Results 41 to 50 of about 178,030 (50)

Clinical significance of metabolism-related genes and FAK activity in ovarian high-grade serous carcinoma

BMC Cancer, 2022
Background Administration of poly (ADP-ribose) polymerase (PARP) inhibitors after achieving a response to platinum-containing drugs significantly prolonged relapse-free survival compared to placebo administration.
Masakazu Sato, Sho Sato, Daisuke Shintani, Mieko Hanaoka, Aiko Ogasawara, Maiko Miwa, Akira Yabuno, Akira Kurosaki, Hiroyuki Yoshida, Keiichi Fujiwara, Kosei Hasegawa   +10 more
doaj   +1 more source

Meta-analysis of health state utility values measured by EuroQol 5-dimensions (EQ5D) questionnaire in Chinese women with breast cancer

BMC Cancer, 2022
Background To synthesise EQ5D health state utility values in Chinese women with breast cancer for parameterising a cost utility model. Methods Eligible studies had to report health state utility values measured by EQ-5D in Chinese women diagnosed with ...
Tamlyn Rautenberg, Brent Hodgkinson, Ute Zerwes, Martin Downes   +3 more
doaj   +1 more source

Anti-PD-1 combined sorafenib versus anti-PD-1 alone in the treatment of advanced hepatocellular cell carcinoma: a propensity score-matching study

BMC Cancer, 2022
Background Vascular endothelial growth factor (VEGF) plays a role in the tumor microenvironment. Sorafenib, which inhibits the VEGF pathway, has an immune-modulation function but lacks substantial clinical data. This study aims to explore the efficacy of
San-Chi Chen, Yi-Hsiang Huang, Ming-Huang Chen, Yi-Ping Hung, Rheun-Chuan Lee, Yu-Yun Shao, Yee Chao   +6 more
doaj   +1 more source

METTL3 promotes colorectal carcinoma progression by regulating the m6A–CRB3–Hippo axis

Journal of Experimental & Clinical Cancer Research, 2022
Background Colorectal carcinoma (CRC) is the third most common cancer and second most common cause of cancer-related deaths worldwide. Ribonucleic acid (RNA) N6-methyladnosine (m6A) and methyltransferase-like 3 (METTL3) play key roles in cancer ...
Jiashu Pan, Feng Liu, Xiaoli Xiao, Ruohui Xu, Liang Dai, Mingzhe Zhu, Hanchen Xu, Yangxian Xu, Aiguang Zhao, Wenjun Zhou, Yanqi Dang, Guang Ji   +11 more
doaj   +1 more source

Circ_0000658 knockdown inhibits epithelial-mesenchymal transition in bladder cancer via miR-498-induced HMGA2 downregulation

Journal of Experimental & Clinical Cancer Research, 2022
Background Epithelial-mesenchymal transition (EMT) has been associated with the angiogenesis and oncogenic phenotypes of multiple malignant tumors including bladder cancer (BCa).
Feng Qiu, Qiuchen Liu, Yanfu Xia, Hengxi Jin, Yuxin Lin, Xiaojun Zhao   +5 more
doaj   +1 more source

Polygenic risk prediction models for colorectal cancer: a systematic review

BMC Cancer, 2022
Background Risk prediction models incorporating single nucleotide polymorphisms (SNPs) could lead to individualized prevention of colorectal cancer (CRC).
Michele Sassano, Marco Mariani, Gianluigi Quaranta, Roberta Pastorino, Stefania Boccia   +4 more
doaj   +1 more source

Prognostic significance of the skeletal muscle index and systemic inflammatory index in patients with lymph node-positive breast cancer after radical mastectomy

BMC Cancer, 2022
Background The role of skeletal muscle index (SMI) and systemic inflammation index (SII) for patients with lymph node-positive breast cancer remain controversial.
Ru Tang, Jia-Peng Deng, Lei Zhang, Wen-Wen Zhang, Jia-Yuan Sun, Feng Chi, Jun Zhang, San-Gang Wu, Zhen-Yu He   +8 more
doaj   +1 more source

Prognostic value and immune relevancy of a combined autophagy-, apoptosis- and necrosis-related gene signature in glioblastoma

BMC Cancer, 2022
Background Glioblastoma (GBM) is considered the most malignant and devastating intracranial tumor without effective treatment. Autophagy, apoptosis, and necrosis, three classically known cell death pathways, can provide novel clinical and immunological ...
Ying Bi, Zeng-Hong Wu, Fei Cao
doaj   +1 more source

Editorial: Advances in the Involvement of Human Papilloma Virus in Head and Neck Squamous Cell Carcinoma

Frontiers in Oncology, 2022
Jerome R. Lechien, Jerome R. Lechien, Jerome R. Lechien, Francois Mouawad, Stéphane Hans, Sven Saussez, Sven Saussez   +6 more
doaj   +1 more source

Editorial: Quantitative Imaging for Clinical Decisions

Frontiers in Oncology, 2022
Nandita Maria deSouza, Daniela Elena Oprea-Lager, Laure S. Fournier   +2 more
doaj   +1 more source