Results 1 to 10 of about 151,505 (53)

TDP-43 Oligomerization and Phase Separation Properties Are Necessary for Autoregulation

Frontiers in Neuroscience, 2022
Loss of TDP-43 protein homeostasis and dysfunction, in particular TDP-43 aggregation, are tied to amyotrophic lateral sclerosis (ALS) and frontotemporal dementia (FTD).
Lydia C. Koehler, Zachary R. Grese, Alliny C. S. Bastos, Lohany D. Mamede, Tomasz Heyduk, Yuna M. Ayala   +5 more
doaj   +1 more source

General and Specific Dimensions of Mood Symptoms Are Associated With Impairments in Common Executive Function in Adolescence and Young Adulthood

Frontiers in Human Neuroscience, 2022
Both unipolar and bipolar depression have been linked with impairments in executive functioning (EF). In particular, mood symptom severity is associated with differences in common EF, a latent measure of general EF abilities.
Elena C. Peterson, Hannah R. Snyder, Chiara Neilson, Benjamin M. Rosenberg, Christina M. Hough, Christina F. Sandman, Leoneh Ohanian, Samantha Garcia, Juliana Kotz, Jamie Finegan, Caitlin A. Ryan, Abena Gyimah, Sophia Sileo, David J. Miklowitz, Naomi P. Friedman, Roselinde H. Kaiser   +15 more
doaj   +1 more source

Tracing Evolving Networks Using Tensor Factorizations vs. ICA-Based Approaches

Frontiers in Neuroscience, 2022
Analysis of time-evolving data is crucial to understand the functioning of dynamic systems such as the brain. For instance, analysis of functional magnetic resonance imaging (fMRI) data collected during a task may reveal spatial regions of interest, and ...
Evrim Acar, Marie Roald, Marie Roald, Khondoker M. Hossain, Vince D. Calhoun, Tülay Adali   +5 more
doaj   +1 more source

Immune Activation in Functional Dyspepsia: Bystander Becoming the Suspect

Frontiers in Neuroscience, 2022
Disorders of gut-brain interaction (DGBI), formerly termed functional gastrointestinal disorders (FGID), are highly prevalent although exact pathophysiological mechanisms remain unclear.
Matthias Ceulemans, Inge Jacobs, Lucas Wauters, Lucas Wauters, Tim Vanuytsel, Tim Vanuytsel   +5 more
doaj   +1 more source

Reward Dependence-Moderated Noradrenergic and Hormonal Responses During Noncompetitive and Competitive Physical Activities

Frontiers in Behavioral Neuroscience, 2022
The aim of this study was to reveal whether increased reward dependence (RD) plays a role in the catecholamine neurotransmitter release and testosterone hormone regulation during physical activities among healthy trained participants.
Zsófia Nagy, Zsófia Nagy, István Karsai, Tamás Nagy, Emese Kátai, Attila Miseta, Gábor Fazekas, András Láng, Ferenc Kocsor, János Kállai   +9 more
doaj   +1 more source

Acupuncture Modulates the Spontaneous Activity and Functional Connectivity of Calcarine in Patients With Chronic Stable Angina Pectoris

Frontiers in Molecular Neuroscience, 2022
BackgroundAcupuncture is an effective adjunctive therapy for chronic stable angina pectoris (CSAP), while the underlying mechanism is unclear. This study aimed to investigate the central pathophysiology of CSAP and explore the mechanism of different ...
Lei Lan, Lei Lan, Tao Yin, Tao Yin, Zilei Tian, Zilei Tian, Ying Lan, Ruirui Sun, Ruirui Sun, Zhengjie Li, Zhengjie Li, Miaomiao Jing, Qiao Wen, Qiao Wen, Shenghong Li, Fanrong Liang, Fanrong Liang, Fang Zeng, Fang Zeng, Fang Zeng   +19 more
doaj   +1 more source

Automatic Reconstruction of Mitochondria and Endoplasmic Reticulum in Electron Microscopy Volumes by Deep Learning

Frontiers in Neuroscience, 2020
Together, mitochondria and the endoplasmic reticulum (ER) occupy more than 20% of a cell's volume, and morphological abnormality may lead to cellular function disorders.
Jing Liu, Jing Liu, Linlin Li, Yang Yang, Bei Hong, Bei Hong, Xi Chen, Qiwei Xie, Qiwei Xie, Hua Han, Hua Han, Hua Han   +11 more
doaj   +1 more source

Reduced complexity of activity patterns in patients with Chronic Fatigue Syndrome: a case control study

BioPsychoSocial Medicine, 2009
Background Chronic fatigue syndrome (CFS) is an illness characterised by pervasive physical and mental fatigue without specific identified pathological changes. Many patients with CFS show reduced physical activity which, though quantifiable, has yielded
Sharpe Michael, Popovic Nikola, Knoop Hans, Burton Christopher, Bleijenberg Gijs   +4 more
doaj   +1 more source

Parental phonological memory contributes to prediction of outcome of late talkers from 20 months to 4 years: a longitudinal study of precursors of specific language impairment

Journal of Neurodevelopmental Disorders, 2012
Background Many children who are late talkers go on to develop normal language, but others go on to have longer-term language difficulties. In this study, we considered which factors were predictive of persistent problems in late talkers.
Bishop Dorothy VM, Holt Georgina, Line Elizabeth, McDonald David, McDonald Sarah, Watt Helen   +5 more
doaj   +1 more source

The CAMH Neuroinformatics Platform: A Hospital-Focused Brain-CODE Implementation

Frontiers in Neuroinformatics, 2018
Investigations of mental illness have been enriched by the advent and maturation of neuroimaging technologies and the rapid pace and increased affordability of molecular sequencing techniques, however, the increased volume, variety and velocity of ...
David J. Rotenberg, Qing Chang, Natalia Potapova, Andy Wang, Marcia Hon, Marcos Sanches, Marcos Sanches, Nikola Bogetic, Nathan Frias, Tommy Liu, Brendan Behan, Rachad El-Badrawi, Stephen C. Strother, Stephen C. Strother, Susan G. Evans, Jordan Mikkelsen, Tom Gee, Tom Gee, Fan Dong, Fan Dong, Stephen R. Arnott, Stephen R. Arnott, Shuai Laing, Shuai Laing, Moyez Dharsee, Anthony L. Vaccarino, Anthony L. Vaccarino, Mojib Javadi, Kenneth R. Evans, Damian Jankowicz   +29 more
doaj   +1 more source