Results 31 to 40 of about 151,505 (53)

Expression and Localization of Kv1.1 and Kv3.1b Potassium Channels in the Cochlear Nucleus and Inferior Colliculus after Long-Term Auditory Deafferentation

open access: yesBrain Sciences, 2020
Deafness affects the expression and distribution of voltage-dependent potassium channels (Kvs) of central auditory neurons in the short-term, i.e., hours to days, but the consequences in the expression of Kvs after long-term deafness remain unknown.
Clara M. Poveda   +6 more
doaj   +1 more source

Selective changes of GABA-A channel subunit mRNAs in the hippocampus and orbitofrontal cortex but not in prefrontal cortex of human alcoholics

open access: yesFrontiers in Cellular Neuroscience, 2012
Alcohol dependence is a common chronic relapsing disorder. The development of alcohol dependence has been associated with changes in brain GABA-A channel-mediated neurotransmission and plasticity.
Zhe eJin   +5 more
doaj   +1 more source

Maresin 1 Attenuates Radicular Pain Through the Inhibition of NLRP3 Inflammasome-Induced Pyroptosis via NF-κB Signaling

open access: yesFrontiers in Neuroscience, 2020
BackgroundThe exposure of the nucleus pulposus (NP) causes an immune and inflammatory response, which is intrinsically linked to the pathogenesis of radicular pain. As a newly discovered pro-resolving lipid mediator, maresin 1 (MaR1) could exert powerful
Yi-hao Wang   +8 more
doaj   +1 more source

Magnitude and Temporal Variability of Inter-stimulus EEG Modulate the Linear Relationship Between Laser-Evoked Potentials and Fast-Pain Perception

open access: yesFrontiers in Neuroscience, 2018
The level of pain perception is correlated with the magnitude of pain-evoked brain responses, such as laser-evoked potentials (LEP), across trials. The positive LEP-pain relationship lays the foundation for pain prediction based on single-trial LEP, but ...
Linling Li   +11 more
doaj   +1 more source

Synaptic Ribbon Active Zones in Cone Photoreceptors Operate Independently from One Another

open access: yesFrontiers in Cellular Neuroscience, 2017
Cone photoreceptors depolarize in darkness to release glutamate-laden synaptic vesicles. Essential to release is the synaptic ribbon, a structure that helps organize active zones by clustering vesicles near proteins that mediate exocytosis, including ...
Justin J. Grassmeyer   +3 more
doaj   +1 more source

Activation of Type 4 Metabotropic Glutamate Receptor Regulates Proliferation and Neuronal Differentiation in a Cultured Rat Retinal Progenitor Cell Through the Suppression of the cAMP/PTEN/AKT Pathway

open access: yesFrontiers in Molecular Neuroscience, 2020
Retinal progenitor cells (RPCs) remain in the eye throughout life and can be characterized by their ability for self-renewal as well as their specialization into different cell types.
Zhichao Zhang   +11 more
doaj   +1 more source

Toward a self-wired active reconstruction of the hippocampal trisynaptic loop: DG-CA3

open access: yesFrontiers in Neural Circuits, 2013
The mammalian hippocampus functions to encode and retrieve memories by transiently changing synaptic strengths, yet encoding in individual subregions for transmission between regions remains poorly understood. Toward the goal of better understanding the
Gregory J. Brewer   +9 more
doaj   +1 more source

Age-related changes in motor cortical representation and interhemispheric interactions: a transcranial magnetic stimulation study.

open access: yesFrontiers in Aging Neuroscience, 2014
To better understand the physiological mechanisms responsible for the differential motor cortex functioning in aging, we used transcranial magnetic stimulation to investigate interhemispheric interactions and cortical representation of hand muscles in ...
Elisabetta eCoppi   +7 more
doaj   +1 more source

A pooling-LiNGAM algorithm for effective connectivity analysis of fMRI data

open access: yesFrontiers in Computational Neuroscience, 2014
The Independent Component Analysis - linear non-Gaussian acyclic model (LiNGAM), an algorithm that can be used to estimate the causal relationship among non-Gaussian distributed data, has the potential value to detect the effective connectivity of human ...
Lele eXu   +10 more
doaj   +1 more source

Inhibition of NF-κB Signaling Pathway by Resveratrol Improves Spinal Cord Injury

open access: yesFrontiers in Neuroscience, 2018
Spinal cord injury (SCI) can have a significant impact on an individual’s life. Herein, we discuss how resveratrol improves SCI by inhibiting nuclear factor kappa-light-chain-enhancer of activated B cells (NF-κB) signaling pathway.
Luyao Xu   +4 more
doaj   +1 more source

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