Results 21 to 30 of about 4,867,122 (355)

Bone turnover markers in medicamentous and physiological hyperprolactinemia in female rats [PDF]

open access: yesVojnosanitetski Pregled, 2014
Background/Aim. There is a lack of data on the effects of prolactin on calcium metabolism and bone turnover in hyperprolactinemia of various origins.
Radojković Danijela   +2 more
doaj   +1 more source

Streptozotocin‐Induced Diabetic Models in Mice and Rats

open access: yesCurrent Protocols in Pharmacology, 2015
Streptozotocin (STZ) is an antibiotic that produces pancreatic islet β‐cell destruction and is widely used experimentally to produce a model of type 1 diabetes mellitus (T1DM).
B. Furman
semanticscholar   +1 more source

Improved timed-mating, non-invasive method using fewer unproven female rats with pregnancy validation via early body mass increases [PDF]

open access: yes, 2018
For studies requiring accurate conception-timing, reliable, efficient methods of detecting oestrus reduce time and costs, whilst improving welfare. Standard methods use vaginal cytology to stage cycle, and breeders are paired–up using approximately five ...
Agata K Stramek   +18 more
core   +1 more source

The DREADD agonist clozapine N-oxide (CNO) is reverse-metabolized to clozapine and produces clozapine-like interoceptive stimulus effects in rats and mice

open access: yesScientific Reports, 2018
Clozapine-N-oxide (CNO) has long been the ligand of choice for selectively activating Designer Receptors Exclusively Activated by Designer Drugs (DREADDs).
D. F. Manvich   +6 more
semanticscholar   +1 more source

Glutamatergic transmission in the central nucleus of the amygdala is selectively altered in Marchigian Sardinian alcohol-preferring rats: Alcohol and CRF effects [PDF]

open access: yes, 2015
The CRF system of the central nucleus of the amygdala (CeA) is important for the processing of anxiety, stress, and effects of acute and chronic ethanol.
CICCOCIOPPO, Roberto   +7 more
core   +1 more source

Structural trace of adaptation in motive nuclei of spinal cord of rats in hypokinesia and after physical loading in the recovery period

open access: yesRegulatory Mechanisms in Biosystems, 2015
The purpose of this paper is to study the morphological changes of neurocytes in spinal cord of rats in hypokinesia and subsequent physical loading. Studies were performed on 55 laboratory rats of Wistar line.
S. L. Popel   +3 more
doaj   +1 more source

Estrogen Rapidly Enhances Incisional Pain of Ovariectomized Rats Primarily through the G Protein-Coupled Estrogen Receptor

open access: yesInternational Journal of Molecular Sciences, 2014
It has become increasingly apparent that the pain threshold of females and males varies in an estrogen dependent manner. To investigate the modulation of pain by estrogen and the molecular mechanisms involved in this process.
Guanghui An   +3 more
semanticscholar   +1 more source

Infectivity, persistence and serological response of nine Trichinella genotypes in rats

open access: yesParasite, 2001
Domestic and sylvatic Trichinella genotypes were evaluated for infectivity, muscle larvae persistence, and host antibody responses in rats. Groups of rats were inoculated with T. spiralis, T. nativa, T. britovi, three genotypes of T. pseudospiralis (from
Malakauskas A., Kapel C.M.O., Webster P.
doaj   +1 more source

Anxiolytic and antidepressant effect of zinc on rats and its impact on general behavioural parameters [PDF]

open access: yesVojnosanitetski Pregled, 2013
Background/Aim. Zinc is an essential element which has considerable interaction with gamma-aminobutyric acid A type receptors (GABAA) and glutamate receptors in the central nervous system (CNS).
Samardžić Janko   +8 more
doaj   +1 more source

The antiinflammatory and electrophysiological effects of fingolimod on penicillin-induced rats

open access: yesArquivos de Neuro-Psiquiatria, 2022
Background The fact that inflammation triggers epileptic seizures brings to mind the antiepileptic properties of anti-inflammatory drugs. Objective To investigate the electrophysiological and anti-inflammatory effects of fingolimod on an ...
Canan Akünal Türel   +4 more
doaj   +1 more source

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