Results 11 to 20 of about 139,134 (53)

Impact of intestinal disorders on central and peripheral nervous system diseases

Neurobiology of Disease, 2022
Brain injuries and neurological diseases have a significant impact on the gut microbiome and the gut barrier. Reciprocally, gut disorders, such as Inflammatory Bowel Syndromes (IBS), can affect the development and pathology of neurodegenerative and ...
Yumna El-Hakim, Shameena Bake, Kathiresh Kumar Mani, Farida Sohrabji   +3 more
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Clinical Correlates Identify ProBDNF and Thrombo-Inflammatory Markers as Key Predictors of Circulating p75NTR Extracellular Domain Levels in Older Adults

Frontiers in Aging Neuroscience, 2022
The p75NTR receptor binds all neurotrophins and is mostly known for its role in neuronal survival and apoptosis. Recently, the extracellular domain (ECD) of p75NTR has been reported in plasma, its levels being dysregulated in numerous neurological ...
Samuel Fleury, Samuel Fleury, Mireille E. Schnitzer, Mireille E. Schnitzer, Lawrence Ledoux-Hutchinson, Imane Boukhatem, Imane Boukhatem, Jean-Christophe Bélanger, Jean-Christophe Bélanger, Mélanie Welman, David Busseuil, Jean-Claude Tardif, Jean-Claude Tardif, Jean-Claude Tardif, Bianca D’Antono, Bianca D’Antono, Marie Lordkipanidzé, Marie Lordkipanidzé   +17 more
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Soluble TREM2: Innocent bystander or active player in neurological diseases?

Neurobiology of Disease, 2022
Triggering receptor expressed on myeloid cells 2 (TREM2) is an innate immune receptor expressed by macrophages and microglia in the central nervous system (CNS). TREM2 has attracted a lot of interest in the past decade for its critical role in modulating
Fabia Filipello, Claire Goldsbury, Shih Feng You, Alberto Locca, Celeste M. Karch, Laura Piccio   +5 more
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Combining Dynamic Network Analysis and Cerebral Carryover Effect to Evaluate the Impacts of Reading Social Media Posts and Science Fiction in the Natural State on the Human Brain

Frontiers in Neuroscience, 2022
Social media has been associated with decreased attention, memory, and learning abilities; however, the underlying mechanisms remain unclear. Dynamic function network connectivity (dFNC) analysis is suitable for uncovering dynamical brain activity ...
Bo Hu, Yu-Ling Cui, Ying Yu, Yu-Ting Li, Lin-Feng Yan, Jing-Ting Sun, Qian Sun, Jing Zhang, Wen Wang, Guang-Bin Cui   +9 more
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Low-intensity blast induces acute glutamatergic hyperexcitability in mouse hippocampus leading to long-term learning deficits and altered expression of proteins involved in synaptic plasticity and serine protease inhibitors

Neurobiology of Disease, 2022
Neurocognitive consequences of blast-induced traumatic brain injury (bTBI) pose significant concerns for military service members and veterans with the majority of “invisible injury.” However, the underlying mechanism of such mild bTBI by low-intensity ...
Shanyan Chen, Heather R. Siedhoff, Hua Zhang, Pei Liu, Ashley Balderrama, Runting Li, Catherine Johnson, C. Michael Greenlief, Bastijn Koopmans, Timothy Hoffman, Ralph G. DePalma, De-Pei Li, Jiankun Cui, Zezong Gu   +13 more
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Intermediate and expanded FMR1 alleles in an autistic Costa Rican population

Revista Mexicana de Neurociencia, 2022
Objective: We aimed to determine the distribution of intermediate and expanded FMR1 alleles in Costa Rican individuals diagnosed with autism. Materials and methods: A total of 212 autism spectrum disorder (ASD) cases of Costa Rican individuals and 943 ...
Rebeca Vindas-Smith, Andrey Sequeira-Cordero, Isabel Castro-Volio, Patricia Jiménez-González, Patricia Cuenca, Manuel Saborío-Rocafort, Marietha Fallas, Melissa Vásquez   +7 more
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A Metabolic Landscape for Maintaining Retina Integrity and Function

Frontiers in Molecular Neuroscience, 2021
Neurons have high metabolic demands that are almost exclusively met by glucose supplied from the bloodstream. Glucose is utilized in complex metabolic interactions between neurons and glia cells, described by the astrocyte-neuron lactate shuttle (ANLS ...
Filipe O. Viegas, Filipe O. Viegas, Stephan C. F. Neuhauss   +2 more
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Hemodynamic Signal Changes During Motor Imagery Task Performance Are Associated With the Degree of Motor Task Learning

Frontiers in Human Neuroscience, 2021
PurposeThis study aimed to investigate whether oxygenated hemoglobin (oxy-Hb) generated during a motor imagery (MI) task is associated with the motor learning level of the task.MethodsWe included 16 right-handed healthy participants who were trained to ...
Naoki Iso, Takefumi Moriuchi, Kengo Fujiwara, Moemi Matsuo, Wataru Mitsunaga, Takashi Hasegawa, Fumiko Iso, Kilchoon Cho, Makoto Suzuki, Toshio Higashi   +9 more
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Blockade of Motor Cortical Long-Term Potentiation Induction by Glutamatergic Dysfunction Causes Abnormal Neurobehavior in an Experimental Subarachnoid Hemorrhage Model

Frontiers in Neural Circuits, 2021
Subarachnoid hemorrhage (SAH) is a life-threatening condition that can also lead to permanent paralysis. However, the mechanisms that underlying neurobehavioral deficits after SAH have not been fully elucidated.
Minoru Fujiki, Kazuhiro Kuga, Harushige Ozaki, Yukari Kawasaki, Hirotaka Fudaba   +4 more
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Binge-Like Ethanol Drinking Increases , , and Gene Expression in the Ventral Tegmental Area of Adult Mice

Neuroscience Insights, 2021
Alcohol use disorder is associated with pathophysiological changes in the dopaminergic system. Orthodenticle homeobox 2 (OTX2) is a transcription factor important for the development of dopaminergic neurons residing in the ventral tegmental area (VTA), a
Cassandre Coles, Amy W Lasek
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