Results 81 to 90 of about 2,511,664 (300)

YAP1::TFE3 mediates endothelial‐to‐mesenchymal plasticity in epithelioid hemangioendothelioma

Molecular Oncology, EarlyView.
The YAP1::TFE3 fusion protein drives endothelial‐to‐mesenchymal transition (EndMT) plasticity, resulting in the loss of endothelial characteristics and gain of mesenchymal‐like properties, including resistance to anoikis, increased migratory capacity, and loss of contact growth inhibition in endothelial cells.
Ant Murphy, Samuel Hartzler, Paula A. Vargas Carranza, Shyaman Jayasundara, Madison E. Yates, Nimod D. Janson, Bozhi Liu, Annaleigh Benton, Majid Kazemian, Jason A. Hanna   +9 more
wiley   +1 more source

China’s Steel Industry and Its Impact on the United States: Issues for Congress [PDF]

, 2010
[Excerpt] The rise of China’s steel sector, along with other manufacturing industries, presents issues beyond trade law enforcement. China’s quest for industrial raw materials is having considerable effect on global demand and supply, and as a result ...
Tang, Rachel
core   +2 more sources

Emerging role of ARHGAP29 in melanoma cell phenotype switching

Molecular Oncology, EarlyView.
This study gives first insights into the role of ARHGAP29 in malignant melanoma. ARHGAP29 was revealed to be connected to tumor cell plasticity, promoting a mesenchymal‐like, invasive phenotype and driving tumor progression. Further, it modulates cell spreading by influencing RhoA/ROCK signaling and affects SMAD2 activity. Rho GTPase‐activating protein
Beatrice Charlotte Tröster, Melanie Kappelmann‐Fenzl, Anja Katrin Bosserhoff, Nicole Rachinger   +3 more
wiley   +1 more source

THE GERMANIUM EXTRACTION FROM TECHNOGENIC RAW MATERIALS BY MICROBIOLOGICAL METHODS [PDF]

, 2018
The results have practical significance and can be the basis for developing a unified biotechnological method of technogenic waste processing with a purpose of their sterilization and detoxification with simultaneous obtaining ...
Blaida, Iryna, Ivanytsia, Volodymyr, Sliusarenko, Larysa, Vasylieva, Tetiana   +3 more
core  

mockrobiota: a Public Resource for Microbiome Bioinformatics Benchmarking. [PDF]

, 2016
Mock communities are an important tool for validating, optimizing, and comparing bioinformatics methods for microbial community analysis. We present mockrobiota, a public resource for sharing, validating, and documenting mock community data resources ...
Arron Shiffer, Benjamin Wolfe, Corinne F. Maurice, J. Gregory Caporaso, Jai Ram Rideout, Josh D. Neufeld, Nicholas A. Bokulich, Peter J. Turnbaugh, Rachel J. Dutton, Rob Knight, William G. Mercurio   +10 more
core   +3 more sources

Adaptaquin is selectively toxic to glioma stem cells through disruption of iron and cholesterol metabolism

Molecular Oncology, EarlyView.
Adaptaquin selectively kills glioma stem cells while sparing differentiated brain cells. Transcriptomic and proteomic analyses show Adaptaquin disrupts iron and cholesterol homeostasis, with iron chelation amplifying cytotoxicity via cholesterol depletion, mitochondrial dysfunction, and elevated reactive oxygen species.
Adrien M. Vaquié, Davod R. Shah, Eliane E. S. Brechbühl, Michael McNicholas, Zhaoyang Xu, John H. Stockley, Laura Morcom, Diana Gold Diaz, Gemma C. Girdler, Rachel V. Seear, Gabriel Balmus, Rajiv R. Ratan, Harry Bulstrode, James A. Nathan, Manav Pathania, Kevin M. Brindle, David H. Rowitch   +16 more
wiley   +1 more source

Emerging Renewable Polymer Platforms for Biomedical Interfaces, Bioadhesives, and 3D Printing [PDF]

Physics Access
The traditional polymer industry, which depends heavily on fossil resources, faces increasing challenges due to resource depletion, environmental damage, and sustainability issues linked to petroleum-based materials.
Agbogo U Victor, Okafor O Evelyn, Mamman P Godiya, Igogo A Roseline, Ike-Muonso N Martin, Kollere A Shehu   +5 more
doaj   +1 more source

Predictors of response and rational combinations for the novel MCL‐1 inhibitor MIK665 in acute myeloid leukemia

Molecular Oncology, EarlyView.
This study characterizes the responses of primary acute myeloid leukemia (AML) patient samples to the MCL‐1 inhibitor MIK665. The results revealed that monocytic differentiation is associated with MIK665 sensitivity. Conversely, elevated ABCB1 expression is a potential biomarker of resistance to the treatment, which can be overcome by the combination ...
Joseph Saad, Rhiannon Newman, Elmira Khabusheva, Sofia Aakko, Eric Durand, Mahesh Tambe, Heikki Kuusanmäki, Alun Parsons, Juho J. Miettinen, Komal Kumar Javarappa, Ezgi June Olgac, Nemo Ikonen, Mika Kontro, Kimmo Porkka, Heiko Maacke, Janghee Woo, Ensar Halilovic, Caroline A. Heckman   +17 more
wiley   +1 more source

Global trends in raw materials consumption [PDF]

This paper reviews movements in raw materials consumption over the past 30 years. Included in this review are all base metals and steel, and important agricultural raw materials.
Boum-Jong Choe
core  

Application of Co-bioprocessing Techniques (Enzymatic Hydrolysis and Fermantation) for Improving the Nutritional Value of Wheat Bran as Food Functional Ingrediens [PDF]

, 2019
Last time the food industry pays the great attention to questions, connected with changing existing technologies for raising the efficacy of the raw materials complex processing and increasing the output of high-quality products and food ingredients with
Buzhylov, M. (Mykola), Kaprelyants, L. (Leonid), Pozhitkova, L. (Liliia)   +2 more
core   +3 more sources