Results 231 to 240 of about 653,164 (286)

Valores de referência hematológicos e bioquímicos de ratos (Rattus novergicus linhagem Wistar) provenientes do biotério da Universidade Tiradentes

open access: green, 2014
Cláudio Moreira de Lima   +6 more
openalex   +1 more source

Targeted Nanodelivery of WGX50 and Curcumin via Gold Nanoparticles for Alzheimer's Therapy

open access: yesJournal of Cellular and Molecular Medicine, Volume 30, Issue 3, February 2026.
ABSTRACT Alzheimer's disease (AD) is a progressive neurodegenerative disorder, posing a global health challenge. It affects millions of people, causing cognitive decline and a heavy burden on healthcare systems. Neuroinflammation is a key pathological feature of AD, often associated with the dysregulation of microRNAs such as hsa‐miR‐146a‐5p. WGX50 (N‐[
Madeeha Shahzad Lodhi   +5 more
wiley   +1 more source

Inhibitory GABAergic Neuron Loss due to Oxidative Damage During Ex Vivo Acute Brain Slice Preparation Influences Genesis and Dynamics of Epileptiform Activity

open access: yesJournal of Neurochemistry, Volume 170, Issue 2, February 2026.
Ex vivo brain slice preparation is a popular technique in neuroscience research with many variations in preparation method. We compared two popular variations in brain slice preparation and found that the choice of brain slice preparation technique significantly affects the viability of neuronal preparation.
Felix Chan   +12 more
wiley   +1 more source

AAV‐Driven miR‐146a Promotes Neurite Outgrowth and Axonal Regeneration in Cortical Neurons

open access: yesJournal of Neurochemistry, Volume 170, Issue 2, February 2026.
In the adult central nervous system (CNS), neuronal regeneration after injury is limited, resulting in poor functional recovery. MicroRNAs (miRNAs), a class of small noncoding RNAs that control gene expression, have gained attention as potential therapeutic agents, although their contribution to CNS repair remains insufficiently understood.
V. U. S. Matos   +12 more
wiley   +1 more source

Genotyping Reveals Potential Sources of Human Leptospirosis Outbreaks in Aotearoa New Zealand

open access: yesZoonoses and Public Health, Volume 73, Issue 1, Page 54-64, February 2026.
ABSTRACT Introduction The introduction of PCR testing for leptospirosis in Aotearoa New Zealand has reduced the availability of serotyping data, and current diagnostic PCRs do not routinely genotype Leptospira. This study genotyped Leptospira from PCR‐confirmed human cases between 2016 and 2023 and compared them with genotypes found in animals to ...
Shahista Nisa   +12 more
wiley   +1 more source

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