Rethinking Strategies for a Pharmaceutical Approach to Pain Related to Connective Tissue-Related Raynaud Phenomenon in the United States. [PDF]
Objective There are no US Food and Drug Administration–approved therapies for Raynaud phenomenon (RP) in the United States. Clinical trials have been challenged by study design. Important advances in RP patient‐reported outcome measures and mechanistic quantification allow RP‐related pain characterization.
Frech TM +4 more
europepmc +2 more sources
Prevalence and Clinical Characteristics of Systemic Sclerosis in Alaska Native and American Indian Peoples in Alaska. [PDF]
Objective Systemic sclerosis (SSc) is known to exhibit significant epidemiologic and clinical variation. This study aimed to describe the clinical and epidemiologic characteristics of SSc in Alaska Native and American Indian (AN/AI) individuals in Alaska.
Mehta VR +5 more
europepmc +2 more sources
Antisynthetase Syndrome with Severe Interstitial Lung Disease in Pregnancy
Antisynthetase syndrome is a rare multisystem autoimmune disorder which clinically manifests with myositis, arthritis, interstitial lung disease, Raynaud phenomenon, and skin hyperkeratosis. Lung involvement represents the most severe form of disease and
Catalina I. Dumitrascu +4 more
doaj +1 more source
Anti–Jo-1–Positive Antisynthetase Syndrome and Myocarditis: An Underrecognized Clinical Presentation
Antisynthetase syndrome is a distinct entity of overlap myositis in adults and is characterized by muscle weakness, arthritis, mechanic's hands, interstitial lung disease, and Raynaud phenomenon.
Rania Al Asmar +4 more
doaj +1 more source
El fenómeno de Raynaud es una respuesta vascular exagerada al frio o al estrés que se manifiesta por cambios de coloración de la piel en diversas localizaciones, característicamente mostrando tres fases distintas que comprenden palidez, cianosis y rubor.
Jairo Alonso Rodríguez-Criollo +1 more
doaj +1 more source
Raynaud Phenomenon of the Nipple: A Clinical Case Report
Objective: In Raynaud's phenomenon of the nipple there is a change in color, accompanied by pain or discomfort during breastfeeding. Case report: A 29-years old female patient, breastfeeding, develops a severe bilateral nipple pain during and after ...
Carolina Quental +3 more
doaj +1 more source
Digital Ulcers as Presentation of Carpal Tunnel Syndrome
Ulcerating and mutilating variant of carpal tunnel syndrome occurs in longstanding cases of untreated disease. Pa- tients present with painless ulcers of the second and third fingers, accompanied with other cutaneous and sensory changes.
T. F. Gomes +4 more
doaj +1 more source
Cumulative Burden of Morbidity Among Testicular Cancer Survivors After Standard Cisplatin-Based Chemotherapy: A Multi-Institutional Study [PDF]
Purpose In this multicenter study, we evaluated the cumulative burden of morbidity (CBM) among > 1,200 testicular cancer survivors and applied factor analysis to determine the co-occurrence of adverse health outcomes (AHOs).
AnnaLynn M. Williams +20 more
core +1 more source
Two-Step Incision for Periarterial Sympathectomy of the Hand
Background Surgical scars on the palmar surface of the hand may lead to functional and also aesthetic and psychological consequences. The objective of this study was to introduce a new incision technique for periarterial sympathectomy of the hand and to
Seung Bae Jeon +3 more
doaj +1 more source
Immune myopathies with perimysial pathology: Clinical and laboratory features [PDF]
ObjectiveImmune myopathies with perimysial pathology (IMPP) have a combination of damage to perimysial connective tissue and muscle fiber necrosis, more prominent near the perimysium.
Bucelli, Robert C, Pestronk, Alan
core +2 more sources

