliner   +2 more
openalex   +1 more source

Transcutaneous occipital nerve stimulation alleviated migraine related pain by regulating synaptic plasticity and CGRP expression in the periaqueductal gray of male rats. [PDF]

J Headache Pain
Liu Y, Guo S, Li Y, Mao J, Lin X, Liu R, Zhao D, Dong Z, Yu S, Han X.   +9 more
europepmc   +1 more source

The Growth of Rats upon Diets of Isolated Food Substances [PDF]

, 1916
Thomas B. Osborne, Lafayette B. Mendel
openalex   +1 more source

Understanding and Overcoming Immunotherapy Resistance in Skin Cancer: Mechanisms and Strategies

Aging and Cancer, EarlyView.
This narrative review explores the mechanisms driving immunotherapy resistance in skin cancer, including tumor microenvironment factors, genetic mutations, and immune evasion strategies. It highlights potential strategies to overcome resistance, offering insights for improving therapeutic outcomes and guiding future research in personalized ...
Shreya Singh Beniwal, Abhimanyu Chiraparambil Radhakrishnan, Ayanchetty Haripraba, Saif Syed, Gajawada Pragna, Ayush Dwivedi, Akash Rawat, Daniela Castro Calderón, Martin Cevallos‐Cueva   +8 more
wiley   +1 more source

Sex-dependent metabolic and behavioural alterations in a rat model of forced exertion-induced myopathy. [PDF]

BMC Vet Res
Lubbe C, Harvey BH, Viljoen FP, Meyer L, Wolmarans W.   +4 more
europepmc   +1 more source