Use of Detergent Extracts of Brucella Abortus RB51 to Detect Serologic Responses in RB51-Vaccinated Cattle [PDF]
Serologic responses to the newly introduced rough Brucella abortus vaccine strain RB51 have been determined in a dot-blot format using γ-irradiated RB51 cells as the antigen. Because γ-irradiated cells are not easily prepared and the signal from cells was not always reliable, an alternative antigen was sought. Detergent extracts of B. abortus RB51 were
S M, Halling, N A, Koster
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Caspase-2-dependent dendritic cell death, maturation, and priming of T cells in response to Brucella abortus infection. [PDF]
Smooth virulent Brucella abortus strain 2308 (S2308) causes zoonotic brucellosis in cattle and humans. Rough B. abortus strain RB51, derived from S2308, is a live attenuated cattle vaccine strain licensed in the USA and many other countries. Our previous
Xinna Li, Yongqun He
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Lymphocyte proliferation in response to Brucella abortus 2308 or RB51 antigens in mice infected with strain 2308, RB51, or 19 [PDF]
Lymphocyte proliferation to 22 protein fractions (106 to 18 kDa) of Brucella abortus 2308 or the lipopolysaccharide O-antigen-deficient mutant of 2308, strain RB51, was measured for 20 weeks after infection of mice with strain 2308, RB51, or 19. Throughout the 20-week study, the 22 protein fractions of 2308 and RB51 induced a similar pattern of ...
M G, Stevens, S C, Olsen, G W, Pugh
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SAFETY OF BRUCELLA ABORTUS STRAIN RB51 IN BLACK BEARS [PDF]
In two studies conducted from October 1999 to March 2000 and December 2000 to April 2001, adult black bears (Ursus americanus) were orally inoculated with 1.4-3.1 x 10(10) colony-forming units (CFU) of Brucella abortus strain RB51 (SRB51, n=12) or 2 ml of 0.15 M NaCl solution (saline, n=11). We did not detect a difference (P>0.05) in antibody titers to
Olsen, Steven C. +4 more
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Bison (Bison bison) heifer calves (n = 32) were randomly assigned to control or vaccination with 1010 colony-forming units of Brucella abortus strain RB51 (RB51) vaccine by single or boostered parenteral delivery, or by surgical implantation of a dry ...
Steven C. Olsen +4 more
doaj +1 more source
Safety of Brucella abortus Strain RB51 in Deer Mice [PDF]
Brucella abortus strain RB51 is an approved brucellosis vaccine for use in cattle that may have potential as an oral vaccine for use in elk (Cervus elaphus) and/or bison (Bison bison). This study was designed to determine effects of strain RB51 on deer mice (Peromyscus maniculatus), a nontarget species that could have access to treated baits in a field
W E, Cook +4 more
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SAFETY OF BRUCELLA ABORTUS STRAIN RB51 IN BULL ELK [PDF]
Some of the elk (Cervus elaphus nelsoni) of the Greater Yellowstone Area (Wyoming, Idaho, Montana; USA) are infected with Brucella abortus, the bacterium that causes bovine brucellosis. Brucella abortus strain RB51 vaccine is being considered as a means to control B. abortus induced abortions in cow elk.
W E, Cook +8 more
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Proteomics and bioinformatics investigations to improve serological diagnosis of canine brucellosis
Abstract Purpose Brucella canis is pathogenic for dogs and humans. Serological diagnosis is a cost‐effective approach for disease surveillance, but a major drawback of current serological tests is the cross‐reactivity with other bacteria that results in false positive reactions.
Mirella Luciani +8 more
wiley +1 more source
Research progress in the therapy of brucellosis
Abstract Brucellosis is a zoonotic bacterial disease posing serious threats to the health of humans and animals. Currently, effective therapeutics available for brucellosis are in urgent demand. Brucellosis is transmitted to humans through diet or contact with infected animals.
Chen Li, Yingdi Wang, Qisheng Peng
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IMMUNE RESPONSES OF ELK TO VACCINATION WITH BRUCELLA ABORTUS STRAIN RB51 [PDF]
In a study conducted from January to August 2000, elk (Cervus elaphus) were vaccinated with Brucella abortus strain RB51 (SRB51, n = 6) or injected with 0.15 M NaCl solution (n = 3) at approximately 6 mo of age. Beginning at 2 wk and continuing to 25 wk after vaccination, SRB51-vaccinated elk had greater antibody responses (P < 0.05) to SRB51 when ...
Steven C, Olsen +2 more
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