Results 1 to 10 of about 162,445 (96)

Implementasi Standar Audit (SA) 701: Pengomunikasian Hal Audit Utama di Tahun Pertama Penerapan

open access: yesJurnal Akuntansi Manado (JAIM), 2023
Penelitian ini bertujuan untuk menganalisis bagaimana implementasi SA 701 dan apa saja kendala yang dihadapi auditor dalam implementasi SA 701 di tahun pertama penerapannya.
Marina Lauren, Aria Farah Mita
semanticscholar   +1 more source

Efficacy and safety of a new ranibizumab biosimilar CKD-701 using a pro re nata treatment regimen in neovascular age-related macular degeneration: A phase 3 randomized clinical trial

open access: yesPLoS ONE, 2022
Purpose This study aimed to establish the efficacy, safety, and immunogenicity equivalence of the proposed biosimilar CKD-701 with the reference ranibizumab in patients with treatment-naïve neovascular age-related macular degeneration (nAMD).
C. Yoon   +5 more
semanticscholar   +1 more source

INZ‐701, a recombinant ENPP1 enzyme, prevents ectopic calcification in an Abcc6−/− mouse model of pseudoxanthoma elasticum

open access: yesExperimental Dermatology, 2022
Pseudoxanthoma elasticum (PXE), a heritable multisystem ectopic calcification disorder, is predominantly caused by inactivating mutations in ABCC6. The encoded protein, ABCC6, is a hepatic efflux transporter and a key regulator of extracellular inorganic
I. Jacobs   +9 more
semanticscholar   +1 more source

INZ‐701 Prevents Ectopic Tissue Calcification and Restores Bone Architecture and Growth in ENPP1‐Deficient Mice

open access: yesJournal of Bone and Mineral Research, 2021
Ectonucleotide pyrophosphatase/phosphodiesterase 1 (ENPP1) is the major enzyme that cleaves extracellular adenosine triphosphate (ATP) to generate pyrophosphate (PPi), an inorganic metabolite with potent anticalcification activity.
Zhiliang Cheng   +8 more
semanticscholar   +1 more source

Patency of conduits in patients who received internal mammary artery, radial artery and saphenous vein grafts

open access: yesBMC Cardiovascular Disorders, 2020
Background Where each patient has all three conduits of internal mammary artery (IMA), saphenous vein graft (SVG) and radial artery (RA), most confounders affecting comparison between conduits can be mitigated. Additionally, since SVG progressively fails
Alistair Royse   +8 more
doaj   +1 more source

EVT‐701 is a novel selective and safe mitochondrial complex 1 inhibitor with potent anti‐tumor activity in models of solid cancers

open access: yesPharmacology Research & Perspectives, 2021
Targeting the first protein complex of the mitochondrial electron transport chain (MC1) in cancer has become an attractive therapeutic approach in the recent years, given the metabolic vulnerabilities of cancer cells. The anticancer effect exerted by the
Raquel Luna Yolba   +7 more
semanticscholar   +1 more source

Taquicardia ventricular associada com linfoma não-Hodgkin

open access: yesArquivos Brasileiros de Cardiologia, 2011
Linfoma não-Hodgkin sistêmico pode afetar o miocárdio, particularmente em pacientes imunocomprometidos. Quando presentes, sinais e sintomas são geralmente inespecíficos, tornando o diagnóstico de envolvimento cardíaco muito difícil antes da autópsia ...
Diego Chemello   +3 more
doaj   +1 more source

The immunomodulatory drugs lenalidomide and pomalidomide enhance the potency of AMG 701 in multiple myeloma preclinical models.

open access: yesBlood Advances, 2020
We investigated here the novel immunomodulation and anti-multiple myeloma (MM) function of T cells engaged by the bispecific T-cell engager molecule AMG 701, and further examined the impact of AMG 701 in combination with immunomodulatory drugs (IMiDs ...
Shih-Feng Cho   +13 more
semanticscholar   +1 more source

Influence of Spironolactone on Matrix Metalloproteinase-2 in Acute Decompensated Heart Failure

open access: yesArquivos Brasileiros de Cardiologia, 2015
Background: Matrix metalloproteinases (MMPs) are a family of enzymes important for the resorption of extracellular matrices, control of vascular remodeling and repair.
João Pedro Ferreira   +5 more
doaj   +1 more source

Association of circulating PCSK9 concentration with cardiovascular metabolic markers and outcomes in stable coronary artery disease patients with or without diabetes: a prospective, observational cohort study

open access: yesCardiovascular Diabetology, 2020
Background Whether plasma proprotein convertase subtilisin/kexin type 9 (PCSK9) levels is a predictor for cardiovascular outcomes has currently been controversial. No data is currently available regarding the relation of PCSK9 to cardiovascular metabolic
Jia Peng   +10 more
doaj   +1 more source

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