Influence of ApoE genotype on doxorubicin-induced cognitive impairment in juvenile rats. [PDF]
Patel C, Diglio F, Durham BH, Cole PD.
europepmc +1 more source
Effects of Brown Rice and White Rice on Expression of Xenobiotic Metabolism Genes in Type 2 Diabetic Rats [PDF]
Mustapha Umar Imam, Maznah Ismail
openalex +1 more source
Monitoring circulating tumor DNA (ctDNA) in patients with operable breast cancer can reveal disease relapse earlier than radiology in a subset of patients. The failure to detect ctDNA in some patients with recurrent disease suggests that ctDNA could serve as a supplement to other monitoring approaches.
Kristin Løge Aanestad +35 more
wiley +1 more source
Beneficial Effects of <i>Clitoria ternatea</i> Flower and <i>Citrus limon</i> Fruit Beverage on Nutritional Status, Lipid Profile, and Adipokine Parameters on Male Rats With Obesity. [PDF]
Utami F, Indarto D, Listyawati S.
europepmc +1 more source
Inhibition of Baroreflex Vagal Bradycardia by Selective Stimulation of Arterial Chemoreceptors in Rats [PDF]
Tomohiro Murata +3 more
openalex +1 more source
ATF4‐mediated stress response as a therapeutic vulnerability in chordoma
We screened 5 chordoma cell lines against 100+ inhibitors of epigenetic and metabolic pathways and kinases and identified halofuginone, a tRNA synthetase inhibitor. Mechanistically halofuginone induces an integrated stress response, with eIF2alpha phosphorylation, activation of ATF4 and its target genes CHOP, ASNS, INHBE leading to cell death ...
Lucia Cottone +11 more
wiley +1 more source
Marmelosin Protects Against Metabolic Disturbances in High-Fat Diet and Streptozotocin-Induced Diabetes. [PDF]
Alenezi SK +6 more
europepmc +1 more source
A subset of MMR‐proficient colon cancers responds to neoadjuvant immunotherapy
Tan et al. reveal that a distinct subset of early‐stage pMMR colon cancers can respond to neoadjuvant immunotherapy. In the NICHE‐2 trial, responders (26%) were characterized by chromosomal instability, TP53 mutations, and proliferative cell‐cycle programs, whereas nonresponders showed metabolic and stromal reprogramming with TGF‐β‐driven ...
Eleonora Piumatti +3 more
wiley +1 more source

