Results 21 to 30 of about 22,320 (234)

Genetic Susceptibility to Antisynthetase Syndrome Associated With Single-Nucleotide Variants in the IL1B Gene That Lead Variation in IL-1β Serum Levels

Frontiers in Medicine, 2020
The antisynthetase syndrome (ASSD) is an autoimmune disorder characterized by myositis, arthritis, mechanic's hands, fever, Raynaud phenomenon, and interstitial lung disease (ILD).
Marco Antonio Ponce-Gallegos, Espiridión Ramos-Martínez, Adriana García-Carmona, Mayra Mejía, Karol J. Nava-Quiroz, Gloria Pérez-Rubio, Enrique Ambrocio-Ortiz, Montserrat I. González-Pérez, Ivette Buendía-Roldán, Jorge Rojas-Serrano, Ramcés Falfán-Valencia   +10 more
doaj   +1 more source

The impact of Raynaud’s phenomenon on work ability – a longitudinal study

Journal of Occupational Medicine and Toxicology, 2022
Objective To determine if having Raynaud’s phenomenon (RP) affects the work ability, job retainment, or occurrence of sick leave. Methods Surveys on the working-age general population of northern Sweden were conducted in 2015 and 2021, gathering data on ...
Albin Stjernbrandt, Jens Wahlström
doaj   +1 more source

Mining and state-space modeling and verification of sub-networks from large-scale biomolecular networks [PDF]

, 2007
BMC Bioinformatics 2007, 8:324The problem of mining undiscovered public knowledge from biomedical literature was exemplified by Swanson’s pioneering work on Raynaud disease/fish-oil discovery in 1986.
Hu, Xiaohua, Li, Guangren, Yoo, Illhoi, Zhang, Xiaodan, Hu, Xuheng   +4 more
core   +3 more sources

Raynaud’s phenomenon and positive antinuclear antibodies as first manifestation of POEMS syndrome (polyneuropathy, organomegaly, endocrinopathy, monoclonal gammopathy, and skin changes): a case report

BMC Rheumatology, 2022
Background POEMS syndrome is a rare paraneoplastic syndrome caused by plasma cell disorder almost always lambda restricted. Secondary Raynaud’s phenomenon is an overlooked skin manifestation of the disease even though it is present in twenty percent of ...
Fabio Torres-Saavedra, Lina León-Sierra
doaj   +1 more source

Pulmonary vasospasm in systemic sclerosis: noninvasive techniques for detection [PDF]

, 2014
In a subgroup of patients with systemic sclerosis (SSc), vasospasm affecting the pulmonary circulation may contribute to worsening respiratory symptoms, including dyspnea.
Giannarou, S, Hansell, DM, Keir, GJ, MacDonald, P, Nair, A, Oldershaw, P, Wells, AU, Wort, SJ, Yang, G-Z   +8 more
core   +1 more source

Progressive systemic sclerosis in a child

Indian Journal of Dermatology, 2013
Systemic sclerosis is a clinically heterogeneous systemic disease affecting the connective tissues of skin, walls of blood vessels and internal organs like lung, heart and kidneys. Systemic sclerosis is very unusual in pediatric population.
Arun K De, Kallol Das, Archan Sil, Swarnali Joardar   +3 more
doaj   +1 more source

Effect of nintedanib in patients with systemic sclerosis-associated interstitial lung disease and risk factors for rapid progression

RMD Open, 2023
Objective To investigate the rate of decline in forced vital capacity (FVC), and the effect of nintedanib on the rate of decline in FVC, in subjects with systemic sclerosis-associated interstitial lung disease (SSc-ILD) who had risk factors for rapid ...
Toby M Maher, Michael Kreuter, Vanessa Smith, Yannick Allanore, Elizabeth R Volkmann, Dinesh Khanna, Christopher P Denton, Anna-Maria Hoffmann-Vold, Shervin Assassi, Masataka Kuwana, Margarida Alves, Christian Stock, Steven Sambevski   +12 more
doaj   +1 more source

PTP4A1 promotes TGFβ signaling and fibrosis in systemic sclerosis. [PDF]

, 2017
Systemic sclerosis (SSc) is an autoimmune disease characterized by fibrosis of skin and internal organs. Protein tyrosine phosphatases have received little attention in the study of SSc or fibrosis.
Bai, Yunpeng, Boin, Francesco, Bottini, Nunzio, Ceponis, Arnold, Chernitskiy, Vladimir, Cipriani, Paola, Di Benedetto, Paola, Giacomelli, Roberto, Jimenez, Sergio A, Kaestner, Klaus H, Kiosses, William B, Piera-Velazquez, Sonsoles, Sacchetti, Cristiano, Santelli, Eugenio, Stanford, Stephanie M, Zhang, Zhong-Yin   +15 more
core   +2 more sources

The research progress of the diagnosis and treatment of Raynaud phenomenon [PDF]

Yixue xinzhi zazhi
Raynaud phenomenon (RP) is a disease of intermittent vascular hypercontraction of fingers and toes caused by cold or pressure. Its etiology is closely related to genetic and hormonal factors, though the precise mechanisms remain unclear.
YANG Lihuan, XIA Lianheng, XU Yufei, LI Linggen, GAO Jie   +4 more
doaj   +1 more source

Toxin for Treating Raynaud Conditions in Hands (The TORCH Study): A Systematic Review and Meta-analysis

Plastic and Reconstructive Surgery, Global Open
Background:. Raynaud disease of the hands is a complex disorder resulting in inappropriate constriction and/or insufficient dilation in microcirculation.
Ellen Geary, MD, Justin C.R. Wormald, MRCS, PhD, Kevin J. Cronin, MSc, FRCS, Plast, Henk P. Giele, FRACS, MRACMA, Laura Durcan, MD, FRCPI, Oran Kennedy, PhD, Fergal O’Brien, PhD, Roisin T. Dolan, MD, FRCS, Plast   +7 more
doaj   +1 more source