Results 41 to 50 of about 65,509 (99)

MicroRNA-665 facilitates cell proliferation and represses apoptosis through modulating Wnt5a/β-Catenin and Caspase-3 signaling pathways by targeting TRIM8 in LUSC

open access: yesCancer Cell International, 2021
Background MicroRNAs (miRNAs) are involved in the oncogenesis, development and transformation of lung squamous cell carcinoma (LUSC). miR-665 is clinically significant and acts as a pivotal function in some cancers.
Tian-jun Chen   +6 more
semanticscholar   +1 more source

Ipragliflozin lowers small, dense low-density lipoprotein cholesterol levels in Japanese patients with type 2 diabetes mellitus

open access: yesJournal of Clinical & Translational Endocrinology, 2016
Aims: This preliminary randomized, parallel-group comparative study evaluated the efficacy of ipragliflozin for reduction of small dense low-density lipoprotein cholesterol (sd LDL-C) levels in Japanese patients with type 2 diabetes mellitus (T2DM ...
Yukihiro Bando   +6 more
doaj   +1 more source

Characterisation of Growth Plate Dynamics in Murine Models of Osteoarthritis

open access: yesFrontiers in Endocrinology, 2021
The purpose of this study was to investigate growth plate dynamics in surgical and loading murine models of osteoarthritis, to understand whether abnormalities in these dynamics are associated with osteoarthritis development. 8-week-old C57BL/6 male mice
Hasmik J. Samvelyan   +8 more
doaj   +1 more source

LncRNA LIMT (LINC01089) contributes to sorafenib chemoresistance via regulation of miR-665 and epithelial to mesenchymal transition in hepatocellular carcinoma cells

open access: yesActa Biochimica et Biophysica Sinica, 2021
Hepatocellular carcinoma (HCC) is one of the most malignant tumors worldwide and HCC patients often develop drug resisitene. Long non-coding RNAs (LncRNAs) are closely related to cell cycle, growth, development, differentiation, and apoptosis. Abnormally
Jing Sun   +10 more
semanticscholar   +1 more source

Nesfatin-1 Regulates Feeding, Glucosensing and Lipid Metabolism in Rainbow Trout

open access: yesFrontiers in Endocrinology, 2018
Nesfatin-1 is an 82 amino acid peptide that has been involved in a wide variety of physiological functions in both mammals and fish. This study aimed to elucidate the role of nesfatin-1 on rainbow trout food intake, and its putative effects on glucose ...
Ayelén M. Blanco   +7 more
doaj   +1 more source

Bone metastasis from noninvasive follicular thyroid neoplasm with papillary-like nuclear features (NIFTP); a case report

open access: yesBMC Endocrine Disorders, 2021
Background The term non-invasive follicular thyroid neoplasm with papillary-like nuclear features (NIFTP) was recently proposed as a non-malignant thyroid lesion with indolent behavior that does not require post-operative radio-iodine treatment.
Yasaman Fakhar   +5 more
doaj   +1 more source

Diagnosis of Pituitary Adenoma Biopsies by Ultrahigh Resolution Optical Coherence Tomography Using Neuronal Networks

open access: yesFrontiers in Endocrinology, 2021
ObjectiveDespite advancements of intraoperative visualization, the difficulty to visually distinguish adenoma from adjacent pituitary gland due to textural similarities may lead to incomplete adenoma resection or impairment of pituitary function. The aim
Alexander Micko   +13 more
doaj   +1 more source

Hypertension due to a deoxycorticosteronesecreting adrenal tumour diagnosed during pregnancy

open access: yesEndocrinology, Diabetes & Metabolism Case Reports, 2019
Mineralocorticoid hypertension is most often caused by autonomous overproduction of aldosterone, but excess of other mineralocorticoid precursors can lead to a similar presentation.
Pedro Marques   +4 more
doaj   +1 more source

Self-reported and objectively measured physical activity levels among Hispanic/Latino adults with type 2 diabetes

open access: yesBMJ Open Diabetes Research & Care, 2020
ObjectiveIn the USA, minority populations face a disproportionate burden from type 2 diabetes (T2D), in whom physical activity (PA) is recommended. The aim of this study was to determine levels of PA among a community of free-living Hispanic/Latino ...
Charis Hoppe, Jessikah Morales Glass
doaj   +1 more source

Preference of Women for Gestational Diabetes Screening Method According to Tolerance of Tests and Population Characteristics

open access: yesFrontiers in Endocrinology, 2021
AimsTo determine the preferred method of screening for gestational diabetes mellitus (GDM).Methods1804 women from a prospective study (NCT02036619) received a glucose challenge test (GCT) and 75g oral glucose tolerance test (OGTT) between 24-28 weeks ...
Lore Raets   +20 more
doaj   +1 more source

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