Myeloproliferative Disease: An Unusual Cause of Raynaud’s Phenomenon and Digital Ischaemia
We describe a 59-year-old female who presented with ischaemic digits, preceded by a 6-month history of Raynaud’s phenomenon affecting her fingers and toes.
Celia Beynon, Gwenan Huws, Tom Lawson
doaj +1 more source
Long-term effects of cyclic therapy with iloprost in systemic sclerosis
Objective: To assess the long-term effects of cyclic infusion of iloprost, a derivative of prostacyclin, on Raynaud’s phenomenon- related symptoms and ischemic ulcers in patients with Systemic Sclerosis (SSc).
A. Grottolo +6 more
doaj +1 more source
Diagnostic Implications and Correlates of Plasma Adenosine Deaminase 2 Activity and ADA2 Variants
Objective Deficiency of adenosine deaminase 2 (DADA2) is a monogenic autoinflammatory disease manifested as polyarteritis nodosa, stroke, and bone marrow failure. Leveraging an international cohort of 200 DADA2 cases, we aimed to characterize the diagnostic utility of a plasma ADA2 enzyme activity assay and understand the implications of residual ADA2 ...
Jian Yue +55 more
wiley +1 more source
Erectile dysfunction is frequent in systemic sclerosis and associated with severe disease: a study of the EULAR Scleroderma Trial and Research group [PDF]
Introduction: Erectile dysfunction (ED) is common in men with systemic sclerosis (SSc) but the demographics, risk factors and treatment coverage for ED are not well known.
Abdel Atty Mohamed, Walid A. +24 more
core
Absence of correlation between morphological and biochemical alterations in the microcirculation of patients with systemic sclerosis [PDF]
OBJECTIVE: The cold stimulus-fingertip lacticemy test (CS-FTL) evaluates a microcirculation biochemical component and presents abnormal results in systemic sclerosis (SSc).
Andrade, Luiz Eduardo Coelho +1 more
core +3 more sources
Cold sensitivity test for individuals with non-freezing cold injury: the effect of prior exercise [PDF]
BACKGROUND: One of the chronic symptoms of non-freezing cold injury (NFCI) is cold sensitivity. This study examined the effects of prior exercise on the response to a cold sensitivity test (CST) in NFCI patients with the aim of improving diagnostic ...
Eglin, Clare, Golden, F., Tipton, Mike
core +1 more source
Objectives The aim of this study is to generate hypotheses about unknown drugs associated with the onset or worsening of Raynaud's phenomenon (RP) and to explore their potential pathophysiologic mechanisms through a mixed disproportionality/clustering analysis from the World Health Organization (WHO) pharmacovigilance database.
Alex Hlavaty +4 more
wiley +1 more source
What is the evaluation and treatment strategy for Raynaud's phenomenon? [PDF]
Raynaud's phenomenon is diagnosed by history, which also plays a key role in distinguishing primary from secondary Raynaud's phenomenon (strength of recommendation [SOR]: C, based on expert opinion).
Jamieson, Barbara +2 more
core
Nailfold capillaroscopy in children and adolescents with rheumatic diseases [PDF]
OBJECTIVE: To assess nailfold capillaroscopy in children and adolescents with autoimmune rheumatic diseases (juvenile idiopathic arthritis, systemic lupus erythematosus, juvenile dermatomyositis, scleroderma and mixed connective tissue disease) and ...
Hilário, Maria Odete Esteves +3 more
core +3 more sources
Exploring the feasibility of an exercise programme including aerobic and resistance training in people with limited cutaneous systemic sclerosis. [PDF]
OBJECTIVES: It is suggested that exercise can improve the vascular function and quality of life (QoL) in people with systemic sclerosis (SSc), potentially offering clinical benefits to this population.
Akil, Mohammed +4 more
core +2 more sources

