Results 81 to 90 of about 2,554,736 (300)
Molecular Oncology, EarlyView.Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang +12 more
wiley +1 more source
Information System Design Reminder Inventory Control at PT Nuansa Timur Lestari [PDF]
, 2020 The current information needs in the business world to be very important in determining the progress of a company. A good activity on a single company or technology is also determined by the available information.
Hasibuan, I. Y. (Irfan) +2 more
core
Interrogating the immune landscape of microsatellite stable RAS‐mutated colon cancer
Molecular Oncology, EarlyView.COLOSSUS project RAS‐mutated MSS colon cancer study explored transcriptomics and immune cell density by immunohistochemistry (IHC), Immunoscore (IS), ISIC/TuLIS scores, mutation counts, and detected different prevalences but similar microenvironment composition across immune markers with clinical relevance for future immunotherapy combination ...
Rodrigo Dienstmann +61 more
wiley +1 more source
Emerging Renewable Polymer Platforms for Biomedical Interfaces, Bioadhesives, and 3D Printing [PDF]
Physics AccessThe traditional polymer industry, which depends heavily on fossil resources, faces increasing challenges due to resource depletion, environmental damage, and sustainability issues linked to petroleum-based materials.
Agbogo U Victor +5 more
doaj +1 more source
Global trends in raw materials consumption [PDF]
This paper reviews movements in raw materials consumption over the past 30 years. Included in this review are all base metals and steel, and important agricultural raw materials.
Boum-Jong Choe
core
Application of Co-bioprocessing Techniques (Enzymatic Hydrolysis and Fermantation) for Improving the Nutritional Value of Wheat Bran as Food Functional Ingrediens [PDF]
, 2019 Last time the food industry pays the great attention to questions, connected with changing existing technologies for raising the efficacy of the raw materials complex processing and increasing the output of high-quality products and food ingredients with
Buzhylov, M. (Mykola) +2 more
core +3 more sources
Molecular Oncology, EarlyView.Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla +9 more
wiley +1 more source
Molecular Oncology, EarlyView.Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch +13 more
wiley +1 more source
Lignocarbohydrate raw materials for obtaining biodegradable materials [PDF]
, 2019 The lignin and cellulose contents in wood and plant raw materials have been reseached. The physicomechanical properties of the obtained biodegradable lignocarbohydrate material were studied.Проведены исследования по определению содержания лигнина и ...
Артемов, А. В. +2 more
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Somatic mutational landscape in von Hippel–Lindau familial hemangioblastoma
Molecular Oncology, EarlyView.The causes of central nervous system (CNS) hemangioblastoma in Von Hippel–Lindau (vHL) disease are unclear. We used Whole Exome Sequencing (WES) on familial hemangioblastoma to investigate events that underlie tumor development. Our findings suggest that VHL loss creates a permissive environment for tumor formation, while additional alterations ...
Maja Dembic +5 more
wiley +1 more source