Results 71 to 80 of about 1,985,228 (317)

The Maximum-Tolerated Dose and Pharmacokinetics of a Novel Chemically Modified Curcumin in Rats

, 2022
Heta Dinesh Bhatt, Steve A McClain, Hsi-Ming Lee, Thomas Zimmerman, Jie Deng, Francis Johnson, Ying Gu, Lorne M Golub   +7 more
openalex   +2 more sources

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

FEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho, Shin Morioka, Junko Sasaki, Takehiko Sasaki   +3 more
wiley   +1 more source

Influence of diabetes on the character of changes of resorption and repair processes in the parodontium and mandibular tissues after tooth extraction

Patologìâ
Today, diabetes mellitus (DM) represents a problem on which the attention of endocrinologists, general practitioners, and dentists is focused. Early pathological changes, which manifest themselves in the oral cavity, determine the relevance and social ...
A. V. Abramov, K. S. Hanchev
doaj   +1 more source

Liquid Hydroxyurea (Xromi) for Children With Sickle Cell Anemia: A New Solution Compounding Existing Problems

Pediatric Blood &Cancer, EarlyView.
Alexandra Power‐Hays, Charles T. Quinn
wiley   +1 more source

By dawn or dusk—how circadian timing rewrites bacterial infection outcomes

FEBS Letters, EarlyView.
The circadian clock shapes immune function, yet its influence on infection outcomes is only beginning to be understood. This review highlights how circadian timing alters host responses to the bacterial pathogens Salmonella enterica, Listeria monocytogenes, and Streptococcus pneumoniae revealing that the effectiveness of immune defense depends not only
Devons Mo, Catherine S. Palmer, Jacqueline M. Kimmey   +2 more
wiley   +1 more source

Genistein affects the morphology of pituitary ACTH cells and decreases circulating levels of ACTH and corticosterone in middle-aged male rats

Biological Research, 2009
The soybean phytoestrogen, genistein, is increasingly consumed as an alternative therapeutic for age-related diseases, namely cardiovascular conditions, cancer and osteoporosis.
VLADIMIR Z AJDŽANOVI, BRANKA T ŠOŠI-JURJEVI, BRANKO R FILIPÓVI, SVETLANA L TRIFUNOVI, DEJAN D BRKIC, MILKA I SEKULI, VERICA LJ MILOSEVI   +6 more
doaj  

Disturbance of nitric oxide synthase constitutive isoforms expression as a pathogenetic factor of complications development after tooth extraction in experimental diabetes mellitus

Patologìâ, 2018
The role of constitutive NOS isoforms (endothelial and neuronal) in pathogenesis of complications development and repair processes disturbances in periodontium after tooth extraction in experimental diabetes mellitus is not studied completely. The aim
K. S. Hanchev, A. V. Abramov
doaj   +1 more source

Hematopoietic (stem) cells—The elixir of life?

FEBS Letters, EarlyView.
The aging of HSCs (hematopoietic stem cells) and the blood system leads to the decline of other organs. Rejuvenating aged HSCs improves the function of the blood system, slowing the aging of the heart, kidney, brain, and liver, and the occurrence of age‐related diseases.
Emilie L. Cerezo, Jonah Anderson, Emilie Dinh Vedrenne, Noël Yeh Martín, Jette Lengefeld   +4 more
wiley   +1 more source

The effect of eight weeks of intense interval training combined with bee pollen consumption on the levels of serotonin, dopamine, and PGC-1α proteins in the hippocampus of rats exposed to cadmium [PDF]

Majallah-i Dānishgāh-i ’Ulūm-i Pizishkī-i Īlām
Introduction:  Neurotransmitters and PGC1α enhance neurological disorders, regulate mitochondrial function, and oxidative stress in the central nervous system, while toxic cadmium damages nervous system structures.
Aref Heydari, Vahid Valipour Dehnou, Firuz Sharafi Deharham, Mehdi Roozbahani   +3 more
doaj  

Rat Coronavirus Infection, Lung, Rat [PDF]

, 1985
Naturally infected adult rats rarely have grossly observable changes. Experimentally infected 9–10 week old axenic rats develop gross lesions in the lung on postinoculation days 6 and 7, which consist of randomly dispersed red-brown to gray foci, less than 1 mm in diameter (Bhatt and Jacoby 1977). Although rat coronavirus may cause fatal pneumonia in a
openaire   +2 more sources