Results 51 to 60 of about 1,438,405 (173)

Artificial Intelligence in Systemic Sclerosis: Clinical Applications, Challenges, and Future Directions

Arthritis Care &Research, EarlyView.
Systemic sclerosis (SSc) is a rare autoimmune disease defined by immune dysregulation, vasculopathy, and progressive fibrosis of the skin and internal organs. Despite advances in care, major complications such as interstitial lung disease (ILD) and myocardial involvement remain the leading causes of morbidity and mortality.
Cristiana Sieiro Santos, José Miguel Sequí‐Sabater, Diego Benavent   +2 more
wiley   +1 more source

Response to: Comment on “The evaluation of nailfold capillaroscopy pattern in patients with fibromyalgia’’

The Turkish Journal of Gastroenterology, 2021
We deeply thank to Dr. Lambova for her appreciable point of view and comments on our recent article entitled “The Evaluation of Nailfold Capillaroscopy Pattern in Patients With Fibromyalgia”. The results of our study revealed a significantly higher mean
İlke Coşkun Benlidayı, Esra Kayacan Erdoğan, Aylin Sarıyıldız   +2 more
doaj  

Discordance Between Patient and Physician Global Assessments in Early Systemic Sclerosis

Arthritis Care &Research, EarlyView.
Objective This study aims to identify factors associated with patient global assessment (PtGA) and physician global assessment (PhGA) and discordance between them in systemic sclerosis (SSc). Methods Data from adults with early SSc (<5 years) from the Collaborative National Quality and Efficacy Registry were included.
Ellen Romich, Alexis Ogdie, Alisa Stephens Shields, Peter A. Merkel, Shervin Assassi, Elana J. Bernstein, Andreea Bujor, Flavia V. Castelino, Lorinda Chung, Luke B. Evnin, Tracy M. Frech, Jessica K. Gordon, Melissa Griffith, Faye N. Hant, Monica L. Harding, Laura K. Hummers, Dinesh Khanna, Kimberly S. Lakin, Dorota J. Lebiedz‐Odrobina, Yiming Luo, Ashima Makol, Maureen D. Mayes, Zsuzsanna H. McMahan, Jerry Molitor, Duncan F. Moore, Julie Paik, Carrie Richardson, Brian Skaug, Ami A. Shah, Ankoor Shah, Virginia Steen, John M. VanBuren, Elizabeth R. Volkmann, Carleigh Zahn, Nora Sandorfi, for the CONQUER Investigators   +35 more
wiley   +1 more source

The Gut–Heart Axis in Systemic Sclerosis: Evidence From a Large Prospective Early Disease Cohort

Arthritis Care &Research, EarlyView.
Objective Cardiac involvement significantly impacts prognosis in systemic sclerosis (SSc), highlighting the need for early risk stratification. Gastrointestinal (GI) symptoms are common and often manifest early. Emerging data suggest a link between GI and cardiac manifestations, possibly through shared mechanisms like dysautonomia.
Francesca R. Di Ciommo, Ashish P. Balar, Aidan K. Strother, Subhash Kulkarni, Michael Hughes, Brian Skaug, Maureen D. Mayes, Shervin Assassi, Ali Y. Ayla, Zsuzsanna H. McMahan   +9 more
wiley   +1 more source

Distinct Systemic Sclerosis Phenotypes Related to Ethnicity: An Opportunity to Personalize Care?

Arthritis Care &Research, EarlyView.
Objective The objective is to describe and compare demographic, clinical, and serological characteristics of patients with systemic sclerosis (SSc) according to ethnic background. Methods Participants enrolled in the Canadian Scleroderma Research Group cohort who self‐identified to a single ethnicity group were included.
Danick Goulet, Camille Guertin, Maggie Larché, Isabelle Ferdinand, Marie Hudson, May Y. Choi, Mohammed Osman, Janet Pope, Carter Thorne, Murray Baron, Sasha Bernatsky, Sabrina Hoa   +11 more
wiley   +1 more source

Raynaud's phenomenon secondary to erenumab in a patient with chronic migraine

Clinical Case Reports, 2021
Raynaud's phenomenon is a rare side effect of CGRP monoclonal antibodies. These molecular treatments are a relatively new class of drugs for the prevention of migraine. It is likely that we will see this side effect more often in the future.
Agaath Hedina Manickam, Alina Buture, Esther Tomkins, Martin Ruttledge   +3 more
doaj   +1 more source

Readdressing the role of ADRA2A in Raynaud's phenomenon: Methodological concerns and implications. [PDF]

Cell Genom
We read, with excitement, the important and timely paper titled ‘‘Genetic and functional analysis of Raynaud’s syndrome implicates loci in vasculature and immunity’’ that appeared in volume 4, issue 9 of Cell Genomics in September 2024.1 This manuscript ...
Eid AH.
europepmc   +2 more sources

Real‐World Safety and Effectiveness of JAK Inhibitors in Systemic Sclerosis: A Propensity‐Matched Study From the EUSTAR Cohort

Arthritis Care &Research, EarlyView.
Objective JAK inhibitors (JAKi) have shown promising effects in early‐phase studies of systemic sclerosis (SSc). We aimed to assess the safety and explore the effectiveness of JAKi compared to conventional immunosuppressants in SSc. Methods A longitudinal retrospective study of the European Scleroderma Trials and Research Group (EUSTAR) cohort was ...
Stefano Di Donato, Marie‐Elise Truchetet, Marco Minerba, Oliver Distler, Juan José Alegre Sancho, Yolanda Braun‐Moscovici, Christina Bergmann, Petros Sfikakis, Jeska K. de Vries‐Bouwstra, Murray Baron, Silvia Bellando‐Randone, Lorenzo Dagna, Christopher P. Denton, Madelon C. Vonk, Vanessa Smith, Ivan Castellvi, Gabriela Riemekasten, Andra Balanescu, Masataka Kuwana, Maria De Santis, Kamal Solanki, Anastas Batalov, Vahan Mukuchyan, Marco Matucci‐Cerinic, Yannick Allanore, Francesco Del Galdo, Michael Hughes, EUSTAR Collaborators   +27 more
wiley   +1 more source

Surgical Strategies in the Management of Raynaud's Phenomenon: Comparative Analysis of Trends and Effectiveness Incorporating New Clinical Data

Journal of Education, Health and Sport
Introduction and objective Raynaud's phenomenon is a condition of unknown origin and complex pathophysiology, characterized by an excessive sensitivity to vasoconstriction of arteries in the hands, feet, auricles and nose, leading to a characteristic
Aleksandra Cygnarowicz, Mariola Turemka, Negar Hosseinnejad, Karolina Sacher, Aneta Klaudia Wojtas, Krystyna Zabojska, Mikołaj Biskupski, Urszula Korotko, Kinga Witowska, Aneta Mandziuk   +9 more
doaj   +1 more source

Cold agglutinin disease initially regarded as mechanical hemolysis and alcoholism

Journal of Hospital General Medicine, 2023
Cold agglutinin disease (CAD) is a rare condition that typically presents with a combination of extravascular hemolysis, which is caused by immunoglobulin M binding to the RBC membrane, and cold-induced symptoms such as Raynaud’s phenomenon due to ...
Daisuke Nagase, Yosuke Sasaki, Ai Hirota, Hirofumi Irita, Naoki Onda, Kazuhiko Natori, Yoshihisa Urita   +6 more
doaj   +1 more source