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A review of three decades of use of the cattle brucellosis rough vaccine Brucella abortus RB51: myths and facts [PDF]

open access: yesBMC Veterinary Research, 2023
Cattle brucellosis is a severe zoonosis of worldwide distribution caused by Brucella abortus and B. melitensis. In some countries with appropriate infrastructure, animal tagging and movement control, eradication was possible through efficient diagnosis ...
J. M. Blasco   +4 more
doaj   +2 more sources

Characterization of the adaptive cellular and humoral immune responses to persistent colonization of Brucella abortus strain RB51 in a Jersey cow [PDF]

open access: yesFrontiers in Veterinary Science
Brucella abortus strain RB51 is the commercial cattle vaccine used in the United States (US) and many parts of the world against bovine brucellosis. RB51 was licensed for use in 1996, and it has been shown to be safe and efficacious in cattle, eliciting ...
Paola M. Boggiatto   +6 more
doaj   +2 more sources

Brucella abortus Strain RB51 Administered to Prepubescent Water Buffaloes, from Vaccination to Lactation: Kinetics of Antibody Response and Vaccine Safety [PDF]

open access: yesMicroorganisms, 2023
Brucella RB51 is a live modified vaccine. Its use in water buffalo has been proposed using a vaccination protocol different to that used for cattle, but knowledge of the long-term effects of RB51 vaccination in this species remains incomplete. The aim of
Fabrizio De Massis   +20 more
doaj   +2 more sources

Effect of co-vaccination of cattle with RB51 and BCG on vaccine-specific CD4+ T cell responses [PDF]

open access: yesFrontiers in Immunology
IntroductionBrucella abortus and Mycobacterium bovis, the causative agents of bovine brucellosis and tuberculosis respectively, are zoonotic bacterial pathogens that both contribute to major economic losses in the cattle industry and pose a human health ...
Haley M. Sterle   +5 more
doaj   +2 more sources

Effects of concurrent administration of modified live viral vaccines with RB51 on immune responses to RB51 [PDF]

open access: yesFrontiers in Veterinary Science, 2023
Brucella abortus is a gram negative, zoonotic pathogen that can cause abortions and stillbirths in the cattle industry and has contributed to significant economic losses to cow-calf producers. Cell mediated immunity (CMI) is an important component of the
Lauren Crawford   +6 more
doaj   +2 more sources

Genome Report—A Genome Sequence Analysis of the RB51 Strain ofBrucella abortusin the Context of Its Vaccine Properties

open access: yesG3: Genes, Genomes, Genetics, 2020
The RB51 vaccine strain of Brucella abortus, which confers safe and effective protection of cattle from B. abortus infection, was originally generated via serial passage of B. abortus 2308 to generate spontaneous, attenuating mutations.
Steven Olsen   +2 more
exaly   +3 more sources

Evaluation of the immunization of camels with Brucella abortus vaccine (RB51) in Egypt [PDF]

open access: yesOpen Veterinary Journal
Background: Brucellosis is a highly contagious zoonotic disease caused by an intracellular facultative microorganism termed Brucella spp. Control of brucellosis depends on test and slaughter policy as well as vaccination programs.
Mousa E. Ahmed   +5 more
doaj   +2 more sources

Comparison of diagnostic tests for detecting bovine brucellosis in animals vaccinated with S19 and RB51 strain vaccines [PDF]

open access: yesVeterinary World, 2023
Background and Aim: The diagnosis of bovine brucellosis in animals vaccinated with strain-19 (S19) and Rose Bengal (RB)-51 strain vaccines can be misinterpreted due to false positives.
Marcelo Ibarra   +5 more
doaj   +2 more sources

Effects of Concurrent Administration of BVDV Modified Live Viral Vaccine and RB51 on Immune Responses in Cattle [PDF]

open access: yesViruses
Cell-mediated immunity is an important component of the immune response for intracellular pathogens. Live vaccines containing different pathogens are used concurrently in the field but are generally licensed individually.
Lauren S. Crawford   +3 more
doaj   +2 more sources

Effectiveness of the RB51 vaccine in controlling brucellosis in adult beef cows [PDF]

open access: yesFrontiers in Veterinary Science
IntroductionThe aim of this study was to compare the effectiveness of brucellosis control and reproductive performance using one or two doses of RB51 strain vaccine.MethodsThis experiment was conducted at two commercial beef farms (A, n = 477; and B, n = 
Carlos Antônio de Carvalho Fernandes   +8 more
doaj   +2 more sources

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