Rc666-701 - Open Access .click

Results 71 to 80 of about 177,998 (114)

Ischemic Evaluation in New‐Onset Methamphetamine‐Associated Heart Failure

Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease
Cooper B. Kersey +4 more
doaj +1 more source

Non–ST‐Segment–Elevation Myocardial Infarction and ST‐Segment–Elevation Myocardial Infarction Outcomes After a Percutaneous Coronary Intervention–Capable Facility Opening by Patient Race and Community Segregation

Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease
Yu‐Chu Shen, Madeline Feldmeier, Renee Y. Hsia +2 more
doaj +1 more source

The 35 th Great Wall International Congress of Cardiology Asian Heart Society Congress 2024

Cardiovascular Innovations and Applications
doaj +1 more source

Interatrial Block in the Presence of Lipomatous Atrial Septal Hypertrophy

Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease
Abdulaziz Malik +7 more
doaj +1 more source

AMG 701 induces cytotoxicity of multiple myeloma cells and depletes plasma cells in cynomolgus monkeys

Blood Advances, 2020
Multiple myeloma (MM) is a hematologic malignancy that is characterized by the accumulation of abnormal plasma cells (PCs) in the bone marrow (BM). Patient outcome may be improved with BiTE (bispecific T-cell engager) molecules, which redirect T cells to
Ana Goyos, Chi-Ming Li
exaly +2 more sources

Identification, Cloning and Heterologous Expression of the Gene Cluster Directing RES-701-3, -4 Lasso Peptides Biosynthesis from a Marine Streptomyces Strain

Marine Drugs, 2020
RES-701-3 and RES-701-4 are two class II lasso peptides originally identified in the fermentation broth of Streptomyces sp. RE-896, which have been described as selective endothelin type B receptor antagonists. These two lasso peptides only differ in the
Daniel Oves-Costales +2 more
exaly +2 more sources

The immunomodulatory drugs lenalidomide and pomalidomide enhance the potency of AMG 701 in multiple myeloma preclinical models

Blood Advances, 2020
We investigated here the novel immunomodulation and anti-multiple myeloma (MM) function of T cells engaged by the bispecific T-cell engager molecule AMG 701, and further examined the impact of AMG 701 in combination with immunomodulatory drugs (IMiDs ...
Shih-Feng Cho, Liang Lin, Lijie Xing
exaly +2 more sources

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Tern-701 (HS-10382) Is a Potent Inhibitor of BCR::ABL1 and Is Synergistic with Active Site Tyrosine Kinase Inhibitors

Blood, 2023
Although tyrosine kinase inhibitors (TKIs) targeting the ATP-binding site of the BCR::ABL1 oncoprotein are effective therapeutics for chronic myeloid leukemia (CML), patients often develop drug resistance due to ATP-site mutations that inhibit drug ...
Benjamin M Parsons, J. Jasper, Christopher Jones +2 more
semanticscholar +1 more source

Abstract 3328: Antitumor activity of BLU-945 and BLU-701 as single agents and in combination in EGFR L858R-driven models of NSCLC

Cancer Research, 2022
BACKGROUND: Lung cancer is the leading cause of cancer death globally. EGFR mutations are the most common genomic drivers of non-small cell lung cancer (NSCLC), occurring in ~17% and up to 50% of Caucasian and Asian patients, respectively, with exon 19
L. Tavera +16 more
semanticscholar +1 more source

A phase 1/2 study of the highly selective EGFR inhibitor, BLU-701, in patients with EGFR-mutant non–small cell lung cancer (NSCLC).

Journal of Clinical Oncology, 2022
TPS9142 Background: Although 3rd-generation tyrosine kinase inhibitors (TKIs), such as osimertinib, are highly effective in front-line metastatic EGFR-mutated ( EGFRm) NSCLC, treatment resistance ultimately occurs, including the emergence of the on ...
A. Spira +18 more
semanticscholar +1 more source

heart failure
prognosis